8V3B
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7R2M
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![BU of 7r2m by Molmil](/molmil-images/mine/7r2m) | SYNJ2BP complex with a synthetic Vangl2 peptide (9mer). | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, GLYCEROL, ... | 著者 | Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. | 登録日 | 2022-02-04 | 公開日 | 2023-05-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
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7R2T
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![BU of 7r2t by Molmil](/molmil-images/mine/7r2t) | SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position. | 分子名称: | CALCIUM ION, GLYCEROL, Synaptojanin-2-binding protein,Annexin, ... | 著者 | Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. | 登録日 | 2022-02-05 | 公開日 | 2023-05-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
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8AEL
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![BU of 8ael by Molmil](/molmil-images/mine/8ael) | SYNJ2BP complex with a synthetic Vangl2 peptide (3mer). | 分子名称: | CALCIUM ION, GLY-GLY-GLY-THR-SER-VAL, GLYCEROL, ... | 著者 | Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. | 登録日 | 2022-07-13 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
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7Q3F
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![BU of 7q3f by Molmil](/molmil-images/mine/7q3f) | Bromodomain-containing 4 BD1 in complex with the inhibitor CRCM5484 | 分子名称: | 2-[[11-ethanoyl-4-(furan-2-ylmethyl)-3-oxidanylidene-8-thia-4,6,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-5-yl]sulfanyl]-~{N}-(2-methylpyridin-3-yl)ethanamide, Bromodomain-containing protein 4 | 著者 | Carrasco, K, Betzi, S, Morelli, X. | 登録日 | 2021-10-27 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation J.Med.Chem., 65, 2022
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7Q5O
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![BU of 7q5o by Molmil](/molmil-images/mine/7q5o) | Bromodomain-containing 2 BD2 in complex with the inhibitor CRCM5484 | 分子名称: | 1,2-ETHANEDIOL, 2-[[11-ethanoyl-4-(furan-2-ylmethyl)-3-oxidanylidene-8-thia-4,6,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-5-yl]sulfanyl]-~{N}-(2-methylpyridin-3-yl)ethanamide, Bromodomain-containing protein 2 | 著者 | Carrasco, K, Betzi, S, Morelli, X. | 登録日 | 2021-11-04 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.519 Å) | 主引用文献 | CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation J.Med.Chem., 65, 2022
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8B98
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8B96
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2QVF
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![BU of 2qvf by Molmil](/molmil-images/mine/2qvf) | mouse E-cadherin domains 1,2 | 分子名称: | CALCIUM ION, Epithelial-cadherin (E-cadherin) (Uvomorulin) (Cadherin-1) (ARC-1) (CD324 antigen) | 著者 | Carroll, K.J. | 登録日 | 2007-08-08 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | E-cadherin domains 1,2 To be Published
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7BO7
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![BU of 7bo7 by Molmil](/molmil-images/mine/7bo7) | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Brown, D, Robinson, C, Carr, K.H, Pande, V. | 登録日 | 2021-01-24 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 To Be Published
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5M53
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![BU of 5m53 by Molmil](/molmil-images/mine/5m53) | Nek2 bound to arylaminopurine inhibitor 11 | 分子名称: | 1,2-ETHANEDIOL, 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N},~{N}-dimethyl-benzamide, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bayliss, R, Carr, K.H. | 登録日 | 2016-10-20 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-guided design of purine-based probes for selective Nek2 inhibition. Oncotarget, 8, 2017
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8B9V
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![BU of 8b9v by Molmil](/molmil-images/mine/8b9v) | Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120 | 分子名称: | Alpha-synuclein 110-120, Lu AF82422 Fab heavy chain, Lu AF82422 Fab light chain, ... | 著者 | Bjerregaard-Andersen, K, Carr, K, Krogh, B.O, Kallunki, P, Tagmose, L, David, L. | 登録日 | 2022-10-10 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120 To Be Published
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3REZ
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![BU of 3rez by Molmil](/molmil-images/mine/3rez) | glycoprotein GPIb variant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Platelet glycoprotein Ib beta chain, ... | 著者 | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | 登録日 | 2011-04-05 | 公開日 | 2012-02-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIb beta and a GPIb beta/GPIX chimera Blood, 118, 2011
