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PDB: 52974 件

7T3X
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Structure of unphosphorylated Pediculus humanus (Ph) PINK1 D334A mutant
分子名称: Serine/threonine-protein kinase PINK1
著者Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D.
登録日2021-12-09
公開日2021-12-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.53 Å)
主引用文献Activation mechanism of PINK1.
Nature, 602, 2022
4IO8
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Crystal structure of human HSP70 complexed with 4-{(2R,3S,4R)-5-[(R)-6-Amino-8-(3,4-dichloro-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxymethyl}-benzonitrile
分子名称: 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Heat shock 70kDa protein 1A variant
著者Musil, D, Scholz, S.
登録日2013-01-07
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Functional analysis of hsp70 inhibitors.
Plos One, 8, 2013
7T44
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Structure of SARS-CoV-2 3CL protease in complex with inhibitor 4c
分子名称: (1R,2S)-2-[(N-{[(2-azaspiro[3.3]heptan-6-yl)oxy]carbonyl}-L-leucyl)amino]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-1-hydroxy-2-{[N-({[2-(methanesulfonyl)-2-azaspiro[3.3]heptan-6-yl]oxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ...
著者Liu, L, Lovell, S, Battaile, K.P, Chamandi, S.D, Kim, Y, Groutas, W.C, Chang, K.O.
登録日2021-12-09
公開日2021-12-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease.
J.Med.Chem., 65, 2022
3EFO
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Crystal Structure of the mammalian COPII-coat protein Sec23/24 bound to the transport signal sequence of syntaxin 5
分子名称: Peptide, Protein transport protein Sec23A, SEC24 related gene family, ...
著者Goldberg, J, Mancias, J.D.
登録日2008-09-09
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
Embo J., 27, 2008
4R60
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Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris
分子名称: MANGANESE (II) ION, PHOSPHATE ION, Proline dipeptidase, ...
著者Kumar, A, Ghosh, B, Are, V.N, Jamdar, S.N, Makde, R.D, Sharma, S.M.
登録日2014-08-22
公開日2014-09-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris
to be published
2IAH
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Crystal structure of the ferripyoverdine receptor of the outer membrane of Pseudomonas aeruginosa bound to ferripyoverdine.
分子名称: (1S)-1-CARBOXY-5-[(3-CARBOXYPROPANOYL)AMINO]-8,9-DIHYDROXY-1,2,3,4-TETRAHYDROPYRIMIDO[1,2-A]QUINOLIN-11-IUM, FE (III) ION, Ferripyoverdine receptor, ...
著者Wirth, C, Pattus, F, Cobessi, D.
登録日2006-09-08
公開日2007-09-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献From the periplasmic signaling domain to the extracellular face of an outer membrane signal transducer of Pseudomonas aeruginosa: crystal structure of the ferric pyoverdine outer membrane receptor.
J.Mol.Biol., 368, 2007
6W2Q
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Junction 34, DHR53-DHR4
分子名称: CALCIUM ION, Junction 34
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
7T4K
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Structure of dimeric phosphorylated Pediculus humanus (Ph) PINK1 with kinked alpha-C helix in chain B
分子名称: Serine/threonine-protein kinase PINK1, putative
著者Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D.
登録日2021-12-10
公開日2022-01-12
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Activation mechanism of PINK1.
Nature, 602, 2022
6W3D
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Rd1NTF2_05 with long sheet
分子名称: Rd1NTF2_05
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
7T4N
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Structure of dimeric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant
分子名称: Serine/threonine-protein kinase PINK1, putative
著者Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D.
登録日2021-12-10
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.35 Å)
主引用文献Activation mechanism of PINK1.
Nature, 602, 2022
6W2W
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Junction 24, DHR14-DHR18
分子名称: Junction 24 DHR14-DHR18
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
4QXP
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Crystal structure of hSTING(G230I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
7T4L
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BU of 7t4l by Molmil
Structure of dimeric phosphorylated Pediculus humanus (Ph) PINK1 with extended alpha-C helix in chain B
分子名称: Serine/threonine-protein kinase PINK1, putative
著者Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D.
登録日2021-12-10
公開日2022-01-12
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Activation mechanism of PINK1.
Nature, 602, 2022
6W9Q
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BU of 6w9q by Molmil
Peptide-bound SARS-CoV-2 Nsp9 RNA-replicase
分子名称: 3C-like proteinase peptide, Non-structural protein 9 fusion, PHOSPHATE ION
著者Littler, D.R, Gully, B.S, Riboldi-Tunnicliffe, A, Rossjohn, J.
