4TXD
 
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5NKM
 | | SMG8-SMG9 complex | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Li, L, Basquin, J, Conti, E. | | 登録日 | 2017-03-31 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | | 主引用文献 | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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2C37
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1OL6
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5NKK
 | | SMG8-SMG9 complex GDP bound | | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Li, L, Basquin, J, Conti, E. | | 登録日 | 2017-03-31 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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2C38
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2C39
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7QE0
 | | 80S-bound human SKI complex in the open state | | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | | 登録日 | 2021-12-01 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
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1A0E
 | | XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA | | 分子名称: | COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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5C0X
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5C0W
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5MC6
 | | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-18 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
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7QDR
 | | Apo human SKI complex in the closed state | | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | | 登録日 | 2021-11-29 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
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7QDS
 | | Apo human SKI complex in the open state | | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | | 著者 | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | | 登録日 | 2021-11-30 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
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5C0Y
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7PW6
 | | Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | | 著者 | Langer, L.M, Conti, E. | | 登録日 | 2021-10-06 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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5AOR
 | | Structure of MLE RNA ADP AlF4 complex | | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | 著者 | Prabu, J.R, Conti, E. | | 登録日 | 2015-09-11 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | 著者 | Basquin, J, Oezguer, S, Conti, E. | | 登録日 | 2015-09-08 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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5LXY
 | | Structure of the minimal RBM7 - ZCCHC8 Complex | | 分子名称: | BROMIDE ION, RNA-binding protein 7, Zinc finger CCHC domain-containing protein 8 | | 著者 | Falk, S, Finogenova, K, Benda, C, Conti, E. | | 登録日 | 2016-09-23 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
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1HL6
 | | A novel mode of RBD-protein recognition in the Y14-mago complex | | 分子名称: | CG8781 PROTEIN, MAGO NASHI PROTEIN | | 著者 | Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E. | | 登録日 | 2003-03-13 | | 公開日 | 2003-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
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5MZN
 | | Helicase Sen1 | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Leonaite, B, Basquin, J, Conti, E. | | 登録日 | 2017-02-01 | | 公開日 | 2017-04-19 | | 最終更新日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | | 主引用文献 | Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family.
EMBO J., 36, 2017
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5LXR
 | | Structure of the minimal RBM7 - ZCCHC8 Complex | | 分子名称: | BROMIDE ION, CHLORIDE ION, RNA-binding protein 7, ... | | 著者 | Falk, S, Finogenova, K, Benda, C, Conti, E. | | 登録日 | 2016-09-22 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
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1JN5
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor | | 分子名称: | FG-repeat, TAP, p15 | | 著者 | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | 登録日 | 2001-07-23 | | 公開日 | 2001-10-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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1JKG
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor | | 分子名称: | TAP, p15 | | 著者 | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | 登録日 | 2001-07-12 | | 公開日 | 2001-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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2VNU
 | | Crystal structure of Sc Rrp44 | | 分子名称: | 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP)-3', EXOSOME COMPLEX EXONUCLEASE RRP44, MAGNESIUM ION, ... | | 著者 | Lorentzen, E, Basquin, J, Conti, E. | | 登録日 | 2008-02-07 | | 公開日 | 2008-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the Rnase II Nuclease Family
Mol.Cell, 29, 2008
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