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PDB: 1 results

5H7O
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BU of 5h7o by Molmil
Crystal structure of DJ-101 in complex with tubulin protein
Descriptor: 2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Arnst, K, Wang, Y, Hwang, D.-J, Xue, Y, Costello, T, Hamilton, D, Chen, Q, Yang, J, Park, F, Dalton, J.T, Miller, D.D, Li, W.
Deposit date:2016-11-20
Release date:2017-12-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Cancer Res., 78, 2018

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