4V4H
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![BU of 4v4h by Molmil](/molmil-images/mine/4v4h) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution. | Descriptor: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ... | Authors: | Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D. | Deposit date: | 2006-08-04 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structural analysis of kasugamycin inhibition of translation. Nat.Struct.Mol.Biol., 13, 2006
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4V8S
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![BU of 4v8s by Molmil](/molmil-images/mine/4v8s) | Archaeal RNAP-DNA binary complex at 4.32Ang | Descriptor: | 5'-D(*AP*TP*AP*GP*AP*GP*TP*AP*TP*AP*AP*GP*AP*TP *AP*G)-3', 5'-D(*TP*CP*TP*TP*AP*TP*AP*CP*TP*CP*TP*AP*TP*CP)-3', DNA-DIRECTED RNA POLYMERASE, ... | Authors: | Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2012-07-12 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.323 Å) | Cite: | Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA. Nucleic Acids Res., 40, 2012
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4W93
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![BU of 4w93 by Molmil](/molmil-images/mine/4w93) | Human pancreatic alpha-amylase in complex with montbretin A | Descriptor: | CALCIUM ION, CHLORIDE ION, Montbretin A, ... | Authors: | Williams, L.K, Caner, S, Brayer, G.D. | Deposit date: | 2014-08-27 | Release date: | 2015-07-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.352 Å) | Cite: | The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif. Nat.Chem.Biol., 11, 2015
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7C2O
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![BU of 7c2o by Molmil](/molmil-images/mine/7c2o) | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, R-specific carbonyl reductase, ... | Authors: | Vinaykumar, K, KanalElamparithi, B, Chaudhury, D, Gunasekaran, K, Chadha, A. | Deposit date: | 2020-05-08 | Release date: | 2020-05-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT To Be Published
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6KQ8
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![BU of 6kq8 by Molmil](/molmil-images/mine/6kq8) | 328 K cryoEM structure of Sso-KARI in complex with Mg2+ | Descriptor: | Ketol-acid reductoisomerase, MAGNESIUM ION | Authors: | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | Deposit date: | 2019-08-16 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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7RC3
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![BU of 7rc3 by Molmil](/molmil-images/mine/7rc3) | Aeronamide N-methyltransferase, AerE (Y137F) | Descriptor: | ASPARTIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ... | Authors: | Cogan, D.P, Reyes, R, Nair, S.K. | Deposit date: | 2021-07-07 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins. Proc.Natl.Acad.Sci.USA, 119, 2022
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1VRZ
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![BU of 1vrz by Molmil](/molmil-images/mine/1vrz) | Helix turn helix motif | Descriptor: | ACETATE ION, DE NOVO DESIGNED 21 RESIDUE PEPTIDE | Authors: | Rudresh, Ramakumar, S, Ramagopal, U.A, Inai, Y, Sahal, D. | Deposit date: | 2005-10-14 | Release date: | 2005-11-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | De Novo Design and Characterization of a Helical Hairpin Eicosapeptide; Emergence of an Anion Receptor in the Linker Region. Structure, 12, 2004
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7RC4
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![BU of 7rc4 by Molmil](/molmil-images/mine/7rc4) | Aeronamide N-methyltransferase, AerE (D141A) | Descriptor: | CALCIUM ION, HEXAETHYLENE GLYCOL, Methyltransferase family protein, ... | Authors: | Cogan, D.P, Reyes, R, Nair, S.K. | Deposit date: | 2021-07-07 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins. Proc.Natl.Acad.Sci.USA, 119, 2022
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6DLU
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![BU of 6dlu by Molmil](/molmil-images/mine/6dlu) | Cryo-EM of the GMPPCP-bound human dynamin-1 polymer assembled on the membrane in the constricted state | Descriptor: | Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. | Deposit date: | 2018-06-02 | Release date: | 2018-08-01 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
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1HSQ
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![BU of 1hsq by Molmil](/molmil-images/mine/1hsq) | SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA | Descriptor: | PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN) | Authors: | Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F. | Deposit date: | 1994-06-13 | Release date: | 1994-08-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the SH3 domain of phospholipase C-gamma. Cell(Cambridge,Mass.), 72, 1993
