3QG2
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![BU of 3qg2 by Molmil](/molmil-images/mine/3qg2) | Plasmodium falciparum DHFR-TS qradruple mutant (N51I+C59R+S108N+I164L, V1/S) pyrimethamine complex | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Vanichtanankul, J, Yuvaniyama, J, Taweechai, S, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y. | 登録日 | 2011-01-24 | 公開日 | 2011-06-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Trypanosomal dihydrofolate reductase reveals natural antifolate resistance Acs Chem.Biol., 6, 2011
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1Z7Z
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![BU of 1z7z by Molmil](/molmil-images/mine/1z7z) | Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule-1, human coxsackievirus A21 | 著者 | Xiao, C, Bator-Kelly, C.M, Rieder, E, Chipman, P.R, Craig, A, Kuhn, R.J, Wimmer, E, Rossmann, M.G. | 登録日 | 2005-03-28 | 公開日 | 2005-08-02 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | The crystal structure of coxsackievirus a21 and its interaction with icam-1. Structure, 13, 2005
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1Z7S
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![BU of 1z7s by Molmil](/molmil-images/mine/1z7s) | The crystal structure of coxsackievirus A21 | 分子名称: | CALCIUM ION, GUANOSINE-5'-MONOPHOSPHATE, Human COXSACKIEVIRUS A21, ... | 著者 | Xiao, C, Bator-Kelly, C.M, Rieder, E, Chipman, P.R, Craig, A, Kuhn, R.J, Wimmer, E, Rossmann, M.G. | 登録日 | 2005-03-28 | 公開日 | 2005-08-02 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The crystal structure of coxsackievirus a21 and its interaction with icam-1. Structure, 13, 2005
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1TXX
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1R6T
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![BU of 1r6t by Molmil](/molmil-images/mine/1r6t) | crystal structure of human tryptophanyl-tRNA synthetase | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | 登録日 | 2003-10-16 | 公開日 | 2004-01-06 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains Proc.Natl.Acad.Sci.USA, 100, 2003
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1R6U
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![BU of 1r6u by Molmil](/molmil-images/mine/1r6u) | Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | 登録日 | 2003-10-16 | 公開日 | 2004-01-06 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase Structure, 15, 2007
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1Q5V
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![BU of 1q5v by Molmil](/molmil-images/mine/1q5v) | Apo-NikR | 分子名称: | Nickel responsive regulator | 著者 | Schreiter, E.R, Sintchak, M.D, Guo, Y, Chivers, P.T, Sauer, R.T, Drennan, C.L. | 登録日 | 2003-08-11 | 公開日 | 2003-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the Nickel-Responsive Transcription Factor NikR Nat.Struct.Biol., 10, 2003
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3QFX
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![BU of 3qfx by Molmil](/molmil-images/mine/3qfx) | Trypanosoma brucei dihydrofolate reductase pyrimethamine complex | 分子名称: | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Vanichtanankul, J, Yuvaniyama, J, Taweechai, S, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y. | 登録日 | 2011-01-24 | 公開日 | 2011-06-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Trypanosomal dihydrofolate reductase reveals natural antifolate resistance Acs Chem.Biol., 6, 2011
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4DPD
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![BU of 4dpd by Molmil](/molmil-images/mine/4dpd) | WILD TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PfDHFR-TS), DHF COMPLEX, NADP+, dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, DIHYDROFOLIC ACID, ... | 著者 | Yuthavong, Y, Vilaivan, T, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Chitnumsub, P, Tarnchompoo, B, Thongphanchang, C, Taweechai, S, Vanichtanakul, J, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-02-13 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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1PYB
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![BU of 1pyb by Molmil](/molmil-images/mine/1pyb) | Crystal Structure of Aquifex aeolicus Trbp111: a Structure-Specific tRNA Binding Protein | 分子名称: | tRNA-binding protein Trbp111 | 著者 | Swairjo, M.A, Morales, A.J, Wang, C.C, Ortiz, A.R, Schimmel, P. | 登録日 | 2003-07-08 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of trbp111: a structure-specific tRNA-binding protein. Embo J., 19, 2000
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4DDR
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![BU of 4ddr by Molmil](/molmil-images/mine/4ddr) | Human dihydrofolate reductase complexed with NADPH and P218 | 分子名称: | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Yuthavong, Y, Tarnchompoo, B, Vilaivan, T, Chitnumsub, P, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Thongphanchang, C, Taweechai, S, Vanichtanankul, J, Rattanajak, R, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-01-19 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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4CHV
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![BU of 4chv by Molmil](/molmil-images/mine/4chv) | The electron crystallography structure of the cAMP-bound potassium channel MloK1 | 分子名称: | CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION | 著者 | Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. | 登録日 | 2013-12-04 | 公開日 | 2014-01-15 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1 Nat.Commun., 5, 2014
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1Q7S