登録日2020-03-23
公開日2020-04-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9.
Iscience, 23, 2020
6ITS
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BU of 6its by Molmil
The citrate-bound trimer of chemoreceptor MCP2201 ligand binding domain
分子名称: CITRIC ACID, Methyl-accepting chemotaxis sensory transducer
著者Hong, Y, Li, D.F.
登録日2018-11-26
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献The ligand-binding domain of a chemoreceptor from Comamonas testosteroni has a previously unknown homotrimeric structure.
Mol.Microbiol., 112, 2019
7TB6
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BU of 7tb6 by Molmil
Structure of S. maltophilia CapW
分子名称: S. maltophilia CapW, SULFATE ION
著者Blankenchip, C.L, Nguyen, J.V, Lau, R.K, Ye, Q, Corbett, K.D.
登録日2021-12-21
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Control of bacterial immune signaling by a WYL domain transcription factor.
Nucleic Acids Res., 50, 2022
7TB5
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Structure of P. aeruginosa PA17 CapW
分子名称: SULFATE ION, WYL domain-containing protein
著者Blankenchip, C.L, Nguyen, J.V, Lau, R.K, Ye, Q, Corbett, K.D.
登録日2021-12-21
公開日2022-01-19
最終更新日2022-06-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Control of bacterial immune signaling by a WYL domain transcription factor.
Nucleic Acids Res., 50, 2022
3ZRI
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BU of 3zri by Molmil
N-domain of ClpV from Vibrio cholerae
分子名称: CLPB PROTEIN
著者Lenherr, E.D, Kopp, J, Sinning, I.
登録日2011-06-16
公開日2011-06-29
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for the Unique Role of the Aaa+ Chaperone Clpv in Type Vi Protein Secretion.
J.Biol.Chem., 286, 2011
4QQS
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BU of 4qqs by Molmil
Crystal structure of a thermostable family-43 glycoside hydrolase
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycoside hydrolase family 43, SODIUM ION
著者Hassan, N, Kori, L.D, Patel, B.K.C, Divne, C, Tan, T.C.
登録日2014-06-29
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-resolution crystal structure of a polyextreme GH43 glycosidase from Halothermothrix orenii with alpha-L-arabinofuranosidase activity.
Acta Crystallogr F Struct Biol Commun, 71, 2015
4QPP
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The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE
分子名称: 2-{4-[3-chloro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl}-N-methylethanamine, POLY-UNK, Protein arginine N-methyltransferase 6, ...
著者Dong, A, Zeng, H, Smil, D, Walker, J.R, He, H, Eram, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
登録日2014-06-24
公開日2014-08-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421
To be Published
2HIP
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BU of 2hip by Molmil
THE MOLECULAR STRUCTURE OF THE HIGH POTENTIAL IRON-SULFUR PROTEIN ISOLATED FROM ECTOTHIORHODOSPIRA HALOPHILA DETERMINED AT 2.5-ANGSTROMS RESOLUTION
分子名称: HIGH POTENTIAL IRON SULFUR PROTEIN, IRON/SULFUR CLUSTER
著者Breiter, D.R, Meyer, T.E, Rayment, I, Holden, H.M.
登録日1991-06-24
公開日1992-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The molecular structure of the high potential iron-sulfur protein isolated from Ectothiorhodospira halophila determined at 2.5-A resolution.
J.Biol.Chem., 266, 1991
6IFF
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Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans
分子名称: SODIUM ION, TYROSINE, ZINC ION, ...
著者Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D.
登録日2018-09-20
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
7TGG
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Cryo-EM structure of PilA-N and PilA-C from Geobacter sulfurreducens
分子名称: Geopilin domain 1 protein, Geopilin domain 2 protein
著者Wang, F, Mustafa, K, Chan, C.H, Joshi, K, Bond, D.R, Hochbaum, A.I, Egelman, E.H.
登録日2022-01-07
公開日2022-02-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing.
Nat Microbiol, 7, 2022
6PQA
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GAVVGG segment 119-124 from human prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
4R04
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Clostridium difficile Toxin A (TcdA)
分子名称: Toxin A, ZINC ION
著者Lacy, D.B, Spiller, B.W, Rutherford, S.A.
登録日2014-07-29
公開日2016-01-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Glucosyl Transferase Structure
Nat Microbiol, 2016

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