6KPK
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![BU of 6kpk by Molmil](/molmil-images/mine/6kpk) | 309 K cryoEM structure of Sso-KARI in complex with Mg2+ | Descriptor: | Ketol-acid reductoisomerase, MAGNESIUM ION | Authors: | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | Deposit date: | 2019-08-15 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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4U6U
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1W08
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![BU of 1w08 by Molmil](/molmil-images/mine/1w08) | STRUCTURE OF T70N HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME | Authors: | Johnson, R, Christodoulou, J, Luisi, B, Dumoulin, M, Caddy, G, Alcocer, M, Murtagh, G, Archer, D.B, Dobson, C.M. | Deposit date: | 2004-06-02 | Release date: | 2004-06-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rationalising Lysozyme Amyloidosis: Insights from the Structure and Solution Dynamics of T70N Lysozyme. J.Mol.Biol., 352, 2005
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7RDN
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![BU of 7rdn by Molmil](/molmil-images/mine/7rdn) | Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (Pml39) | Descriptor: | Pre-mRNA leakage protein 39, ZINC ION | Authors: | Hashimoto, H, Ramirez, D.H, Pawlak, N, Blobel, G, Palancade, B, Debler, E.W. | Deposit date: | 2021-07-09 | Release date: | 2022-07-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules. Sci Rep, 12, 2022
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6L89
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![BU of 6l89 by Molmil](/molmil-images/mine/6l89) | Human PPARgamma ligand binding domain complexed with Butyrolactone 1 | Descriptor: | Peroxisome proliferator-activated receptor gamma, methyl (2R)-3-(4-hydroxyphenyl)-2-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate | Authors: | Jang, D.M, Han, B.W. | Deposit date: | 2019-11-05 | Release date: | 2020-09-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor gamma. Biomolecules, 10, 2020
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8H8B
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![BU of 8h8b by Molmil](/molmil-images/mine/8h8b) | Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form | Descriptor: | Putative Rhs-family protein | Authors: | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | Deposit date: | 2022-10-22 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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8H8A
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![BU of 8h8a by Molmil](/molmil-images/mine/8h8a) | Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form | Descriptor: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | Authors: | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | Deposit date: | 2022-10-22 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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6LEV
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![BU of 6lev by Molmil](/molmil-images/mine/6lev) | Quadruple mutant (N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 46 and NADPH | Descriptor: | 2-[[4,6-bis(azanyl)-2,2-dimethyl-1,3,5-triazin-1-yl]oxy]-N-(4-chlorophenyl)ethanamide, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Vanichtanankul, J, Vitsupakorn, D. | Deposit date: | 2019-11-27 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.644 Å) | Cite: | Flexible diaminodihydrotriazine inhibitors of Plasmodium falciparum dihydrofolate reductase: Binding strengths, modes of binding and their antimalarial activities. Eur.J.Med.Chem., 195, 2020
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7QYZ
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![BU of 7qyz by Molmil](/molmil-images/mine/7qyz) | Crystal structure of a DyP-type peroxidase 6E10 variant from Pseudomonas putida | Descriptor: | Dyp-type peroxidase family protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Borges, P.T, Silva, D, Martins, L.O, Frazao, C. | Deposit date: | 2022-01-30 | Release date: | 2022-08-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.452 Å) | Cite: | Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase. Comput Struct Biotechnol J, 20, 2022
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6DIY
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![BU of 6diy by Molmil](/molmil-images/mine/6diy) | YTFGQ segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 96-100, assembled as an amyloid fibril | Descriptor: | YTFGQ segment Light-Chain Variable Domain Kappa AL09 | Authors: | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-05-24 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis. J. Biol. Chem., 293, 2018
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6KPR
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4TX6
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![BU of 4tx6 by Molmil](/molmil-images/mine/4tx6) | AfChiA1 in complex with compound 1 | Descriptor: | 3-(2-methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-d]pyrimidin-4(5H)-one, Class III chitinase ChiA1, PHOSPHATE ION | Authors: | van Aalten, D.M.F. | Deposit date: | 2014-07-02 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors FEBS Lett, 588, 2014
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7RRW
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![BU of 7rrw by Molmil](/molmil-images/mine/7rrw) | Monomeric CRM197 expressed in E. coli | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Diphtheria toxin | Authors: | Gallagher, D.T, Lees, A. | Deposit date: | 2021-08-10 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Monomeric crystal structure of the vaccine carrier protein CRM 197 and implications for vaccine development. Acta Crystallogr.,Sect.F, 79, 2023