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7RC5
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![BU of 7rc5 by Molmil](/molmil-images/mine/7rc5) | Aeronamide N-methyltransferase, AerE (N231A) | Descriptor: | CALCIUM ION, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Cogan, D.P, Reyes, R, Nair, S.K. | Deposit date: | 2021-07-07 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins. Proc.Natl.Acad.Sci.USA, 119, 2022
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6KP2
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![BU of 6kp2 by Molmil](/molmil-images/mine/6kp2) | |
1I04
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![BU of 1i04 by Molmil](/molmil-images/mine/1i04) | CRYSTAL STRUCTURE OF MOUSE MAJOR URINARY PROTEIN-I FROM MOUSE LIVER | Descriptor: | MAJOR URINARY PROTEIN I | Authors: | Timm, D.E, Baker, L.J, Mueller, H, Zidek, L, Novotny, M.V. | Deposit date: | 2001-01-28 | Release date: | 2001-02-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of pheromone binding to mouse major urinary protein (MUP-I) Protein Sci., 10, 2001
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7RQY
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![BU of 7rqy by Molmil](/molmil-images/mine/7rqy) | Cryo-EM structure of the full-length TRPV1 with RTx at 25 degrees Celsius, in an open state, class B | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily V member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, ... | Authors: | Kwon, D.H, Suo, Y, Lee, S.-Y. | Deposit date: | 2021-08-08 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13, 2022
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7RQU
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![BU of 7rqu by Molmil](/molmil-images/mine/7rqu) | Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in a closed state, class I | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, SODIUM ION, ... | Authors: | Kwon, D.H, Suo, Y, Lee, S.-Y. | Deposit date: | 2021-08-08 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13, 2022
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6KOT
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![BU of 6kot by Molmil](/molmil-images/mine/6kot) | |
7RQV
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![BU of 7rqv by Molmil](/molmil-images/mine/7rqv) | Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an intermediate-closed state, class II | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | Authors: | Kwon, D.H, Suo, Y, Lee, S.-Y. | Deposit date: | 2021-08-08 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13, 2022
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1I1H
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![BU of 1i1h by Molmil](/molmil-images/mine/1i1h) | CRYSTAL STRUCTURE ANALYSIS OF PRECORRIN-8X METHYLMUTASE COMPLEX WITH HYDROGENOBYRINIC ACID | Descriptor: | HYDROGENOBYRINIC ACID, PRECORRIN-8X METHYLMUTASE | Authors: | Shipman, L.W, Li, D, Roessner, C.A, Scott, A.I, Sacchettini, J.C. | Deposit date: | 2001-02-01 | Release date: | 2001-07-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of precorrin-8x methyl mutase. Structure, 9, 2001
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1W3D
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![BU of 1w3d by Molmil](/molmil-images/mine/1w3d) | |
6KVP
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![BU of 6kvp by Molmil](/molmil-images/mine/6kvp) | S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2) | Descriptor: | 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ... | Authors: | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | Deposit date: | 2019-09-05 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9, 2019
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7RM8
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![BU of 7rm8 by Molmil](/molmil-images/mine/7rm8) | |
7R9B
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![BU of 7r9b by Molmil](/molmil-images/mine/7r9b) | |
1VOP
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![BU of 1vop by Molmil](/molmil-images/mine/1vop) | |
4U1K
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![BU of 4u1k by Molmil](/molmil-images/mine/4u1k) | HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | Deposit date: | 2014-07-15 | Release date: | 2015-04-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology, 12, 2015
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6DHA
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![BU of 6dha by Molmil](/molmil-images/mine/6dha) | |