3T6N
 
 | |
2RFU
 | | Crystal structure of influenza B virus hemagglutinin in complex with LSTc receptor analog | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza B hemagglutinin (HA), ... | | 著者 | Wang, Q, Tian, X, Chen, X, Ma, J. | | 登録日 | 2007-10-01 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2RFT
 | | Crystal structure of influenza B virus hemagglutinin in complex with LSTa receptor analog | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza B hemagglutinin (HA), ... | | 著者 | Wang, Q, Tian, X, Chen, X, Ma, J. | | 登録日 | 2007-10-01 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
9JFF
 | | Crystal structure of L-threonine-O-3-phosphate decarboxylase CobC in complex with reaction intermediate | | 分子名称: | CHLORIDE ION, GLYCEROL, SODIUM ION, ... | | 著者 | Jiang, M, Guo, S, Chen, X, Wei, Q, Wang, M. | | 登録日 | 2024-09-04 | | 公開日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of l-threonine-O-3-phosphate decarboxylase CobC from Sinorhizobium meliloti involved in vitamin B 12 biosynthesis.
Biochem.Biophys.Res.Commun., 734, 2024
|
|
9JFB
 | | Crystal structure of L-threonine-O-3-phosphate decarboxylase CobC | | 分子名称: | CHLORIDE ION, GLYCEROL, SODIUM ION, ... | | 著者 | Jiang, M, Guo, S, Chen, X, Wei, Q, Wang, M. | | 登録日 | 2024-09-04 | | 公開日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of l-threonine-O-3-phosphate decarboxylase CobC from Sinorhizobium meliloti involved in vitamin B 12 biosynthesis.
Biochem.Biophys.Res.Commun., 734, 2024
|
|
3V6G
 | |
3V78
 | | Crystal Structure of Transcriptional Regulator | | 分子名称: | ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | | 著者 | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | | 登録日 | 2011-12-20 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis.
Nucleic Acids Res., 40, 2012
|
|
9IS7
 | | Paracandidimonas lactea CP group II intron 2S state | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, RNA (153-MER), ... | | 著者 | Wang, L, Xie, J.H, Zhang, C, Zou, J, Huang, Z, Shang, S, Chen, X, Yang, Y, Liu, J, Dong, H, Huang, D, Su, Z. | | 登録日 | 2024-07-17 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Structural basis of circularly permuted group II intron self-splicing.
Nat.Struct.Mol.Biol., 2025
|
|
9IJU
 | | Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region | | 分子名称: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Shi, L, Xu, Z, Chen, X, Xiong, B, Zhang, N. | | 登録日 | 2024-06-25 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.
J.Med.Chem., 68, 2025
|
|
9IML
 | | Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region | | 分子名称: | 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Shi, L, Xu, Z, Chen, X, Xiong, B, Zhang, N. | | 登録日 | 2024-07-03 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.
J.Med.Chem., 68, 2025
|
|
4IAN
 | | Crystal Structure of apo Human PRPF4B kinase domain | | 分子名称: | SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | | 著者 | Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. | | 登録日 | 2012-12-06 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
|
|
4IFC
 | | Crystal Structure of ADP-bound Human PRPF4B kinase domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | | 著者 | Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. | | 登録日 | 2012-12-14 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
|
|
4IJP
 | | Crystal Structure of Human PRPF4B kinase domain in complex with 4-{5-[(2-Chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thiophene-2-carboxylic acid amine | | 分子名称: | 4-(5-{[(2-chloropyridin-4-yl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | | 著者 | Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. | | 登録日 | 2012-12-22 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
|
|
4ICK
 | | Crystal structure of human AP4A hydrolase E58A mutant | | 分子名称: | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], GLYCEROL, MAGNESIUM ION, ... | | 著者 | Ge, H, Chen, X. | | 登録日 | 2012-12-10 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochem.Biophys.Res.Commun., 432, 2013
|
|
4IIR
 | | Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | 著者 | Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. | | 登録日 | 2012-12-20 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
|
|
4IJX
 | |
5H64
 | | Cryo-EM structure of mTORC1 | | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | | 登録日 | 2016-11-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
|
|
4KNB
 | | C-Met in complex with OSI ligand | | 分子名称: | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | | 著者 | Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J. | | 登録日 | 2013-05-09 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
|
|
5IHZ
 | | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain | | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | | 登録日 | 2016-03-01 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
|
|
5IG7
 | | Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPQQPFP | | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | | 登録日 | 2016-02-27 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
|
|
5IK3
 | | Crystal structure of anti-gliadin 1002-1E03 Fab fragment | | 分子名称: | 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION | | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | | 登録日 | 2016-03-03 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
|
|
5IJK
 | | Crystal structure of anti-gliadin 1002-1E03 Fab fragment in complex of peptide PLQPEQPFP | | 分子名称: | 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION, ... | | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | | 登録日 | 2016-03-02 | | 公開日 | 2017-03-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
|
|
5IFJ
 | | Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP | | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | | 登録日 | 2016-02-26 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
|
|
7CN9
 | | Cryo-EM structure of SARS-CoV-2 Spike ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | | 登録日 | 2020-07-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2.
Cell Rep, 32, 2020
|
|
4NKJ
 | |
