1EW0
| CRYSTAL STRUCTURE ANALYSIS OF THE SENSOR DOMAIN OF RMFIXL(FERROUS FORM) | Descriptor: | FIXL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y. | Deposit date: | 2000-04-21 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies J.MOL.BIOL., 301, 2000
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6GYK
| Structure of a yeast closed complex (core CC1) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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1HLV
| CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA | Descriptor: | CENP-B BOX DNA, MAJOR CENTROMERE AUTOANTIGEN B | Authors: | Tanaka, Y, Nureki, O, Kurumizaka, H, Fukai, S, Kawaguchi, S, Ikuta, M, Iwahara, J, Okazaki, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2000-12-04 | Release date: | 2002-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA. EMBO J., 20, 2001
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6GYL
| Structure of a yeast closed complex with distorted DNA (core CCdist) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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1JFC
| X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferrous CO state at atomic resolution | Descriptor: | CARBON MONOXIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-06-20 | Release date: | 2001-12-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
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3ZFL
| Crystal structure of the V58A mutant of human class alpha glutathione transferase in the apo form | Descriptor: | GLUTATHIONE S-TRANSFERASE A1 | Authors: | Parbhoo, N, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. | Deposit date: | 2012-12-12 | Release date: | 2012-12-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal Structure of the V58A Mutant of Human Class Alpha Glutathione Transferase in the Apo Form To be Published
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3ZFB
| Crystal structure of the I75A mutant of human class alpha glutathione transferase in the apo form | Descriptor: | GLUTATHIONE S-TRANSFERASE A1 | Authors: | Parbhoo, N, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. | Deposit date: | 2012-12-11 | Release date: | 2012-12-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure of the I75A Mutant of Human Class Alpha Glutathione Transferase in the Apo Form To be Published
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4IQA
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1HRF
| SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4 | Descriptor: | HEREGULIN ALPHA | Authors: | Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F. | Deposit date: | 1994-07-21 | Release date: | 1994-10-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. EMBO J., 13, 1994
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1ISE
| Crystal structure of a mutant of ribosome recycling factor from Escherichia coli, Arg132Gly | Descriptor: | Ribosome Recycling Factor | Authors: | Nakano, H, Yoshida, T, Oka, S, Uchiyama, S, Nishina, K, Ohkubo, T, Kato, H, Yamagata, Y, Kobayashi, Y. | Deposit date: | 2001-11-30 | Release date: | 2003-10-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a mutant of ribosome recycling factor from Escherichia coli, Arg132Gly To be Published
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7B88
| Crystal structure of Retinoic Acid Receptor alpha (RXRA) in complexed with S99 inhibitor | Descriptor: | 3-[5-[3,5-bis(chloranyl)phenyl]-4-phenyl-1,3-oxazol-2-yl]propanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | Authors: | Chaikuad, A, Schierle, S, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-12 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics. J.Med.Chem., 64, 2021
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5Y4N
| Crystal structure of aerobically purified and anaerobically crystallized D. vulgaris Miyazaki F [NiFe]-hydrogenase | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Nishikawa, K, Mochida, S, Hiromoto, T, Shibata, N, Higuchi, Y. | Deposit date: | 2017-08-04 | Release date: | 2018-08-08 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. J.Inorg.Biochem., 177, 2017
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4P66
| Electrostatics of Active Site Microenvironments of E. coli DHFR | Descriptor: | CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ... | Authors: | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | Deposit date: | 2014-03-21 | Release date: | 2014-07-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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3KTL
| Crystal Structure of an I71A human GSTA1-1 mutant in complex with S-hexylglutathione | Descriptor: | Glutathione S-transferase A1, S-HEXYLGLUTATHIONE | Authors: | Achilonu, I.A, Gildenhuys, S, Fernandes, M.A, Fanucchi, S, Dirr, H.W. | Deposit date: | 2009-11-25 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function. Acta Crystallogr.,Sect.F, 66, 2010