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7RPN
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6KUW
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![BU of 6kuw by Molmil](/molmil-images/mine/6kuw) | Crystal structure of human alpha2C adrenergic G protein-coupled receptor. | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (8~{a}~{R},12~{a}~{S},13~{a}~{R})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine, Alpha-2C adrenergic receptor, ... | Authors: | Chen, X.Y, Wu, L.J, Wu, D, Zhong, G.S. | Deposit date: | 2019-09-02 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human alpha2C adrenergic G protein-coupled receptor. To Be Published
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1IB9
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7R2E
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![BU of 7r2e by Molmil](/molmil-images/mine/7r2e) | Structure of human Senp7 with SUMO2 | Descriptor: | Sentrin-specific protease 7, Small ubiquitin-related modifier 3, prop-2-en-1-amine | Authors: | Reverter, D, Li, Y. | Deposit date: | 2022-02-04 | Release date: | 2022-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural Basis for the SUMO2 Isoform Specificity of SENP7. J.Mol.Biol., 434, 2022
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4UEB
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4UAM
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![BU of 4uam by Molmil](/molmil-images/mine/4uam) | 1.8 Angstrom crystal structure of IMP-1 metallo-beta-lactamase with a mixed iron-zinc center in the active site | Descriptor: | CITRATE ANION, FE (III) ION, IMP-1 metallo-beta-lactamase, ... | Authors: | Carruthers, T.J, Carr, P.D, Jackson, C.J, Otting, G. | Deposit date: | 2014-08-11 | Release date: | 2014-09-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Iron(III) Located in the Dinuclear Metallo-beta-Lactamase IMP-1 by Pseudocontact Shifts. Angew.Chem.Int.Ed.Engl., 53, 2014
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7QYY
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![BU of 7qyy by Molmil](/molmil-images/mine/7qyy) | Vanadium-dependent bromoperoxidase from Corallina pilulifera in complex with chloride | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Isupov, M.N, Mitchell, D, Littelchild, J.A, Garcia-Rodriguez, E. | Deposit date: | 2022-01-29 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | R396W mutant of the vanadium-dependent bromoperoxidase from Corallina pilulifera To Be Published
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1W0B
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![BU of 1w0b by Molmil](/molmil-images/mine/1w0b) | Solution structure of the human alpha-hemoglobin stabilizing protein (AHSP) P30A mutant | Descriptor: | ALPHA-HEMOGLOBIN STABILIZING PROTEIN | Authors: | Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M. | Deposit date: | 2004-06-01 | Release date: | 2004-06-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding. J. Biol. Chem., 279, 2004
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1W0A
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![BU of 1w0a by Molmil](/molmil-images/mine/1w0a) | Solution structure of the trans form of the human alpha-hemoglobin stabilizing protein (AHSP) | Descriptor: | ALPHA-HEMOGLOBIN STABILIZING PROTEIN | Authors: | Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M. | Deposit date: | 2004-06-01 | Release date: | 2004-06-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding. J. Biol. Chem., 279, 2004
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1WA8
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![BU of 1wa8 by Molmil](/molmil-images/mine/1wa8) | Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria | Descriptor: | 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6), ESAT-6 LIKE PROTEIN ESXB | Authors: | Renshaw, P.S, Lightbody, K.L, Veverka, V, Muskett, F.W, Kelly, G, Frenkiel, T.A, Gordon, S.V, Hewinson, R.G, Burke, B, Norman, J, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-10-25 | Release date: | 2005-06-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6 Embo J., 24, 2005
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6L6O
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![BU of 6l6o by Molmil](/molmil-images/mine/6l6o) | Crystal structure of stabilized Rab5a GTPase domain from Leishmania donovani | Descriptor: | ACETATE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Arora, A, Zohib, M, Biswal, B.K, Maheshwari, D, Pal, R.K. | Deposit date: | 2019-10-29 | Release date: | 2020-11-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the GDP-bound GTPase domain of Rab5a from Leishmania donovani. Acta Crystallogr.,Sect.F, 76, 2020
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1VZS
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![BU of 1vzs by Molmil](/molmil-images/mine/1vzs) | Solution structure of subunit F6 from the peripheral stalk region of ATP synthase from bovine heart mitochondria | Descriptor: | ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL PRECURSOR | Authors: | Carbajo, R.J, Silvester, J.A, Runswick, M.J, Walker, J.E, Neuhaus, D. | Deposit date: | 2004-05-25 | Release date: | 2004-09-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of Subunit F(6) from the Peripheral Stalk Region of ATP Synthase from Bovine Heart Mitochondria J.Mol.Biol., 342, 2004
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