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PDB: 304 件

4GQ3
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Human menin with bound inhibitor MI-2
分子名称: 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, Menin, ...
著者Shi, A, Murai, M.J, He, S, Lund, G.L, Hartley, T, Purohit, T, Reddy, G, Chruszcz, M, Grembecka, J, Cierpicki, T.
登録日2012-08-22
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.
Blood, 120, 2012
4GQ4
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Human menin with bound inhibitor MI-2-2
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine, ...
著者Shi, A, Murai, M.J, He, S, Lund, G.L, Hartley, T, Purohit, T, Reddy, G, Chruszcz, M, Grembecka, J, Cierpicki, T.
登録日2012-08-22
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.
Blood, 120, 2012
4GQ6
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Human menin in complex with MLL peptide
分子名称: Histone-lysine N-methyltransferase MLL, Menin, PENTAETHYLENE GLYCOL, ...
著者Shi, A, Murai, M.J, He, S, Lund, G.L, Hartley, T, Purohit, T, Reddy, G, Chruszcz, M, Grembecka, J, Cierpicki, T.
登録日2012-08-22
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.
Blood, 120, 2012
8VY6
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Murine light chain dimer
分子名称: 6A8 light chain, SULFATE ION
著者Kapingidza, A.B, Dolamore, C, Hyduke, N.P, Easly, W, Chivv, C, Pomes, A, Chruszcz, M.
登録日2024-02-07
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural, Biophysical, and Computational Studies of a Murine Light Chain Dimer
Molecules, 29, 2024
6MBX
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CRYSTAL STRUCTURE OF MUSKMELON ALLERGEN CUC M 2
分子名称: Profilin
著者Kapingidza, A.B, Hyduke, N.P, Chruszcz, M.
登録日2018-08-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins.
Mol.Immunol., 114, 2019
6XO2
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Structural Characterization of Beta Cyanoalanine Synthase from Tetranychus Urticae (two-spotted spider mite)
分子名称: ACETATE ION, Beta-cyanoalanine synthase, PYRIDOXAL-5'-PHOSPHATE
著者Daneshian, L, Schlachter, C, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2020-07-06
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional characterization of beta-cyanoalanine synthase from Tetranychus urticae.
Insect Biochem.Mol.Biol., 142, 2022
1UXO
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The crystal structure of the ydeN gene product from B. subtilis
分子名称: Putative hydrolase YdeN
著者Janda, I.K, Devedjiev, Y, Cooper, D.R, Chruszcz, M, Derewenda, U, Gabrys, A, Minor, W, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG)
登録日2004-02-27
公開日2004-05-27
最終更新日2022-05-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution.
Acta Crystallogr. D Biol. Crystallogr., 60, 2004
6OY4
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Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1
分子名称: Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ...
著者Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M.
登録日2019-05-14
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
7MLH
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Crystal structure of human IgE (2F10) in complex with Der p 2.0103
分子名称: CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ...
著者Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M.
登録日2021-04-28
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo.
Pnas Nexus, 1, 2022
7MFJ
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Structural Characterization of Beta Cyanoalanine Synthase from Tetranychus Urticae
分子名称: ACETATE ION, Beta-cyanoalanine synthase, PYRIDOXAL-5'-PHOSPHATE
著者Daneshian, L, Schlachter, C, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2021-04-09
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Structural and functional characterization of beta-cyanoalanine synthase from Tetranychus urticae.
Insect Biochem.Mol.Biol., 142, 2022
2RD7
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BU of 2rd7 by Molmil
Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins
分子名称: CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain
著者Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M.
登録日2007-09-21
公開日2008-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
3LNL
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Crystal structure of Staphylococcus aureus protein SA1388
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UPF0135 protein SA1388, ZINC ION
著者Singh, K.S, Chruszcz, M, Zhang, X, Minor, W, Zhang, H.
登録日2010-02-02
公開日2010-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a Conserved Hypothetical Protein Sa1388 from S. aureus Reveals a Capped Hexameric Toroid with Two Pii Domain Lids and a Dinuclear Metal Center.
Bmc Struct.Biol., 6, 2006
7MCO
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BU of 7mco by Molmil
Crystal Structure of Tetur04g02350
分子名称: UDP-glycosyltransferase 203A2, URIDINE-5'-DIPHOSPHATE
著者Danehsian, L, Kluza, A, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2021-04-02
公開日2022-04-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Tetur04g02350
