2WAW
 
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2WEE
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2WE9
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2WE7
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5BMU
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6WI7
 | | RING1B-BMI1 fusion in closed conformation | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimera, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2020-04-08 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
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6WI8
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5VNB
 | | YEATS in complex with histone H3 | | 分子名称: | 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2017-04-29 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
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5VNA
 | | Crystal structure of human YEATS domain | | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2017-04-29 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
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5YZI
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5YZH
 | | Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase | | 分子名称: | GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cho, H.J, Kang, B.S. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione.
J. Biol. Inorg. Chem., 23, 2018
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8YJX
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6KQQ
 | | NSD1 SET domain in complex with BT3 and SAM | | 分子名称: | 2-azanyl-6-[(2-azanyl-4-oxidanyl-1,3-benzothiazol-6-yl)disulfanyl]-1,3-benzothiazol-4-ol, 2-azanyl-6-sulfanyl-1,3-benzothiazol-4-ol, CALCIUM ION, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2019-08-18 | | 公開日 | 2020-09-02 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Covalent inhibition of NSD1 histone methyltransferase.
Nat.Chem.Biol., 16, 2020
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6KQP
 | | NSD1 SET domain in complex with SAM | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, S-ADENOSYLMETHIONINE, ... | | 著者 | Cho, H.J, Cierpicki, T. | | 登録日 | 2019-08-18 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Covalent inhibition of NSD1 histone methyltransferase.
Nat.Chem.Biol., 16, 2020
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7XKI
 | | Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry) | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562 | | 著者 | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | | 登録日 | 2022-04-19 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
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7XKT
 | | Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | | 登録日 | 2022-04-20 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
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5AIZ
 | | The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T-cell development and leukemia | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Cho, H.J, Murai, M, Chiang, M, Cierpicki, T. | | 登録日 | 2015-02-18 | | 公開日 | 2015-10-28 | | 最終更新日 | 2015-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Pias-Like Coactivator Zmiz1 is a Direct and Selective Cofactor of Notch1 in T-Cell Development and Leukemia
Immunity, 43, 2015
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2WL3
 | | crystal structure of catechol 2,3-dioxygenase | | 分子名称: | CALCIUM ION, CATECHOL 2,3-DIOXYGENASE, FE (III) ION, ... | | 著者 | Cho, H.J, Kim, K.J, Kang, B.S. | | 登録日 | 2009-06-21 | | 公開日 | 2010-09-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Substrate-Binding Mechanism of a Type I Extradiol Dioxygenase.
J.Biol.Chem., 285, 2010
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2WL9
 | | Crystal structure of catechol 2,3-dioxygenase | | 分子名称: | 3-METHYLCATECHOL, CATECHOL 2,3-DIOXYGENASE, FE (III) ION, ... | | 著者 | Cho, H.J, Kim, K.J, Kang, B.S. | | 登録日 | 2009-06-23 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Substrate-Binding Mechanism of a Type I Extradiol Dioxygenase.
J.Biol.Chem., 285, 2010
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2XVE
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2XVI
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2XVJ
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2XVF
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2XVH
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2WE8
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