3OEU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oeu by Molmil](/molmil-images/mine/3oeu) | Structure of yeast 20S open-gate proteasome with Compound 24 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-{(2S)-1-[(2-chlorobenzyl)amino]-1-oxo-4-phenylbutan-2-yl}-N~2~-[3-(2-methylphenyl)propanoyl]-L-threoninamide, ... | 著者 | Sintchak, M.D. | 登録日 | 2010-08-13 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1A7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a7y by Molmil](/molmil-images/mine/1a7y) | CRYSTAL STRUCTURE OF ACTINOMYCIN D | 分子名称: | ACTINOMYCIN D, ETHYL ACETATE, METHANOL | 著者 | Schafer, M, Sheldrick, G.M, Bahner, I, Lackner, H. | 登録日 | 1998-03-19 | 公開日 | 1999-03-23 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (0.94 Å) | 主引用文献 | Crystal Structures of Actinomycin D and Actinomycin Z3. Angew.Chem.Int.Ed.Engl., 37, 1998
|
|
4MCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mck by Molmil](/molmil-images/mine/4mck) | |
3THB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3thb by Molmil](/molmil-images/mine/3thb) | Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor | 分子名称: | 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thi one, Serine/threonine-protein kinase PLK1, ZINC ION | 著者 | Sintchak, M.D. | 登録日 | 2011-08-18 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J.Med.Chem., 55, 2012
|
|
1ZNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1znt by Molmil](/molmil-images/mine/1znt) | 18 NMR structures of AcAMP2-Like Peptide with non Natural Fluoroaromatic Residue (AcAMP2F18Pff/Y20Pff) complex with N,N,N-triacetylchitotriose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMARANTHUS CAUDATUS ANTIMICROBIAL PEPTIDE 2 | 著者 | Chavez, M.I, Andreu, C, Vidal, P, Aboitiz, N, Freire, F, Groves, P, Asensio, J.L, Asensio, G, Muraki, M, Canada, F.J, Jimenez-Barbero, J. | 登録日 | 2005-05-12 | 公開日 | 2005-12-06 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | On the Importance of Carbohydrate-Aromatic Interactions for the Molecular Recognition of Oligosaccharides by Proteins: NMR Studies of the Structure and Binding Affinity of AcAMP2-like Peptides with Non-Natural Naphthyl and Fluoroaromatic Residues Chemistry, 11, 2005
|
|
3OEV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oev by Molmil](/molmil-images/mine/3oev) | Structure of yeast 20S open-gate proteasome with Compound 25 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(benzyloxy)-N-[(2S,3R)-3-hydroxy-1-{[(2S)-1-{[(3-methylthiophen-2-yl)methyl]amino}-1-oxo-4-phenylbutan-2-yl]amino}-1-oxobutan-2-yl]benzamide, MAGNESIUM ION, ... | 著者 | Sintchak, M.D. | 登録日 | 2010-08-13 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1AOR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1aor by Molmil](/molmil-images/mine/1aor) | STRUCTURE OF A HYPERTHERMOPHILIC TUNGSTOPTERIN ENZYME, ALDEHYDE FERREDOXIN OXIDOREDUCTASE | 分子名称: | ALDEHYDE FERREDOXIN OXIDOREDUCTASE, FE (III) ION, IRON/SULFUR CLUSTER, ... | 著者 | Chan, M.K, Mukund, S, Kletzin, A, Adams, M.W.W, Rees, D.C. | 登録日 | 1995-02-13 | 公開日 | 1995-04-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase. Science, 267, 1995
|
|
1A7Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a7z by Molmil](/molmil-images/mine/1a7z) | CRYSTAL STRUCTURE OF ACTINOMYCIN Z3 | 分子名称: | ACTINOMYCIN Z3, BENZENE | 著者 | Schafer, M. | 登録日 | 1998-03-19 | 公開日 | 1999-03-23 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Crystal Structures of Actinomycin D and Actinomycin Z3. Angew.Chem.Int.Ed.Engl., 37, 1998
|
|
2WQM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wqm by Molmil](/molmil-images/mine/2wqm) | Structure of apo human Nek7 | 分子名称: | NICKEL (II) ION, SERINE/THREONINE-PROTEIN KINASE NEK7, SULFATE ION | 著者 | Richards, M.W, Bayliss, R. | 登録日 | 2009-08-24 | 公開日 | 2009-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An Auto-Inhibitory Tyrosine Motif in the Cell-Cycle Regulated Nek7 Kinase is Released Through Binding of Nek9 Mol.Cell, 36, 2009
