8PRL
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8PRJ
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8PRR
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8PRF
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8PRP
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2UV3
| Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | 著者 | Hatherley, D, Harlos, K, Dunlop, D.C, Stuart, D.I, Barclay, A.N. | 登録日 | 2007-03-08 | 公開日 | 2007-03-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors. J.Biol.Chem., 282, 2007
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8PRT
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5CYI
| CDK2/Cyclin A covalent complex with 6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine (NU6300) | 分子名称: | 6-(cyclohexylmethoxy)-N-[4-(ethylsulfonyl)phenyl]-9H-purin-2-amine, Cyclin-A2, Cyclin-dependent kinase 2 | 著者 | Anscombe, E, Meschini, E, Vidal, R.M, Martin, M.P, Staunton, D, Geitmann, M, Danielson, U.H, Stanley, W.A, Wang, L.Z, Reuillon, T, Golding, B.T, Cano, C, Newell, D.R, Noble, M.E.M, Wedge, S.R, Endicott, J.A, Griffin, R.J. | 登録日 | 2015-07-30 | 公開日 | 2015-09-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem.Biol., 22, 2015
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2VFL
| AKAP18 delta central domain - CMP | 分子名称: | AKAP18 DELTA, CYTIDINE-5'-MONOPHOSPHATE | 著者 | Gold, M.G, Smith, F.D, Scott, J.D, Barford, D. | 登録日 | 2007-11-05 | 公開日 | 2008-05-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Akap18 Contains a Phosphoesterase Domain that Binds AMP J.Mol.Biol., 375, 2008
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2VFK
| AKAP18 delta central domain - AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, AKAP18 DELTA | 著者 | Gold, M.G, Smith, F.D, Scott, J.D, Barford, D. | 登録日 | 2007-11-05 | 公開日 | 2008-05-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Akap18 Contains a Phosphoesterase Domain that Binds AMP J.Mol.Biol., 375, 2008
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7ZOA
| cryo-EM structure of CGT ABC transporter in presence of CBG substrate | 分子名称: | Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, Cyclooctadecakis-(1-2)-(beta-D-glucopyranose) | 著者 | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | 登録日 | 2022-04-24 | 公開日 | 2022-12-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella. Nat.Struct.Mol.Biol., 29, 2022
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1JZA
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6W05
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1SX6
| Crystal structure of human Glycolipid Transfer protein in lactosylceramide-bound form | 分子名称: | Glycolipid transfer protein, N-OCTANE, OLEIC ACID, ... | 著者 | Malinina, L, Malakhova, M.L, Teplov, A, Brown, R.E, Patel, D.J. | 登録日 | 2004-03-30 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis for glycosphingolipid transfer specificity. Nature, 430, 2004
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6PL5
| Structural coordination of polymerization and crosslinking by a peptidoglycan synthase complex | 分子名称: | Penicillin-binding protein 2/cell division protein FtsI, Peptidoglycan glycosyltransferase RodA, Unknown peptide | 著者 | Sjodt, M, Rohs, P.D.A, Erlandson, S.C, Zheng, S, Rudner, D.Z, Bernhardt, T.G, Kruse, A.C. | 登録日 | 2019-06-30 | 公開日 | 2020-03-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nat Microbiol, 5, 2020
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6PM9
| Crystal structure of the core catalytic domain of human O-GlcNAcase bound to MK-8719 | 分子名称: | (3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(ethylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain | 著者 | Klein, D.J, Selnick, H.G, Duffy, J.L, McEachern, E.J. | 登録日 | 2019-07-01 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J.Med.Chem., 62, 2019
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3ZEU
| Structure of a Salmonella typhimurium YgjD-YeaZ heterodimer bound to ATPgammaS | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Nichols, C.E, Lamb, H.K, Thompson, P, El Omari, K, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K. | 登録日 | 2012-12-07 | 公開日 | 2013-03-20 | 最終更新日 | 2017-03-29 | 実験手法 | X-RAY DIFFRACTION (1.653 Å) | 主引用文献 | Crystal Structure of the Dimer of Two Essential Salmonella Typhimurium Proteins, Ygjd & Yeaz and Calorimetric Evidence for the Formation of a Ternary Ygjd-Yeaz-Yjee Complex. Protein Sci., 22, 2013
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4RFO
| Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade A/E gp120, N60-i3 Fab heavy chain, ... | 著者 | Tolbert, W.D, Gohain, N, Pazgier, M. | 登録日 | 2014-09-26 | 公開日 | 2015-07-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
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5CU3
| Crystal structure of CK2alpha bound to CAM4066 | 分子名称: | ACETATE ION, Casein kinase II subunit alpha, DIMETHYL SULFOXIDE, ... | 著者 | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | 登録日 | 2015-07-24 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | 主引用文献 | Specific inhibition of CK2 alpha from an anchor outside the active site. Chem Sci, 7, 2016
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7SOZ
| Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates chemically crosslinked (5 mg/mL EDC, 12 hours). | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Ward, A.R, Snow, C.D. | 登録日 | 2021-11-01 | 公開日 | 2021-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds. Acs Nano, 17, 2023
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7SPM
| Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates chemically crosslinked (30 mg/mL EDC, 12 hours, 2 doses). | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Ward, A.R, Snow, C.D. | 登録日 | 2021-11-02 | 公開日 | 2021-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Stabilizing DNA-Protein Co-Crystals via Intra-Crystal Chemical Ligation of the DNA Crystals, 12, 2022
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5CZO
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1JFA
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5K4X
| M. thermoresistible IMPDH in complex with IMP and Compound 1 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide | 著者 | Pacitto, A, Ascher, D.B, Blundell, T.L. | 登録日 | 2016-05-22 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
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6CR0
| 1.55 A resolution structure of (S)-6-hydroxynicotine oxidase from Shinella HZN7 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-6-hydroxynicotine oxidase, ACETATE ION, ... | 著者 | Deay III, D, Lovell, S, Battaile, K.P, Petillo, P, Richter, M. | 登録日 | 2018-03-16 | 公開日 | 2018-03-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.548 Å) | 主引用文献 | Improving the kinetic parameters of nicotine oxidizing enzymes by homologous structure comparison and rational design Arch.Biochem.Biophys., 2022
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