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PDB: 53526 件

2FQ1
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Crystal structure of the two-domain non-ribosomal peptide synthetase EntB containing isochorismate lyase and aryl-carrier protein domains
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isochorismatase, ...
著者Drake, E.J, Nicolai, D.A, Gulick, A.M.
登録日2006-01-17
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.
Chem.Biol., 13, 2006
6U9P
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Wild-type MthK pore in ~150 mM K+
分子名称: Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION
著者Posson, D.J, Nimigean, C.M.
登録日2019-09-09
公開日2020-11-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
8DTM
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BU of 8dtm by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 component 2
分子名称: Insulin mimetic peptide S597 component 2, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-26
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
6UKP
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Apo mBcs1
分子名称: Mitochondrial chaperone BCS1
著者Tang, W.K, Borgnia, M.J, Hsu, A.L, Xia, D.
登録日2019-10-05
公開日2020-02-12
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
3CXP
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BU of 3cxp by Molmil
Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 mutant E156A
分子名称: CHLORIDE ION, Glucosamine 6-phosphate N-acetyltransferase
著者Wang, J, Liu, X, Li, L.-F, Su, X.-D.
登録日2008-04-25
公開日2008-09-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
6ULK
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Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LD8
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Crystal structure of cystathionine gamma synthase from Xanthomonas oryzae pv. oryzae in complex with aminoacrylate and cysteine
分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, CYSTEINE, Cystathionine gamma-synthase
著者Ngo, H.P.T, Nguyen, T.D.Q, Kang, L.W.
登録日2019-11-20
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of cystathionine gamma synthase from Xanthomonas oryzae pv. oryzae in complex with aminoacrylate and cysteine
To Be Published
4V0C
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BU of 4v0c by Molmil
Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin
分子名称: CALCIUM ION, CALMODULIN, POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, ...
著者Sachyani, D, Hirsch, J.A.
登録日2014-09-14
公開日2014-11-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin.
Structure, 22, 2014
3CVA
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BU of 3cva by Molmil
Human Bcl-xL containing a Trp to Ala mutation at position 137
分子名称: Apoptosis regulator Bcl-X
著者Feng, Y, Zhang, L, Hu, T, Shen, X, Chen, K, Jiang, H, Liu, D.
登録日2008-04-18
公開日2009-03-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
Arch.Biochem.Biophys., 484, 2009
2QGY
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BU of 2qgy by Molmil
Crystal structure of an enolase from the environmental genome shotgun sequencing of the Sargasso Sea
分子名称: Enolase from the environmental genome shotgun sequencing of the Sargasso Sea, MAGNESIUM ION
著者Bonanno, J.B, Gilmore, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-06-29
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of an enolase from the environmental genome shotgun sequencing of the Sargasso Sea.
To be Published
6UCC
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BU of 6ucc by Molmil
Structure of human PACRG-MEIG1 complex (limited proteolysis)
分子名称: DI(HYDROXYETHYL)ETHER, Meiosis expressed gene 1 protein homolog, PHOSPHATE ION, ...
著者Khan, N, Croteau, N, Pelletier, D, Veyron, S, Trempe, J.F.
登録日2019-09-16
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human PACRG in complex with MEIG1
Biorxiv, 2019
2FRF
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Horse Heart Myoglobin, Nitrite Adduct, Crystal Soak
分子名称: Myoglobin, NITRITE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Copeland, D.M, Soares, A.S, West, A.H, Richter-Addo, G.B.
登録日2006-01-19
公開日2006-05-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
J.Inorg.Biochem., 100, 2006
6UFO
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BU of 6ufo by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]-1-methoxyheptan-2-one
分子名称: 7-[(3-aminopropyl)amino]-1-methoxyheptane-2,2-diol, PHOSPHATE ION, POTASSIUM ION, ...
著者Herbst-Gervasoni, C.J, Christianson, D.W.
登録日2019-09-24
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation.
Biochemistry, 58, 2019
2FN0
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BU of 2fn0 by Molmil
Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)
分子名称: ACETATE ION, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kerbarh, O, Chirgadze, D.Y, Blundell, T.L, Abell, C.