|
|
4NET
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4net by Molmil](/molmil-images/mine/4net) | Crystal structure of ADC-1 beta-lactamase | 分子名称: | AmpC, GLYCEROL, NITRATE ION | 著者 | Bhattacharya, M, Toth, M, Antunes, N.T, Smith, C.A, Vakulenko, S.B. | 登録日 | 2013-10-30 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure of the extended-spectrum class C beta-lactamase ADC-1 from Acinetobacter baumannii. Acta Crystallogr.,Sect.D, 70, 2014
|
|
3SDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdi by Molmil](/molmil-images/mine/3sdi) | Structure of yeast 20S open-gate proteasome with Compound 20 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N~4~-(2,2-dimethylpropyl)-N~1~-{(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}-N~2~-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-aspartamide, ... | 著者 | Sintchak, M.D. | 登録日 | 2011-06-09 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
|
|
2WT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wt8 by Molmil](/molmil-images/mine/2wt8) | |
3SDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdk by Molmil](/molmil-images/mine/3sdk) | Structure of yeast 20S open-gate proteasome with Compound 34 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(2S)-3-(3-tert-butyl-1,2,4-oxadiazol-5-yl)-1-({(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}amino)-1-oxopropan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide, ... | 著者 | Sintchak, M.D. | 登録日 | 2011-06-09 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
|
|
3SQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sqb by Molmil](/molmil-images/mine/3sqb) | Structure of the major type 1 pilus subunit FimA bound to the FimC chaperone | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chaperone protein fimC, ... | 著者 | Scharer, M.A, Eidam, O, Grutter, M.G, Glockshuber, R, Capitani, G. | 登録日 | 2011-07-05 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Quality control of disulfide bond formation in pilus subunits by the chaperone FimC. Nat.Chem.Biol., 8, 2012
|
|
1R09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r09 by Molmil](/molmil-images/mine/1r09) | HUMAN RHINOVIRUS 14 COMPLEXED WITH ANTIVIRAL COMPOUND R 61837 | 分子名称: | 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE, DIMETHYL SULFOXIDE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), ... | 著者 | Chapman, M.S, Minor, I, Rossmann, M.G, Diana, G.D, Andries, K. | 登録日 | 1990-05-04 | 公開日 | 1991-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Human rhinovirus 14 complexed with antiviral compound R 61837. J.Mol.Biol., 217, 1991
|
|
2WQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wqn by Molmil](/molmil-images/mine/2wqn) | Structure of ADP-bound human Nek7 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICKEL (II) ION, ... | 著者 | Richards, M.W, Bayliss, R. | 登録日 | 2009-08-24 | 公開日 | 2009-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9. Mol.Cell, 36, 2009
|
|
4G4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g4g by Molmil](/molmil-images/mine/4g4g) | Crystal structure of recombinant glucuronoyl esterase from Sporotrichum thermophile determined at 1.55 A resolution | 分子名称: | 1,2-ETHANEDIOL, 4-O-methyl-glucuronoyl methylesterase, GLYCEROL | 著者 | Charavgi, M.D, Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | 登録日 | 2012-07-16 | 公開日 | 2013-01-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst. Acta Crystallogr.,Sect.D, 69, 2013
|
|
