8OVB
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7PI6
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7NBA
| Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | 登録日 | 2021-01-25 | 公開日 | 2021-10-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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7NB8
| Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | 登録日 | 2021-01-25 | 公開日 | 2021-10-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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7Z2A
| P. berghei kinesin-8B motor domain in no nucleotide state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-10-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7Z2B
| P. berghei kinesin-8B motor domain in AMPPNP state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-11-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7Z2C
| P. falciparum kinesin-8B motor domain in no nucleotide bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-10-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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6TIW
| Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-11-22 | 公開日 | 2020-03-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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6TA4
| Human kinesin-5 motor domain in the AMPPNP state bound to microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-10-29 | 公開日 | 2020-03-04 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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6TA3
| Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1) | 分子名称: | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... | 著者 | Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. | 登録日 | 2019-10-29 | 公開日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
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