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PDB: 12 件

5JJQ
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Crystal structure of IdnL1
分子名称: 5'-O-[(R)-{[(3S)-3-aminobutanoyl]oxy}(hydroxy)phosphoryl]adenosine, AMP-dependent synthetase and ligase, CHLORIDE ION
著者Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2016-04-25
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Biochemical characterization and structural insight into aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6
Proteins, 85, 2017
5JJP
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Crystal structure of CmiS6
分子名称: Nonribosomal peptide synthase
著者Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2016-04-25
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical characterization and structural insight into aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6
Proteins, 85, 2017
6AKD
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Crystal structure of IdnL7
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, AMP-dependent synthetase and ligase, GLYCEROL
著者Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2018-08-31
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis.
Acta Crystallogr F Struct Biol Commun, 75, 2019
3IFX
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Crystal structure of the Spin-labeled KcsA mutant V48R1
分子名称: POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, TETRABUTYLAMMONIUM ION, ...
著者Cieslak, J.A, Focia, P.J, Gross, A.
登録日2009-07-26
公開日2010-02-09
最終更新日2023-09-06
実験手法EPR (3.56 Å), X-RAY DIFFRACTION
主引用文献Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel
Biochemistry, 49, 2010
4E5O
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Crystal structure of mouse thymidylate synthase in complex with dUMP
分子名称: 1,4-BUTANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
著者Dowiercial, A, Jarmula, A, Rypniewski, W, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W.
登録日2012-03-14
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme
Struct Chem, 2016
3IHI
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BU of 3ihi by Molmil
Crystal structure of mouse thymidylate synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Dowiercial, A, Jarmula, A, Rypniewski, W.R, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W.
登録日2009-07-30
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme
Struct Chem, 2016
2TSR
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BU of 2tsr by Molmil
THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
著者Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R.
登録日1998-06-19
公開日1999-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
1TLC
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BU of 1tlc by Molmil
THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, THYMIDYLATE SYNTHASE
著者Weichsel, A, Montfort, W.R, Ciesla, J, Maley, F.
登録日1995-03-07
公開日1995-06-03
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89.
Proc.Natl.Acad.Sci.USA, 92, 1995
1RTS
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BU of 1rts by Molmil
THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
著者Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R.
登録日1998-06-19
公開日1999-02-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
3WV5
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BU of 3wv5 by Molmil
Complex structure of VinN with 3-methylaspartate
分子名称: (2S,3S)-3-methyl-aspartic acid, Non-ribosomal peptide synthetase
著者Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T.
登録日2014-05-15
公開日2014-10-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism
J.Biol.Chem., 289, 2014
3WV4
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Crystal structure of VinN
分子名称: Non-ribosomal peptide synthetase
著者Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T.
登録日2014-05-15
公開日2014-10-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism
J.Biol.Chem., 289, 2014
3WVN
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Complex structure of VinN with L-aspartate
分子名称: ASPARTIC ACID, Non-ribosomal peptide synthetase
著者Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T.
登録日2014-05-30
公開日2014-10-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism
J.Biol.Chem., 289, 2014

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