PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Selective pharmacological inhibition of the CREB binding protein bromodomain regulates inflammatory cytokines in macrophages and RGS4 in neurons
Descriptor:	5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]-1-[2-(morpholin-4-yl)ethyl]-1H-benzimidazole, CREB-binding protein
Authors:	Chekler, E.L, Jones, L.H.
Deposit date:	2015-07-09
Release date:	2016-04-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.96 Å)
Cite:	Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities. Chem.Biol., 22, 2015

Selective pharmacological inhibition of the CREB binding protein bromodomain regulates inflammatory cytokines in macrophages and RGS4 in neurons
Descriptor:	5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]-1-[2-(morpholin-4-yl)ethyl]-1H-benzimidazole, Bromodomain-containing protein 4
Authors:	Chekler, E.L, Jones, L.H.
Deposit date:	2015-07-08
Release date:	2016-04-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.15 Å)
Cite:	Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities. Chem.Biol., 22, 2015

Direct photocapture of bromodomains using tropolone chemical probes
Descriptor:	1,2-ETHANEDIOL, 2-methoxy-4-{1-[2-(morpholin-4-yl)ethyl]-2-(2-phenylethyl)-1H-benzimidazol-5-yl}cyclohepta-2,4,6-trien-1-one, Bromodomain-containing protein 4
Authors:	Hett, E.C, Piatnitski Chekler, E.L, Basak, A, Bonin, P.D, Denny, R.A, Flick, A.C, Geoghegan, K.F, Liu, S, Pletcher, M.T, Robinson, R.P, Sahasrabudhe, P, Salter, S, Stock, I.A, Jones, L.H.
Deposit date:	2014-09-23
Release date:	2015-10-28
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.345 Å)
Cite:	Direct photocapture of bromodomains using tropolone chemical probes To Be Published