5JJQ
| Crystal structure of IdnL1 | 分子名称: | 5'-O-[(R)-{[(3S)-3-aminobutanoyl]oxy}(hydroxy)phosphoryl]adenosine, AMP-dependent synthetase and ligase, CHLORIDE ION | 著者 | Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T. | 登録日 | 2016-04-25 | 公開日 | 2017-03-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Biochemical characterization and structural insight into aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6 Proteins, 85, 2017
|
|
5JJP
| |
6AKD
| Crystal structure of IdnL7 | 分子名称: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, AMP-dependent synthetase and ligase, GLYCEROL | 著者 | Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T. | 登録日 | 2018-08-31 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis. Acta Crystallogr F Struct Biol Commun, 75, 2019
|
|
3IFX
| Crystal structure of the Spin-labeled KcsA mutant V48R1 | 分子名称: | POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, TETRABUTYLAMMONIUM ION, ... | 著者 | Cieslak, J.A, Focia, P.J, Gross, A. | 登録日 | 2009-07-26 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | EPR (3.56 Å), X-RAY DIFFRACTION | 主引用文献 | Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel Biochemistry, 49, 2010
|
|
4E5O
| Crystal structure of mouse thymidylate synthase in complex with dUMP | 分子名称: | 1,4-BUTANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | 著者 | Dowiercial, A, Jarmula, A, Rypniewski, W, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W. | 登録日 | 2012-03-14 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme Struct Chem, 2016
|
|
3IHI
| Crystal structure of mouse thymidylate synthase | 分子名称: | SULFATE ION, Thymidylate synthase | 著者 | Dowiercial, A, Jarmula, A, Rypniewski, W.R, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W. | 登録日 | 2009-07-30 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme Struct Chem, 2016
|
|
2TSR
| THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | 登録日 | 1998-06-19 | 公開日 | 1999-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
|
|
1TLC
| THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89 | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, THYMIDYLATE SYNTHASE | 著者 | Weichsel, A, Montfort, W.R, Ciesla, J, Maley, F. | 登録日 | 1995-03-07 | 公開日 | 1995-06-03 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc.Natl.Acad.Sci.USA, 92, 1995
|
|
1RTS
| THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | 登録日 | 1998-06-19 | 公開日 | 1999-02-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
|
|
3WV5
| Complex structure of VinN with 3-methylaspartate | 分子名称: | (2S,3S)-3-methyl-aspartic acid, Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-15 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
|
|
3WV4
| Crystal structure of VinN | 分子名称: | Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-15 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
|
|
3WVN
| Complex structure of VinN with L-aspartate | 分子名称: | ASPARTIC ACID, Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-30 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
|
|