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PDB: 32 件

6HBS
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Structure of PLP internal aldimine form of Sphingopyxis sp. MTA144 FumI protein
分子名称: Aminopentol aminotransferase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE
著者Campopiano, D.J, Serpico, A, Marles-Wright, J.
登録日2018-08-13
公開日2019-08-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of PLP internal aldimine form of Sphingopyxis sp. MTA144 FumI protein
To Be Published
6HBV
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Structure of PLP internal aldimine form of Sphingopyxis sp. MTA144 FumI protein
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aminopentol aminotransferase, MAGNESIUM ION, ...
著者Campopiano, D.J, Serpico, A, Marles-Wright, J.
登録日2018-08-13
公開日2019-08-28
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of PLP internal aldimine form of Sphingopyxis sp. MTA144 FumI protein
To Be Published
1XC1
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Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP)
分子名称: OXO ZIRCONIUM(IV) CLUSTER, periplasmic iron-binding protein
著者Zhong, W, Alexeev, D, Harvey, I, Guo, M, Hunter, D.J.B, Zhu, H, Campopiano, D.J, Sadler, P.J.
登録日2004-08-31
公開日2004-09-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft
Angew.Chem.Int.Ed.Engl., 43, 2004
4TQX
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BU of 4tqx by Molmil
Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone.
分子名称: ACETIC ACID, SULFATE ION, Sortase, ...
著者Wallock-Richards, D.J, Marles-Wright, J, Clarke, D.J, Maitra, A, Dodds, M, Hanley, B, Campopiano, D.J.
登録日2014-06-12
公開日2015-05-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone.
Chem.Commun.(Camb.), 51, 2015
1O7T
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Metal nanoclusters bound to the Ferric Binding Protein from Neisseria gonorrhoeae.
分子名称: HF OXO CLUSTER HF5, HF-OXO-PHOSPHATE CLUSTER PHF, IRON BINDING PROTEIN, ...
著者Alexeev, D, Zu, H, Guo, M, Zhong, W, Hunter, D.J.B, Yang, W, Campopiano, D.J, Sadler, P.J.
登録日2002-11-12
公開日2003-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A novel protein-mineral interface.
Nat. Struct. Biol., 10, 2003
2X8U
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Sphingomonas wittichii Serine palmitoyltransferase
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2010-03-12
公開日2010-03-23
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Serine Palmitoyltransferase from Sphingomonas Wittichii Rw1 an Interesting Link to an Unusual Acyl Carrier Protein
Biopolymers, 93, 2010
1DJ9
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BU of 1dj9 by Molmil
CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY.
分子名称: 8-AMINO-7-OXONONANOATE SYNTHASE, MAGNESIUM ION, N-[7-KETO-8-AMINOPELARGONIC ACID]-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ...
著者Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L.
登録日1999-12-02
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
1DJE
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BU of 1dje by Molmil
CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE
分子名称: 8-AMINO-7-OXONANOATE SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L.
登録日1999-12-02
公開日2000-12-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
2W8J
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SPT with PLP-ser
分子名称: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
著者Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-16
公開日2009-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8T
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SPT with PLP, N100C
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8V
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SPT with PLP, N100W
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8U
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SPT with PLP, N100Y
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8W
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N100Y SPT with PLP-ser
分子名称: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2XBN
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BU of 2xbn by Molmil
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE
著者Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J.
登録日2010-04-13
公開日2010-05-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
1R1N
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BU of 1r1n by Molmil
Tri-nuclear oxo-iron clusters in the ferric binding protein from N. gonorrhoeae
分子名称: Ferric-iron Binding Protein, OXO-IRON CLUSTER 1, OXO-IRON CLUSTER 2, ...
著者Zhu, H, Alexeev, D, Hunter, D.J, Campopiano, D.J, Sadler, P.J.
登録日2003-09-24
公開日2004-03-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.
Biochem.J., 376, 2003
5K1R
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BU of 5k1r by Molmil
Structure of Burkholderia pseudomallei K96243 sphingosine-1-phosphate lyase Bpss2021
分子名称: Burkholderia pseudomallei sphingosine-1-phosphate lyase Bpss2021, PYRIDOXAL-5'-PHOSPHATE
著者Mclean, C.J, Campopiano, D.J, Marles-Wright, J.
登録日2016-05-18
公開日2016-11-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei.
J. Lipid Res., 58, 2017
6G1F
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Crystal structure of D-phenylglycine aninotransferase (D-PhgAT) from Pseudomonas stutzeri with PLP internal aldimine
分子名称: D-phenylglycine aminotransferase
著者Serpico, A, Marles-Wright, J, Campopiano, D.J.
登録日2018-03-21
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献D-Phenylglycine aminotransferase (D-PhgAT) – substrate scope and structural insights of a stereo-inverting biocatalyst used in the preparation of aromatic amino acids
Catalysis Science And Technology, 2020
1BS0
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BU of 1bs0 by Molmil
PLP-DEPENDENT ACYL-COA SYNTHASE
分子名称: PROTEIN (8-AMINO-7-OXONANOATE SYNTHASE), SULFATE ION
著者Alexeev, D, Alexeeva, M, Baxter, R.L, Campopiano, D.J, Webster, S.P, Sawyer, L.
登録日1998-08-31
公開日1999-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
J.Mol.Biol., 284, 1998
4BMK
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Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine
分子名称: Decarboxylated Myriocin, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wadsworth, J.M, Clarke, D.J, McMahon, S.A, Beattie, A.E, Lowther, J, Dunn, T.M, Naismith, J.H, Campopiano, D.J.
登録日2013-05-09
公開日2013-09-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin.
J.Am.Chem.Soc., 135, 2013
3EFR
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Biotin protein ligase R40G mutant from Aquifex aeolicus in complex with biotin
分子名称: BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION
著者Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J.
登録日2008-09-10
公開日2009-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
3EFS
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BU of 3efs by Molmil
Biotin protein ligase from Aquifex aeolicus in complex with biotin and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, ...
著者Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J.
登録日2008-09-10
公開日2009-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
3FJP
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Apo structure of Biotin protein ligase from Aquifex aeolicus
分子名称: Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION
著者McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J.
登録日2008-12-15
公開日2009-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
4A6G
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N-acyl amino acid racemase from Amycalotopsis sp. Ts-1-60: G291D- F323Y mutant in complex with N-acetyl methionine
分子名称: MAGNESIUM ION, N-ACETYLMETHIONINE, N-ACYLAMINO ACID RACEMASE
著者Baxter, S, Royer, S, Grogan, G, Holt-Tiffin, K.E, Taylor, I.N, Fotheringham, I.G, Campopiano, D.J.
登録日2011-11-02
公開日2012-11-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献An Improved Racemase/Acylase Biotransformation for the Preparation of Enantiomerically Pure Amino Acids.
J.Am.Chem.Soc., 134, 2012
5DRU
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Structure of His387Ala mutant of the propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment
分子名称: Aldehyde Dehydrogenase, SULFATE ION
著者Tuck, L.R, Altenbach, K, Fu, A.T, Crawshaw, A.D, Campopiano, D.J, Clarke, D.J, Marles-Wright, J.
登録日2015-09-16
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.083 Å)
主引用文献Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.
Sci Rep, 6, 2016
5DBV
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Structure of a C269A mutant of propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment
分子名称: ACETATE ION, Aldehyde Dehydrogenase, COENZYME A, ...
著者Tuck, L.R, Altenbach, K, Ang, T.F, Crawshaw, A.D, Campopiano, D.J, Clarke, D.J, Marles-Wright, J.
登録日2015-08-22
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.
Sci Rep, 6, 2016

 

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