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3RFE
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![BU of 3rfe by Molmil](/molmil-images/mine/3rfe) | Crystal structure of glycoprotein GPIb ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Platelet glycoprotein Ib beta chain, ... | 著者 | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | 登録日 | 2011-04-06 | 公開日 | 2011-12-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.245 Å) | 主引用文献 | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbbeta and a GPIbbeta/GPIX chimer Blood, 118, 2011
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1S1G
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![BU of 1s1g by Molmil](/molmil-images/mine/1s1g) | Crystal Structure of Kv4.3 T1 Domain | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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1S1E
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![BU of 1s1e by Molmil](/molmil-images/mine/1s1e) | Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1) | 分子名称: | CALCIUM ION, Kv channel interacting protein 1 | 著者 | Scannevin, R.H, Wang, K.-W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.-X, Xu, Z.-B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2005-01-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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1S31
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![BU of 1s31 by Molmil](/molmil-images/mine/1s31) | Crystal Structure Analysis of the human Tub protein (isoform a) spanning residues 289 through 561 | 分子名称: | TRIETHYLENE GLYCOL, tubby isoform a | 著者 | Boutboul, S, Carroll, K.J, Basdevant, A, Gomez, C, Nandrot, E, Clement, K, Shapiro, L, Abitbol, M. | 登録日 | 2004-01-12 | 公開日 | 2005-01-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | A novel human obesity and sensory deficit syndrome resulting from a mutation in the TUB gene To be Published
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3ZJE
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![BU of 3zje by Molmil](/molmil-images/mine/3zje) | A20 OTU domain in reversibly oxidised (SOH) state | 分子名称: | 1,2-ETHANEDIOL, A20P50, CHLORIDE ION | 著者 | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | 登録日 | 2013-01-17 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation Nat.Commun., 4, 2013
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3ZJG
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![BU of 3zjg by Molmil](/molmil-images/mine/3zjg) | A20 OTU domain with irreversibly oxidised Cys103 from 60 min H2O2 soak. | 分子名称: | CHLORIDE ION, TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 | 著者 | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | 登録日 | 2013-01-17 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation Nat.Commun., 4, 2013
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3ZJD
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![BU of 3zjd by Molmil](/molmil-images/mine/3zjd) | A20 OTU domain in reduced, active state at 1.87 A resolution | 分子名称: | 1,2-ETHANEDIOL, A20P50, CHLORIDE ION | 著者 | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | 登録日 | 2013-01-17 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation Nat.Commun., 4, 2013
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3ZJF
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![BU of 3zjf by Molmil](/molmil-images/mine/3zjf) | A20 OTU domain with irreversibly oxidised Cys103 from 270 min H2O2 soak. | 分子名称: | A20P50, CHLORIDE ION | 著者 | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | 登録日 | 2013-01-17 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation Nat.Commun., 4, 2013
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2GOY
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![BU of 2goy by Molmil](/molmil-images/mine/2goy) | Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS | 分子名称: | ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, adenosine phosphosulfate reductase | 著者 | Chartron, J, Carroll, K.S, Shiau, C, Gao, H, Leary, J.A, Bertozzi, C.R, Stout, C.D. | 登録日 | 2006-04-14 | 公開日 | 2006-09-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase. J.Mol.Biol., 364, 2006
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2O8V
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![BU of 2o8v by Molmil](/molmil-images/mine/2o8v) | PAPS reductase in a covalent complex with thioredoxin C35A | 分子名称: | Phosphoadenosine phosphosulfate reductase, Thioredoxin 1 | 著者 | Chartron, J, Shiau, C, Stout, C.D, Carroll, K.S. | 登録日 | 2006-12-12 | 公開日 | 2007-03-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | 3'-Phosphoadenosine-5'-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle. Biochemistry, 46, 2007
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2QVI
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