登録日2006-01-10
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structures of Yersinia enterocolitica Salicylate Synthase and its Complex with the Reaction Products Salicylate and Pyruvate.
J.Mol.Biol., 357, 2006
2QGH
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BU of 2qgh by Molmil
Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori complexed with L-lysine
分子名称: Diaminopimelate decarboxylase, GLYCEROL, LYSINE, ...
著者Hu, T, Wu, D, Jiang, H, Shen, X.
登録日2007-06-28
公開日2008-05-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori complexed with L-lysine
TO BE PUBLISHED
6UJ1
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BACE2 mutant in complex with a macrocyclic compound
分子名称: (3S)-3-hydroxy-N-(2-methylpropyl)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-L-norleucinamide, Beta-secretase 2
著者Yen, Y.C, Ghosh, A.K, Mesecar, A.D.
登録日2019-10-02
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors.
Acs Chem Neurosci, 12, 2021
2FQW
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BU of 2fqw by Molmil
PnrA from Treponema pallidum as purified from E. coli (bound to inosine)
分子名称: INOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
2QJZ
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Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1
分子名称: Microtubule-associated protein RP/EB family member 1
著者Slep, K.C, Vale, R.D.
登録日2007-07-09
公開日2007-10-02
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1.
Mol.Cell, 27, 2007
2FRK
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BU of 2frk by Molmil
Nitrosyl Horse Heart Myoglobin, Nitric Oxide Gas Method
分子名称: Myoglobin, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Copeland, D.M, Soares, A.S, West, A.H, Richter-Addo, G.B.
登録日2006-01-19
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
J.Inorg.Biochem., 100, 2006
6UCY
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BU of 6ucy by Molmil
Multi-conformer model of Ketosteroid Isomerase from Pseudomonas Putida (pKSI) bound to 4-Androstenedione at 250 K
分子名称: 4-ANDROSTENE-3-17-DIONE, CHLORIDE ION, MAGNESIUM ION, ...
著者Yabukarski, F, Herschlag, D, Biel, J.T, Fraser, J.S.
登録日2019-09-18
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles.
Proc.Natl.Acad.Sci.USA, 117, 2020
2QU7
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Crystal structure of a putative transcription regulator from Staphylococcus saprophyticus subsp. saprophyticus
分子名称: CHLORIDE ION, Putative transcriptional regulator
著者Bonanno, J.B, Freeman, J, Bain, K.T, Mendoza, M, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-08-03
公開日2007-08-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a putative transcription regulator from Staphylococcus saprophyticus subsp. saprophyticus.
To be Published
5EOQ
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BU of 5eoq by Molmil
Structure of the murine Fab 1G6 bound to the vaccinia virus A27 peptide 31-40
分子名称: Anti vaccinia virus A27 antibody Fab 1G6 heavy chain, Anti vaccinia virus A27 antibody Fab 1G6 light chain, Protein A27
著者Matho, M.H, Zajonc, D.M.
登録日2015-11-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
2QVE
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BU of 2qve by Molmil
Crystal Structure of SgTAM bound to mechanism based inhibitor
分子名称: (3R)-3-amino-2,2-difluoro-3-(4-hydroxyphenyl)propanoic acid, Tyrosine Aminomutase
著者Christianson, C.V, Montavon, T.J, Bruner, S.D.
登録日2007-08-08
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM
Bioorg.Med.Chem.Lett., 18, 2008
8UAU
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BU of 8uau by Molmil
human ATE1 in complex with Arg-tRNA and a peptide substrate
分子名称: Isoform ATE1-2 of Arginyl-tRNA--protein transferase 1, RNA (76-MER), ZINC ION, ...
著者Huang, W, Zhang, Y, Taylor, D.J.
登録日2023-09-22
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Nat Commun, 15, 2024
8TRU
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Crystal structure of a CE15 from Fibrobacter succinogenes subsp. succinogenes S85
分子名称: Glucuronyl esterase, ZINC ION
著者Gruninger, R.J, Jones, D.R.
登録日2023-08-10
公開日2024-08-28
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural, Biochemical, and Phylogenetic Analysis of Bacterial and Fungal Carbohydrate Esterase Family 15 Glucuronoyl Esterases in the Rumen.
Protein J., 43, 2024

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