6KYC
| Structure of the S207A mutant of Clostridium difficile sortase B | Descriptor: | Putative peptidase C60B, sortase B | Authors: | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | Deposit date: | 2019-09-17 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity. J.Biol.Chem., 295, 2020
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6KYD
| Structure of the R217A mutant of Clostridium difficile sortase B | Descriptor: | Putative peptidase C60B, sortase B | Authors: | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | Deposit date: | 2019-09-18 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity. J.Biol.Chem., 295, 2020
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6S9O
| Designed Armadillo Repeat protein internal Lock1 fused to target peptide KRKRKLKFKR | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, designed Armadillo repeat protein with internal Lock1 fused to target peptide KRKRKLKFKR | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | Deposit date: | 2019-07-15 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15, 2020
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8HBC
| Crystal structure of the CysR-CTLD3 fragment of human DEC205 | Descriptor: | Lymphocyte antigen 75 | Authors: | Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y. | Deposit date: | 2022-10-28 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Interaction of human dendritic cell receptor DEC205/CD205 with keratins. J.Biol.Chem., 300, 2024
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4R1Y
| Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitor | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 3-(diethylamino)propyl (3-{[5-(3,4-dimethoxyphenyl)-2-oxo-2H-1,3,4-thiadiazin-3(6H)-yl]methyl}phenyl)carbamate, Hepatocyte growth factor receptor | Authors: | Blaukat, A, Bladt, F, Friese-Hamim, M, Knuehl, C, Fittschen, C, Graedler, U, Meyring, M, Dorsch, D, Stieber, F, Schadt, O. | Deposit date: | 2014-08-08 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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6S9N
| Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKLSF | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKLSF | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | Deposit date: | 2019-07-15 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15, 2020
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4R1V
| Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors | Descriptor: | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | Authors: | Blaukat, A, Bladt, F, Friese-Hamim, M, Knuehl, C, Fittschen, C, Graedler, U, Meyring, M, Dorsch, D, Stieber, F, Schadt, O. | Deposit date: | 2014-08-07 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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7AZ9
| Perdeuterated E65Q-TIM complexed with PHOSPHOGLYCOLOHYDROXAMATE | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Triosephosphate isomerase | Authors: | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | Deposit date: | 2020-11-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | Cite: | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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7AZA
| Perdeuterated E65Q-TIM complexed with PHOSPHOGLYCOLOHYDROXAMATE | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Triosephosphate isomerase | Authors: | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | Deposit date: | 2020-11-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | Cite: | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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5AEI
| Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5 | Descriptor: | ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ... | Authors: | Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A. | Deposit date: | 2015-08-31 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity. J.Am.Chem.Soc., 138, 2016
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6JLI
| Crystal structure of CTLD7 domain of human PLA2R | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor | Authors: | Yu, B, Hu, Z, Kong, D, Cheng, C, He, Y. | Deposit date: | 2019-03-06 | Release date: | 2019-07-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.778 Å) | Cite: | Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor. J.Struct.Biol., 207, 2019
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6ST7
| Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp | Descriptor: | ISOPROPYL ALCOHOL, TRYPTOPHAN, Trp operon repressor | Authors: | Sprenger, J, Lawson, C.L, Carey, J, Drouard, F, von Wachenfeldt, C, Schulz, A, Linse, S, Lo Leggio, L. | Deposit date: | 2019-09-10 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan. Acta Crystallogr.,Sect.F, 77, 2021
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6ST6
| Crystal Structure of Domain Swapped Trp Repressor V58I Variant | Descriptor: | ISOPROPYL ALCOHOL, Trp operon repressor | Authors: | Sprenger, J, Lawson, C.L, Carey, J, Drouard, F, von Wachenfeldt, C, Schulz, A, Linse, S, Lo Leggio, L. | Deposit date: | 2019-09-10 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan. Acta Crystallogr.,Sect.F, 77, 2021
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5BN3
| Structure of a unique ATP synthase NeqA-NeqB in complex with ADP from Nanoarcheaum equitans | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-25 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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5BN4
| Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans | Descriptor: | MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-25 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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7ABX
| Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase | Authors: | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | Deposit date: | 2020-09-09 | Release date: | 2021-07-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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6S9L
| Designed Armadillo Repeat protein Lock1 bound to (KR)4KLSF target | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, KR4KLSF Lock1, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-LEU-SER-PHE | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | Deposit date: | 2019-07-15 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15, 2020
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6S9M
| Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ... | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | Deposit date: | 2019-07-15 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15, 2020
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7AZ3
| Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase | Authors: | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | Deposit date: | 2020-11-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.15 Å), X-RAY DIFFRACTION | Cite: | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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7AZ4
| Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase | Authors: | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | Deposit date: | 2020-11-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.15 Å), X-RAY DIFFRACTION | Cite: | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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7QO4
| 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) | Descriptor: | 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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5BN5
| Structural basis for a unique ATP synthase core complex from Nanoarcheaum equitans | Descriptor: | NEQ263, SULFATE ION, V-type ATP synthase alpha chain | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-25 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.997 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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5BO5
| Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans | Descriptor: | MAGNESIUM ION, NEQ263, SULFATE ION | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-27 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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6GHO
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5E26
| Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | DONG, A, LOPPNAU, P, RAVICHANDRAN, M, CHENG, C, TEMPEL, W, SEITOVA, A, HUTCHINSON, A, HONG, B.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2015-09-30 | Release date: | 2015-10-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate to be published
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