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PDB: 748 件

2O94
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The 97H/F mutant Structure of a glutamine-rich domain from histone deacetylase 4
分子名称: Histone deacetylase 4
著者Guo, L, Han, A, Bates, D.L, Chen, L.
登録日2006-12-13
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3WZF
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Crystal structure of human cytoplasmic aspartate aminotransferase
分子名称: Aspartate aminotransferase, cytoplasmic
著者Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q.
登録日2014-09-24
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
2P9J
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Crystal structure of AQ2171 from Aquifex aeolicus
分子名称: Hypothetical protein AQ2171
著者Yang, H, Chen, L, Agari, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-26
公開日2007-05-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of AQ2171 from Aquifex aeolicus
To be Published
2P2O
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Crystal structure of maltose transacetylase from Geobacillus kaustophilus P2(1) crystal form
分子名称: Maltose transacetylase
著者Liu, Z.J, Li, Y, Chen, L, Zhu, J, Rose, J.P, Ebihara, A, Yokoyama, S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-07
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal Structure of Maltose Transacetylase from Geobacillus Kaustophilus at 1.8 Angstrom Resolution
To be Published
1OWR
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CRYSTAL STRUCTURE OF HUMAN NFAT1 BOUND MONOMERICALLY TO DNA
分子名称: NFAT1 Monomeric Binding Site, Minus Strand, Plus Strand, ...
著者Stroud, J.C, Chen, L.
登録日2003-03-29
公開日2004-02-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of NFAT Bound to DNA as a Monomer
J.Mol.Biol., 334, 2003
2AHY
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Na+ complex of the NaK Channel
分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION
著者Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y.
登録日2005-07-28
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic structure of a Na+- and K+-conducting channel.
Nature, 440, 2006
2P5U
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Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
著者Fu, Z.-Q, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Dillard, B, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-16
公開日2007-04-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published
2AHZ
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K+ complex of the NaK Channel
分子名称: CALCIUM ION, POTASSIUM ION, Potassium channel protein
著者Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y.
登録日2005-07-28
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure of a Na+- and K+-conducting channel.
Nature, 440, 2006
1ZTD
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Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
分子名称: Hypothetical Protein Pfu-631545-001
著者Fu, Z.-Q, Horanyi, P, Florence, Q, Liu, Z.-J, Chen, L, Lee, D, Habel, J, Xu, H, Nguyen, D, Chang, S.-H, Zhou, W, Zhang, H, Jenney Jr, F.E, Sha, B, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-05-26
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
To be Published
3CQ2
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Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein (other form) from Thermus Thermophilus HB8
分子名称: Putative uncharacterized protein TTHB138
著者Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Satoh, S, Kitamura, Y, Ebihara, A, Chen, L, Liu, Z.J, Wang, B.C, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-02
公開日2009-04-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein from Thermus Thermophilus HB8
To be Published
7ULQ
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Recombinant Hannalgesin
分子名称: ACETATE ION, GLYCEROL, Long neurotoxin OH-55, ...
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of recombinant Hannalgesin at 2.2 Angstroms resolution.
To Be Published
2AEF
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Crystal Structures of the MthK RCK Domain in Ca2+ bound form
分子名称: CALCIUM ION, Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
2CW9
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Crystal structure of human Tim44 C-terminal domain
分子名称: PENTAETHYLENE GLYCOL, translocase of inner mitochondrial membrane
著者Handa, N, Kishishita, S, Morita, S, Kinoshita, Y, Nagano, Y, Uda, H, Terada, T, Uchikubo, T, Takemoto, C, Jin, Z, Chrzas, J, Chen, L, Liu, Z.-J, Wang, B.-C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-17
公開日2005-12-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the human Tim44 C-terminal domain in complex with pentaethylene glycol: ligand-bound form.
Acta Crystallogr.,Sect.D, 63, 2007
3B9M
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Human serum albumin complexed with myristate, 3'-azido-3'-deoxythymidine (AZT) and salicylic acid
分子名称: 2-HYDROXYBENZOIC ACID, 3'-azido-3'-deoxythymidine, MYRISTIC ACID, ...
著者Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
登録日2007-11-05
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
2P3E
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Crystal structure of AQ1208 from Aquifex aeolicus
分子名称: Diaminopimelate decarboxylase
著者Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-08
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献To be Published
To be Published
3B9L
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Human serum albumin complexed with myristate and AZT
分子名称: 3'-azido-3'-deoxythymidine, MYRISTIC ACID, Serum albumin
著者Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
登録日2007-11-05
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
8B9P
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ACE2 in complex with bicyclic peptide inhibitor
分子名称: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-GLY-ARG-GLN-PHE-CYS-HIS-THR-LEU-MET-PRO-ARG-HIS-LEU-CYS-ALA-NH2, Processed angiotensin-converting enzyme 2
著者Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
登録日2022-10-06
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
8BFW
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The structures of Ace2 in complex with bicyclic peptide inhibitor
分子名称: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-VAL-ARG-SER-HIS-CYS-SER-SER-LEU-LEU-PRO-ARG-ILE-HIS-CYS-ALA-NH2, Processed angiotensin-converting enzyme 2
著者Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
登録日2022-10-27
公開日2023-10-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
4U2Q
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Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2
著者Duerr, K.L, Chen, L, Gouaux, E.
登録日2014-07-17
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.5247 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U2R
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Crystal structure of the GLUR2 ligand binding core (S1S2J, flip variant) in the apo state
分子名称: Glutamate receptor 2, SULFATE ION
著者Duerr, K.L, Chen, L, Gouaux, E.
登録日2014-07-17
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4114 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4R4Z
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Structure of PNGF-II in P21 space group
分子名称: PNGF-II
著者Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L.
登録日2014-08-20
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Identification and Characterization of a Novel Prokaryotic Peptide: N-glycosidase from Elizabethkingia meningoseptica
J.Biol.Chem., 2015
4R4X
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Structure of PNGF-II in C2 space group
分子名称: PNGF-II, ZINC ION
著者Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L.
登録日2014-08-20
公開日2015-01-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification and Characterization of a Novel Prokaryotic Peptide: N-glycosidase from Elizabethkingia meningoseptica
J.Biol.Chem., 2015
3DAE
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Crystal structure of phosphorylated SNF1 kinase domain
分子名称: Carbon catabolite-derepressing protein kinase
著者Zheng, L.-S, Chen, L, Jiao, Z.-H, Wu, J.-W.
登録日2008-05-29
公開日2009-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
Nature, 459, 2009
3ELO
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Crystal Structure of Human Pancreatic Prophospholipase A2
分子名称: Phospholipase A2, SULFATE ION
著者Xu, W, Yi, L, Feng, Y, Chen, L, Liu, J.
登録日2008-09-22
公開日2009-04-14
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insight into the activation mechanism of human pancreatic prophospholipase A2
J.Biol.Chem., 284, 2009
6U6V
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Crystal structure of human PD-1H / VISTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation
著者Slater, B.T, Han, X, Chen, L, Xiong, Y.
登録日2019-08-30
公開日2020-01-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into T cell coinhibition by PD-1H (VISTA).
Proc.Natl.Acad.Sci.USA, 117, 2020

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