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PDB: 713 件
2Z8N
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Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: 27.5 kDa virulence protein, SULFATE ION
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
1PSA
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BU of 1psa by Molmil
STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR
分子名称: N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide, PEPSIN A
著者Chen, L, Abad-Zapatero, C.
登録日1991-10-22
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor.
Acta Crystallogr.,Sect.B, 48, 1992
7YNK
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Structure of human SGLT2-MAP17 complex in the apo state in the inward-facing conformation
分子名称: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2
著者Chen, L, Niu, Y.
登録日2022-07-31
公開日2023-05-31
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNJ
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Structure of human SGLT2-MAP17 complex bound with substrate AMG in the occluded conformation
分子名称: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2, methyl alpha-D-glucopyranoside
著者Chen, L, Niu, Y, Cui, W.
登録日2022-07-31
公開日2023-05-31
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNI
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BU of 7yni by Molmil
Structure of human SGLT1-MAP17 complex bound with substrate 4D4FDG in the occluded conformation
分子名称: (2R,3R,4R,5S,6R)-5-fluoranyl-6-(hydroxymethyl)oxane-2,3,4-triol, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1
著者Chen, L, Niu, Y, Cui, W.
登録日2022-07-31
公開日2023-05-31
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
2Z8P
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BU of 2z8p by Molmil
Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: (GLY)(GLU)(ALA)(TPO)(VAL)(PTR)(ALA), 27.5 kDa virulence protein
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
5TIH
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BU of 5tih by Molmil
Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
分子名称: ACETATE ION, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ...
著者Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
2Z8M
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BU of 2z8m by Molmil
Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: 27.5 kDa virulence protein
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
4U1Z
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GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form D
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9401 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U21
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GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3908 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U5G
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BU of 4u5g by Molmil
Crystal structure of con-ikot-ikot toxin
分子名称: Con-ikot-ikot, ZINC ION
著者Chen, L, Gouaux, E.
登録日2014-07-25
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1997 Å)
主引用文献X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U22
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BU of 4u22 by Molmil
GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4409 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U23
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BU of 4u23 by Molmil
GluA2flip sLBD complexed with FW and (R,R)-2b crystal form F
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6734 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
2DFL
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BU of 2dfl by Molmil
Crystal structure of left-handed RadA filament
分子名称: DNA repair and recombination protein radA
著者Chen, L.T, Ko, T.P, Wang, T.F, Wang, A.H.J.
登録日2006-03-02
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins
Nucleic Acids Res., 35, 2007
4U1O
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BU of 4u1o by Molmil
GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form C
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-15
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8501 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
1WMS
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BU of 1wms by Molmil
High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target
分子名称: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-9A
著者Chen, L, DiGiammarino, E, Zhou, X.E, Wang, Y, Toh, D, Hodge, T.W, Meehan, E.J.
登録日2004-07-16
公開日2004-09-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
7VLT
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BU of 7vlt by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP and levcromakalim
分子名称: (3S,4R)-2,2-dimethyl-3-oxidanyl-4-(2-oxidanylidenepyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLR
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BU of 7vlr by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLU
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BU of 7vlu by Molmil
Structure of SUR2A in complex with Mg-ATP/ADP and P1075
分子名称: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLS
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BU of 7vls by Molmil
Structure of SUR2B in complex with MgATP/ADP and P1075
分子名称: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
3WL0
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Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain E148A mutant in complex with a(GlcNAc)2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
3WKZ
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Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
1ZLM
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BU of 1zlm by Molmil
Crystal structure of the SH3 domain of human osteoclast stimulating factor
分子名称: Osteoclast stimulating factor 1
著者Chen, L, Wang, Y, Wells, D, Toh, D, Harold, H, Zhou, J, DiGiammarino, E, Meehan, E.J.
登録日2005-05-06
公開日2006-05-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Structure of the SH3 domain of human osteoclast-stimulating factor at atomic resolution.
Acta Crystallogr.,Sect.F, 62, 2006
3WL1
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BU of 3wl1 by Molmil
Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain in complex with reaction products (GlcNAc)2,3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q.
登録日2013-11-05
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.
Acta Crystallogr.,Sect.D, 70, 2014
1DKD
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CRYSTAL STRUCTURE OF A GROEL (APICAL DOMAIN) AND A DODECAMERIC PEPTIDE COMPLEX
分子名称: 12-MER PEPTIDE, GROEL
著者Chen, L, Sigler, P.B.
登録日1999-12-07
公開日2000-01-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity.
Cell(Cambridge,Mass.), 99, 1999

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