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PDB: 10 results

3SL2
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ATP Forms a Stable Complex with the Essential Histidine Kinase WalK (YycG) Domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sensor histidine kinase yycG
Authors:Celikel, R, Veldore, V.H, Mathews, I, Devine, K, Varughese, K.I.
Deposit date:2011-06-23
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:ATP forms a stable complex with the essential histidine kinase WalK (YycG) domain.
Acta Crystallogr.,Sect.D, 68, 2012
1OAK
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CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR (VWF) A1 DOMAIN IN COMPLEX WITH THE FUNCTION BLOCKING NMC-4 FAB
Descriptor: NMC-4 IGG1, VON WILLEBRAND FACTOR
Authors:Celikel, R, Varughese, K.I.
Deposit date:1997-12-18
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab.
Nat.Struct.Biol., 5, 1998
4LAQ
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Crystal structure of a therapeutic single chain antibody in the free form
Descriptor: D-MALATE, NICKEL (II) ION, SULFATE ION, ...
Authors:Celikel, R, Gokulan, K, Peterson, E.C, Varughese, K.I.
Deposit date:2013-06-20
Release date:2014-01-08
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites.
Plos One, 8, 2013
3GM0
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Anti-methamphetamine single chain Fv in complex with MDMA
Descriptor: (2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine, anti-methamphetamine single chain Fv
Authors:Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I.
Deposit date:2009-03-12
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
3GKZ
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Crystal structures of a therapeutic single chain antibody in complex methamphetamine
Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, anti-methamphetamine single chain Fv
Authors:Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I.
Deposit date:2009-03-11
Release date:2009-10-06
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
3PMH
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Mechanism of Sulfotyrosine-Mediated Glycoprotein Ib Interaction with Two Distinct alpha-Thrombin Sites
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, Platelet glycoprotein Ib alpha chain, ...
Authors:Varughese, K.I, Celikel, R.
Deposit date:2010-11-16
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Proc.Natl.Acad.Sci.USA, 108, 2011
1FVU
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CRYSTAL STRUCTURE OF BOTROCETIN
Descriptor: BOTROCETIN ALPHA CHAIN, BOTROCETIN BETA CHAIN, MAGNESIUM ION
Authors:Sen, U, Vasudevan, S, Subbarao, G, McClintoc, R.A, Celikel, R, Ruggeri, Z.M, Varughese, K.I.
Deposit date:2000-09-20
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the von Willebrand factor modulator botrocetin.
Biochemistry, 40, 2001
1OOK
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Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ...
Authors:Varughese, K.I, Celikel, R, Ruggeri, Z.M.
Deposit date:2003-03-03
Release date:2003-07-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1P9A
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Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution
Descriptor: Platelet glycoprotein Ib alpha chain precursor, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Varughese, K.I, Celikel, R, Ruggeri, Z.M.
Deposit date:2003-05-09
Release date:2003-07-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1QYY
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Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Platelet glycoprotein Ib alpha chain, ...
Authors:Varughese, K.I, Ruggeri, Z.M, Celikel, R.
Deposit date:2003-09-12
Release date:2004-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Acta Crystallogr.,Sect.D, 60, 2004

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