To Be Published
1Z77
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BU of 1z77 by Molmil
Crystal structure of transcriptional regulator protein from Thermotoga maritima.
分子名称: 1,2-ETHANEDIOL, transcriptional regulator (TetR family)
著者Koclega, K.D, Chruszcz, M, Zimmerman, M.D, Cymborowski, M, Kudritska, M, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2005-03-24
公開日2005-05-10
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment.
J.Struct.Biol., 159, 2007
6PMU
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BU of 6pmu by Molmil
Structural Characterization of Beta Cyanoalanine Synthase from Tetranychus Urticae
分子名称: Beta-cyanoalanine synthase, PYRIDOXAL-5'-PHOSPHATE
著者Daneshian, L, Schlachter, C, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2019-07-02
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterization of Beta Cyanoalanine Synthase from Tetranychus Urticae
To Be Published
1Y89
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Crystal Structure of devB protein
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, DI(HYDROXYETHYL)ETHER, NONAETHYLENE GLYCOL, ...
著者Lazarski, K, Cymborowski, M, Chruszcz, M, Zheng, H, Zhang, R, Lezondra, L, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2004-12-10
公開日2005-01-25
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of devB protein
To be Published
6PNT
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Structural Characterization of UDP-glycosyltransferase from Tetranychus Urticae
分子名称: UDP-glycosyltransferase 202A2
著者Daneshian, L, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2019-07-03
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Characterization of UDP-glycosyltransferase from Tetranychus Urticae
To Be Published
6V8S
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Crystal structure of Ara h 8.0201
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, Ara h 8 allergen isoform, SULFATE ION
著者Pote, S, Offermann, L.R, Hurlburt, B.K, McBride, J.K, Chruszcz, M.
登録日2019-12-12
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ara h 8.0201
To Be Published
8STX
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Crystal structure of the F337A mutation of Trypanosoma cruzi glucokinase in the apo form (open conformation)
分子名称: Glucokinase
著者Abiskaroon, B, Carey, S.M, D'Antonio, E.L, Chruszcz, M.
登録日2023-05-11
公開日2023-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 337.
Biochimie, 218, 2023
4X9U
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Crystal structure of the kiwifruit allergen Act d 5
分子名称: Kiwellin
著者Offermann, L.R, Perdue, M.L, Giangrieco, I, Tamburrini, M, Ciardiello, M.A, Chruszcz, M.
登録日2014-12-11
公開日2015-07-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Elusive Structural, Functional, and Immunological Features of Act d 5, the Green Kiwifruit Kiwellin.
J.Agric.Food Chem., 63, 2015
4DGT
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BU of 4dgt by Molmil
Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate
分子名称: CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
著者Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-01-26
公開日2012-02-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of putative aminotransferase from Clostridium difficile 630
to be published
4DQ6
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Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630
分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Putative pyridoxal phosphate-dependent transferase
著者Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-02-15
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of putative aminotransferase from Clostridium difficile 630
to be published
4EUY
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Crystal structure of thioredoxin-like protein BCE_0499 from Bacillus cereus ATCC 10987
分子名称: Uncharacterized protein
著者Shabalin, I.G, Kagan, O, Chruszcz, M, Grabowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2012-04-25
公開日2012-05-16
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of thioredoxin-like protein BCE_0499 from Bacillus cereus
To be Published
4XUW
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Structure of the hazelnut allergen, Cor a 8
分子名称: Non-specific lipid-transfer protein, PHOSPHATE ION
著者Offermann, L.R, Perdue, M.L, Bublin, M, Pfeifer, S, Dubiela, P, Hoffmann-Sommergruber, K, Chruszcz, M.
登録日2015-01-26
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural and Functional Characterization of the Hazelnut Allergen Cor a 8.
J.Agric.Food Chem., 63, 2015
4X9K
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Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, GLYCEROL, MALONATE ION, ...
著者Hou, J, Chruszcz, M, Zheng, H, Grabowski, M, Chordia, M.D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-12-11
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural and enzymatic studies of beta-ketoacyl-(acyl carrier protein) synthase III (FabH) from Vibrio cholerae
to be published

222036

件を2024-07-03に公開中

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