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PDB: 155 件
5NKM
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BU of 5nkm by Molmil
SMG8-SMG9 complex
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Li, L, Basquin, J, Conti, E.
登録日2017-03-31
公開日2017-04-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
4Q8H
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BU of 4q8h by Molmil
Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase-RNase module
分子名称: MAGNESIUM ION, PAB-dependent poly(A)-specific ribonuclease subunit PAN2
著者Schaefer, I.B, Conti, E.
登録日2014-04-27
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat.Struct.Mol.Biol., 21, 2014
2BR2
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BU of 2br2 by Molmil
RNase PH core of the archaeal exosome
分子名称: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2
著者lorentzen, E, Fribourg, S, Conti, E.
登録日2005-04-30
公開日2005-06-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits.
Nat.Struct.Mol.Biol., 12, 2005
5OKZ
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BU of 5okz by Molmil
Crystal Strucrure of the Mpp6 Exosome complex
分子名称: CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ...
著者Falk, S, Ebert, J, Conti, E.
登録日2017-07-26
公開日2017-08-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.200039 Å)
主引用文献Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Cell Rep, 20, 2017
4XR7
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BU of 4xr7 by Molmil
Structure of the Saccharomyces cerevisiae PAN2-PAN3 core complex
分子名称: PAB-dependent poly(A)-specific ribonuclease subunit PAN2, PAB-dependent poly(A)-specific ribonuclease subunit PAN3
著者Schafer, I.B, Rode, M, Bonneau, F, Schussler, S, Conti, E.
登録日2015-01-20
公開日2015-01-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.796 Å)
主引用文献The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat. Struct. Mol. Biol., 21, 2014
3FHC
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BU of 3fhc by Molmil
Crystal structure of human Dbp5 in complex with Nup214
分子名称: ATP-dependent RNA helicase DDX19B, Nuclear pore complex protein Nup214
著者von Moeller, H, Conti, E.
登録日2008-12-09
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
Nat.Struct.Mol.Biol., 16, 2009
8BFJ
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BU of 8bfj by Molmil
CNOT11-GGNBP2 complex
分子名称: 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
4IFD
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BU of 4ifd by Molmil
Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Exosome complex component CSL4, ...
著者Makino, D.L, Conti, E.
登録日2012-12-14
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
Nature, 495, 2013
2C37
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BU of 2c37 by Molmil
RNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA
分子名称: 5-O-phosphono-beta-D-ribofuranose, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
著者Lorentzen, E, Conti, E.
登録日2005-10-04
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
2C38
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BU of 2c38 by Molmil
RNase PH core of the archaeal exosome in complex with A5 RNA
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
著者Lorentzen, E, Conti, E.
登録日2005-10-04
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
1A0E
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BU of 1a0e by Molmil
XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA
分子名称: COBALT (II) ION, XYLOSE ISOMERASE
著者Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D.
登録日1997-11-28
公開日1998-06-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
2C39
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BU of 2c39 by Molmil
RNase PH core of the archaeal exosome in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, PROBABLE EXOSOME COMPLEX EXONUCLEASE 2
著者Lorentzen, E, Conti, E.
登録日2005-10-05
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
5LXY
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BU of 5lxy by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
分子名称: BROMIDE ION, RNA-binding protein 7, Zinc finger CCHC domain-containing protein 8
著者Falk, S, Finogenova, K, Benda, C, Conti, E.
登録日2016-09-23
公開日2016-12-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
4JHJ
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BU of 4jhj by Molmil
Crystal structure of Danio rerio Slip1 in complex with Dbp5
分子名称: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast), MIF4G domain-containing protein B
著者Von Moeller, H, Conti, E.
登録日2013-03-05
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
Nucleic Acids Res., 41, 2013
4WFC
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BU of 4wfc by Molmil
Structure of the Rrp6-Rrp47 interaction
分子名称: Exosome complex exonuclease RRP6, Exosome complex protein LRP1, SULFATE ION
著者Schuch, B, Conti, E.
登録日2014-09-14
公開日2014-10-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.
Embo J., 33, 2014
2XZL
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BU of 2xzl by Molmil
Upf1-RNA complex
分子名称: 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HELICASE NAM7, ...
著者Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
登録日2010-11-26
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZP
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BU of 2xzp by Molmil
Upf1 helicase
分子名称: GLYCEROL, MALONATE ION, REGULATOR OF NONSENSE TRANSCRIPTS 1
著者Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
登録日2010-11-26
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
5LXR
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BU of 5lxr by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
分子名称: BROMIDE ION, CHLORIDE ION, RNA-binding protein 7, ...
著者Falk, S, Finogenova, K, Benda, C, Conti, E.
登録日2016-09-22
公開日2016-12-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
5MZN
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BU of 5mzn by Molmil
Helicase Sen1
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Leonaite, B, Basquin, J, Conti, E.
登録日2017-02-01
公開日2017-04-19
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family.
EMBO J., 36, 2017
4JHK
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BU of 4jhk by Molmil
Crystal structure of Danio rerio SLIP1 in complex with SLBP
分子名称: MIF4G domain-containing protein B, SULFATE ION, Sb:cb157 protein
著者von Moeller, H, Conti, E.
登録日2013-03-05
公開日2013-07-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.507 Å)
主引用文献Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.
Nucleic Acids Res., 41, 2013
5OOQ
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BU of 5ooq by Molmil
Structure of the Mtr4 Nop53 Complex
分子名称: ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION
著者Falk, S, Basquin, J, Conti, E.
登録日2017-08-08
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
1OF5
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BU of 1of5 by Molmil
Crystal structure of Mex67-Mtr2
分子名称: MERCURY (II) ION, MRNA EXPORT FACTOR MEX67, MRNA TRANSPORT REGULATOR MTR2
著者Fribourg, S, Conti, E.
登録日2003-04-08
公開日2003-07-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15.
EMBO Rep., 4, 2003
1OL7
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BU of 1ol7 by Molmil
Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SERINE/THREONINE KINASE 6
著者Bayliss, R, Conti, E.
登録日2003-08-06
公開日2003-10-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OL5
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Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ...
著者Bayliss, R, Conti, E.
登録日2003-08-06
公開日2003-10-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
8BFI
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BU of 8bfi by Molmil
human CNOT1-CNOT10-CNOT11 module
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2023-02-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023

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