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![BU of 1q7s by Molmil](/molmil-images/mine/1q7s) | Crystal structure of bit1 | 分子名称: | bit1 | 著者 | De Pereda, J.M, Waas, W.F, Jan, Y, Ruoslahti, E, Schimmel, P, Pascual, J. | 登録日 | 2003-08-19 | 公開日 | 2003-12-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity. J.Biol.Chem., 279, 2004
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4DPH
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![BU of 4dph by Molmil](/molmil-images/mine/4dph) | Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with P65 and NADPH | 分子名称: | 2,4-diamino-6-methyl-5-[3-(2,4,5-trichlorophenoxy)propyloxy]pyrimidine, BETA-MERCAPTOETHANOL, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Yuthavong, Y, Vilaivan, T, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Chitnumsub, P, Tarnchompoo, B, Thongphanchang, C, Taweechai, S, Vanichtanakul, J, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-02-13 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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1RIQ
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![BU of 1riq by Molmil](/molmil-images/mine/1riq) | The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase | 分子名称: | Alanyl-tRNA synthetase | 著者 | Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | 登録日 | 2003-11-17 | 公開日 | 2004-04-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition Mol.Cell, 13, 2004
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4CHW
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![BU of 4chw by Molmil](/molmil-images/mine/4chw) | The electron crystallography structure of the cAMP-free potassium channel MloK1 | 分子名称: | CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION | 著者 | Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. | 登録日 | 2013-12-04 | 公開日 | 2014-01-15 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1. Nat Commun, 5, 2014
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4QC8
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![BU of 4qc8 by Molmil](/molmil-images/mine/4qc8) | Structural annotation of pathogenic bovine Parvovirus-1 | 分子名称: | VP2 | 著者 | Kailasan, S, Halder, S, Gurda, B.L, Bladek, H, Chipman, P.R, McKenna, R, Brown, K, Agbandje-McKenna, M. | 登録日 | 2014-05-09 | 公開日 | 2015-01-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of an enteric pathogen, bovine parvovirus. J.Virol., 89, 2015
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2X5I
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![BU of 2x5i by Molmil](/molmil-images/mine/2x5i) | Crystal structure echovirus 7 | 分子名称: | LAURIC ACID, VP1, VP2, ... | 著者 | Plevka, P, Hafenstein, S, Zhang, Y, Bowman, V.D, Chipman, P.R, Bator, C.M, Rossmann, M.G. | 登録日 | 2010-02-08 | 公開日 | 2010-12-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Interaction of Decay-Accelerating Factor with Echovirus 7. J.Virol., 84, 2010
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7L5W
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![BU of 7l5w by Molmil](/molmil-images/mine/7l5w) | p97-R155H mutant dodecamer I | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | 登録日 | 2020-12-23 | 公開日 | 2021-08-04 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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7L5X
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![BU of 7l5x by Molmil](/molmil-images/mine/7l5x) | p97-R155H mutant dodecamer II | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | 登録日 | 2020-12-23 | 公開日 | 2021-08-04 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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1UB5
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![BU of 1ub5 by Molmil](/molmil-images/mine/1ub5) | Crystal structure of Antibody 19G2 with hapten at 100K | 分子名称: | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, antibody 19G2, alpha chain, ... | 著者 | Beuscher, A.B, Wirsching, P, Lerner, R.A, Janda, K, Stevens, R.C. | 登録日 | 2003-03-30 | 公開日 | 2004-04-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures To be published
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4BPC
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2BYF
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![BU of 2byf by Molmil](/molmil-images/mine/2byf) | NMR solution structure of phospholipase c epsilon RA 2 domain | 分子名称: | PHOSPHOLIPASE C, EPSILON 1 | 著者 | Bunney, T.D, Harris, R, Gandarillas, N.L, Josephs, M.B, Roe, S.M, Paterson, H.F, Rodrigues-Lima, F, Esposito, D, Gieschik, P, Pearl, L.H, Driscoll, P.C, Katan, M. | 登録日 | 2005-08-01 | 公開日 | 2006-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon. Mol.Cell, 21, 2006
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2BYE
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![BU of 2bye by Molmil](/molmil-images/mine/2bye) | NMR solution structure of phospholipase c epsilon RA 1 domain | 分子名称: | PHOSPHOLIPASE C, EPSILON 1 | 著者 | Bunney, T.D, Harris, R, Gandarillas, N.L, Josephs, M.B, Roe, S.M, Paterson, H.F, Rodrigues-Lima, F, Esposito, D, Gieschik, P, Pearl, L.H, Driscoll, P.C, Katan, M. | 登録日 | 2005-08-01 | 公開日 | 2006-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon. Mol.Cell, 21, 2006
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2BL9
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![BU of 2bl9 by Molmil](/molmil-images/mine/2bl9) | X-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine and its derivative | 分子名称: | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kongsaeree, P, Khongsuk, P, Leartsakulpanich, U, Chitnumsub, P, Tarnchompoo, B, Walkinshaw, M.D, Yuthavong, Y. | 登録日 | 2005-03-02 | 公開日 | 2005-09-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Dihydrofolate Reductase from Plasmodium Vivax: Pyrimethamine Displacement Linked with Mutation-Induced Resistance. Proc.Natl.Acad.Sci.USA, 102, 2005
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