474D
 
 | | A NOVEL END-TO-END BINDING OF TWO NETROPSINS TO THE DNA DECAMER D(CCCCCIIIII)2 | | 分子名称: | DNA (5'-D(*CP*CP*CP*(CBR)P*CP*IP*IP*IP*IP*I)-3'), NETROPSIN | | 著者 | Chen, X, Rao, S.T, Sekar, K, Sundaralingam, M. | | 登録日 | 1998-01-14 | | 公開日 | 1998-12-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel end-to-end binding of two netropsins to the DNA decamers d(CCCCCIIIII)2, d(CCCBr5CCIIIII)2and d(CBr5CCCCIIIII)2.
Nucleic Acids Res., 26, 1998
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8YZ5
 | | SARS-CoV-2 Delta Spike in complex with Fab of JE-5C | | 分子名称: | Fab heavy chain of JE-5C, Fab light chain of JE-5C, Spike glycoprotein | | 著者 | Chen, X, Wu, Y.-M. | | 登録日 | 2024-04-06 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | | 主引用文献 | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine
Plos Pathog., 2024
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8YZ6
 | | SARS-CoV-2 Spike (BA.1) in complex with Fab of JH-8B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain of JH-8B, ... | | 著者 | Chen, X, Wu, Y.-M. | | 登録日 | 2024-04-06 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | | 主引用文献 | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine
Plos Pathog., 2024
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4JHD
 | | Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu | | 分子名称: | Actin-5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Chen, X, Ni, F, Wang, Q. | | 登録日 | 2013-03-04 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
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7XWW
 | | Crystal structure of NTR in complex with BN-XB | | 分子名称: | 2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-8-[1-[(4-nitrophenyl)methyl]pyridin-1-ium-4-yl]-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaene, Dihydropteridine reductase, FLAVIN MONONUCLEOTIDE | | 著者 | Chen, X, Chen, J, Li, J.L. | | 登録日 | 2022-05-27 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of NTR in complex with BN-XB
To Be Published
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4ZD3
 | | Structure of a transglutaminase 2-specific autoantibody Fab fragment | | 分子名称: | 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain | | 著者 | Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. | | 登録日 | 2015-04-16 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.
J.Biol.Chem., 290, 2015
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2KQZ
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2KR0
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2N3T
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2N3W
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2N3U
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2N3V
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8GI6
 | | Crystal structure of RhoA mutant L69R complexed with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | 著者 | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | | 登録日 | 2023-03-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Ras-like GTPases mutant structures
To be published
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8GI3
 | | Crystal structure of RhoA mutant L69P complexed with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | 著者 | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | | 登録日 | 2023-03-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Ras-like GTPases mutants structure
To be published
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6DUP
 | | CRYSTAL STRUCTURE OF PXR IN COMPLEX WITH COMPOUND 7 | | 分子名称: | (2S)-2-({[3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]oxy}methyl)-2,3-dihydro-7H-[1,3]oxazolo[3,2-a]pyrimidin-7-one, Nuclear receptor subfamily 1 group I member 2 | | 著者 | Chen, X, Zhang, Y, Mclean, L.R. | | 登録日 | 2018-06-21 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators.
Bioorg. Med. Chem. Lett., 28, 2018
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7X9E
 | | Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide | | 分子名称: | 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide | | 著者 | Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B. | | 登録日 | 2022-03-15 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.
Nat Microbiol, 7, 2022
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7F8L
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159D
 | | SIDE BY SIDE BINDING OF TWO DISTAMYCIN A DRUGS IN THE MINOR GROOVE OF AN ALTERNATING B-DNA DUPLEX | | 分子名称: | DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*CP*IP*CP*IP*C)-3'), MAGNESIUM ION | | 著者 | Chen, X, Ramakrishnan, B, Rao, S.T, Sundaralingam, M. | | 登録日 | 1994-02-10 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Binding of two distamycin A molecules in the minor groove of an alternating B-DNA duplex.
Nat.Struct.Biol., 1, 1994
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5IRS
 | | crystal structure of the proteasomal Rpn13 PRU-domain | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Proteasomal ubiquitin receptor ADRM1 | | 著者 | Chen, X, Shi, K, Walters, K, Aihara, H. | | 登録日 | 2016-03-14 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
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3DR9
 | | Increased Distal Histidine Conformational Flexibility in the Deoxy Form of Dehaloperoxidase from Amphitrite ornata | | 分子名称: | Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Chen, X, de Serrano, V.S, Betts, L, Franzen, S. | | 登録日 | 2008-07-10 | | 公開日 | 2009-01-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata.
Acta Crystallogr.,Sect.D, 65, 2009
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7XUP
 | | Crystal structure of TPe3.0 | | 分子名称: | Transcriptional regulator, PadR-like family | | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | | 登録日 | 2022-05-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes.
Nature, 611, 2022
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7XUQ
 | | Crystal structure of Tpe3.0 complexed with N-Boc-3-alkenylindole | | 分子名称: | Transcriptional regulator, PadR-like family, dimethyl 2-[[2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]methyl]-2-prop-2-enyl-propanedioate | | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | | 登録日 | 2022-05-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes.
Nature, 611, 2022
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7CK9
 | | Crystal structure of Doxorubicin loaded human ferritin heavy chain | | 分子名称: | CHLORIDE ION, Ferritin heavy chain, GLYCEROL, ... | | 著者 | Chen, X, Jiang, B, Yan, X, Fan, K. | | 登録日 | 2020-07-16 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | | 主引用文献 | A natural drug entry channel in the ferritin nanocage.
Nano Today, 35, 2020
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7CK8
 | | Crystal structure of human ferritin heavy chain mutant C90S/C102S/C130S | | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ... | | 著者 | Chen, X, Jiang, B, Yan, X, Fan, K. | | 登録日 | 2020-07-16 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A natural drug entry channel in the ferritin nanocage.
Nano Today, 35, 2020
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7F4G
 | | Structure of RPAP2-bound RNA polymerase II | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. | | 登録日 | 2021-06-18 | | 公開日 | 2021-07-07 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
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