2BHH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bhh by Molmil](/molmil-images/mine/2bhh) | HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE | 分子名称: | (2E,3S)-3-HYDROXY-5'-[(4-HYDROXYPIPERIDIN-1-YL)SULFONYL]-3-METHYL-1,3-DIHYDRO-2,3'-BIINDOL-2'(1'H)-ONE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Schaefer, M, Jautelat, R, Brumby, T, Briem, H, Eisenbrand, G, Schwahn, S, Krueger, M, Luecking, U, Prien, O, Siemeister, G. | 登録日 | 2005-01-11 | 公開日 | 2005-03-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | From the Insoluble Dye Indirubin Towards Highly Active, Soluble Cdk2-Inhibitors Chembiochem, 6, 2005
|
|
4G4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g4j by Molmil](/molmil-images/mine/4g4j) | Crystal structure of glucuronoyl esterase S213A mutant from Sporotrichum thermophile in complex with methyl 4-O-methyl-beta-D-glucopyranuronate determined at 2.35 A resolution | 分子名称: | 1,2-ETHANEDIOL, 4-O-methyl-glucuronoyl methylesterase, GLYCEROL, ... | 著者 | Charavgi, M.D, Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | 登録日 | 2012-07-16 | 公開日 | 2013-01-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst. Acta Crystallogr.,Sect.D, 69, 2013
|
|
2BHE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bhe by Molmil](/molmil-images/mine/2bhe) | HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 5-BROMO-INDIRUBINE | 分子名称: | (2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Schaefer, M, Jautelat, R, Brumby, T, Briem, H, Eisenbrand, G, Schwahn, S, Krueger, M, Luecking, U, Prien, O, Siemeister, G. | 登録日 | 2005-01-10 | 公開日 | 2005-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | From the Insoluble Dye Indirubin Towards Highly Active, Soluble Cdk2-Inhibitors Chembiochem, 6, 2005
|
|
4HUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hua by Molmil](/molmil-images/mine/4hua) | E. coli thioredoxin variant with (4R)-FluoroPro76 as single proline residue | 分子名称: | COPPER (II) ION, Thioredoxin-1 | 著者 | Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R. | 登録日 | 2012-11-02 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering. Chembiochem, 14, 2013
|
|
4HU9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hu9 by Molmil](/molmil-images/mine/4hu9) | E. coli thioredoxin variant with (4S)-FluoroPro76 as single proline residue | 分子名称: | COPPER (II) ION, Thioredoxin-1 | 著者 | Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R. | 登録日 | 2012-11-02 | 公開日 | 2013-05-29 | 最終更新日 | 2017-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering. Chembiochem, 14, 2013
|
|
2LRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lrd by Molmil](/molmil-images/mine/2lrd) | The solution structure of the monomeric Acanthaporin | 分子名称: | Acanthaporin | 著者 | Michalek, M, Soennichsen, F.D, Wechselberger, R, Dingley, A.J, Wienk, H, Simanski, M, Herbst, R, Lorenzen, I, Marciano-Cabral, F, Gelhaus, C, Groetzinger, J, Leippe, M. | 登録日 | 2012-03-28 | 公開日 | 2012-05-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba. Nat.Chem.Biol., 9, 2013
|
|
2J9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j9m by Molmil](/molmil-images/mine/2j9m) | Crystal Structure of CDK2 in complex with Macrocyclic Aminopyrimidine | 分子名称: | 6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Schaefer, M, Luecking, U, Siemeister, G, Briem, H, Krueger, M, Lienau, P, Jautelat, R. | 登録日 | 2006-11-13 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Macrocyclic Aminopyrimidines as Multitarget Cdk and Vegf-R Inhibitors with Potent Antiproliferative Activities. Chemmedchem, 2, 2007
|
|
2LRE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lre by Molmil](/molmil-images/mine/2lre) | The solution structure of the dimeric Acanthaporin | 分子名称: | Acanthaporin | 著者 | Michalek, M, Soennichsen, F.D, Wechselberger, R, Dingley, A.J, Wienk, H, Simanski, M, Herbst, R, Lorenzen, I, Marciano-Cabral, F, Gelhaus, C, Groetzinger, J, Leippe, M. | 登録日 | 2012-03-28 | 公開日 | 2012-05-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba. Nat.Chem.Biol., 9, 2013
|
|