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2NOO
| Crystal Structure of Mutant NikA | Descriptor: | IODIDE ION, NICKEL (II) ION, Nickel-binding periplasmic protein | Authors: | Addy, C, Ohara, M, Kawai, F, Kidera, A, Ikeguchi, M, Fuchigami, S, Osawa, M, Shimada, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. | Deposit date: | 2006-10-26 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Nickel binding to NikA: an additional binding site reconciles spectroscopy, calorimetry and crystallography. Acta Crystallogr.,Sect.D, 63, 2007
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7B9O
| Crystal structure of Retinoic Acid Receptor alpha (RXRA) in complexed with S169 inhibitor | Descriptor: | 3-(5-(3,5-bis(trifluoromethyl)phenyl)-4-phenyloxazol-2-yl)propanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | Authors: | Ni, X, Chaikuad, A, Schierle, S, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-14 | Release date: | 2021-02-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics. J.Med.Chem., 64, 2021
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4P68
| Electrostatics of Active Site Microenvironments for E. coli DHFR | Descriptor: | ACETATE ION, CALCIUM ION, Dihydrofolate reductase, ... | Authors: | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | Deposit date: | 2014-03-22 | Release date: | 2014-07-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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3G61
| Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | Descriptor: | (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a | Authors: | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | Deposit date: | 2009-02-05 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.35 Å) | Cite: | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
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1D06
| STRUCTURAL BASIS OF DIMERIZATION AND SENSORY MECHANISMS OF OXYGEN-SENSING DOMAIN OF RHIZOBIUM MELILOTI FIXL DETERMINED AT 1.4A RESOLUTION | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, nitrogen fixation regulatory protein fixL | Authors: | Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y. | Deposit date: | 1999-09-09 | Release date: | 2000-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies J.MOL.BIOL., 301, 2000
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1HRE
| SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4 | Descriptor: | HEREGULIN ALPHA | Authors: | Nagata, K, Kohda, D, Hatanaka, H, Ichikawa, S, Inagaki, F. | Deposit date: | 1994-07-21 | Release date: | 1994-10-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. EMBO J., 13, 1994
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1HS5
| NMR SOLUTION STRUCTURE OF DESIGNED P53 DIMER | Descriptor: | CELLULAR TUMOR ANTIGEN P53 | Authors: | Davison, T.S, Nie, X, Ma, W, Li, Y, Kay, C, Benchimol, S, Arrowsmith, C.H. | Deposit date: | 2000-12-22 | Release date: | 2001-01-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and functionality of a designed p53 dimer. J.Mol.Biol., 307, 2001
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5XLF
| Crystal structure of aerobically purified and aerobically crystallized D. vulgaris Miyazaki F [NiFe]-hydrogenase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Nishikawa, K, Mochida, S, Hiromoto, T, Shibata, N, Higuchi, Y. | Deposit date: | 2017-05-10 | Release date: | 2018-06-06 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. J. Inorg. Biochem., 177, 2017
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5XLG
| Crystal structure of anaerobically purified and aerobically crystallized D. vulgaris Miyazaki F [NiFe]-hydrogenase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE3-S4 CLUSTER, ... | Authors: | Nishikawa, K, Mochida, S, Hiromoto, T, Shibata, N, Higuchi, Y. | Deposit date: | 2017-05-10 | Release date: | 2018-06-06 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. J. Inorg. Biochem., 177, 2017
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5XLH
| Crystal structure of aerobically purified and aerobically crystallized for 12weeks D. vulgaris Miyazaki F [NiFe]-hydrogenase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Nishikawa, K, Mochida, S, Hiromoto, T, Shibata, N, Higuchi, Y. | Deposit date: | 2017-05-10 | Release date: | 2018-06-06 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. J. Inorg. Biochem., 177, 2017
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5XLE
| Crystal structure of anaerobically purified and anaerobically crystallized D. vulgaris Miyazaki F [NiFe]-hydrogenase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE3-S4 CLUSTER, ... | Authors: | Nishikawa, K, Mochida, S, Hiromoto, T, Shibata, N, Higuchi, Y. | Deposit date: | 2017-05-10 | Release date: | 2018-06-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. J. Inorg. Biochem., 177, 2017
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