3J2T
| An improved model of the human apoptosome | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | 著者 | Yuan, S, Topf, M, Akey, C.W. | 登録日 | 2012-12-23 | 公開日 | 2013-04-10 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Changes in apaf-1 conformation that drive apoptosome assembly. Biochemistry, 52, 2013
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4WLR
| Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | 分子名称: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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4A8J
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3MAY
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4ZQA
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4ZQW
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4ZQU
| CdiA-CT/CdiI toxin and immunity complex from Yersinia pseudotuberculosis | 分子名称: | CHLORIDE ION, CdiA-CT toxin, Conserved domain protein, ... | 著者 | Morse, R.P, Johnson, P.M, Credali, A, Goulding, C.W. | 登録日 | 2015-05-11 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Diversification of beta-Augmentation Interactions between CDI Toxin/Immunity Proteins. J.Mol.Biol., 427, 2015
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3NG2
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5V1Y
| Crystal structure of the ternary RPN13 PRU-RPN2 (940-953)-ubiquitin complex | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | 著者 | Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P. | 登録日 | 2017-03-02 | 公開日 | 2017-05-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | 主引用文献 | Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism. J. Biol. Chem., 292, 2017
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5VJB
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5VJ9
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3NME
| Structure of a plant phosphatase | 分子名称: | PHOSPHATE ION, SEX4 glucan phosphatase | 著者 | Vander Kooi, C.W. | 登録日 | 2010-06-22 | 公開日 | 2010-08-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the glucan phosphatase activity of Starch Excess4. Proc.Natl.Acad.Sci.USA, 107, 2010
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3OD9
| Crystal structure of PliI-Ah, periplasmic lysozyme inhibitor of I-type lysozyme from Aeromonas hydrophyla | 分子名称: | POTASSIUM ION, Putative exported protein, SODIUM ION | 著者 | Leysen, S, Van Herreweghe, J.M, Callewaert, L, Heirbaut, M, Buntinx, P, Michiels, C.W, Strelkov, S.V. | 登録日 | 2010-08-11 | 公開日 | 2010-12-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.411 Å) | 主引用文献 | Molecular Basis of Bacterial Defense against Host Lysozymes: X-ray Structures of Periplasmic Lysozyme Inhibitors PliI and PliC. J.Mol.Biol., 405, 2011
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3QLL
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3QTF
| Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity | 分子名称: | (6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-8,12-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha | 著者 | Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Nittoli, T, Ingalls, C, Sutherland, A.G, Sonye, J.P, Eid, C.N, Golas, J, Liu, H, Boschelli, F, Hu, Y, Vogan, E.M, Levin, J.I. | 登録日 | 2011-02-22 | 公開日 | 2011-04-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5703 Å) | 主引用文献 | Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity. Bioorg.Med.Chem.Lett., 21, 2011
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3QLI
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4EHY
| Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. | 登録日 | 2012-04-04 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
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4D4Q
| Crystal Structure of Kti13/AtS1 | 分子名称: | PROTEIN ATS1 | 著者 | Glatt, S, Mueller, C.W. | 登録日 | 2014-10-30 | 公開日 | 2015-01-14 | 最終更新日 | 2017-03-29 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Structure of the Kti11/Kti13 Heterodimer and its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2. Structure, 23, 2015
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5FLV
| Crystal structure of NKX2-5 and TBX5 bound to the Nppa promoter region | 分子名称: | 5'-D(*AP*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP *GP*TP*GP*AP*GP*AP*AP*G)-3', 5'-D(*TP*CP*TP*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP *TP*GP*AP*AP*GP*TP*GP*G)-3', HOMEOBOX PROTEIN NKX-2.5, ... | 著者 | Stirnimann, C.U, Glatt, S, Mueller, C.W. | 登録日 | 2015-10-28 | 公開日 | 2016-02-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell(Cambridge,Mass.), 164, 2016
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4EHW
| Crystal structure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Tetraacyldisaccharide 4'-kinase | 著者 | Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. | 登録日 | 2012-04-04 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
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6SPZ
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1PFS
| SOLUTION NMR STRUCTURE OF THE SINGLE-STRANDED DNA BINDING PROTEIN OF THE FILAMENTOUS PSEUDOMONAS PHAGE PF3, MINIMIZED AVERAGE STRUCTURE | 分子名称: | PF3 SINGLE-STRANDED DNA BINDING PROTEIN | 著者 | Folmer, R.H.A, Nilges, M, Konings, R.N.H, Hilbers, C.W. | 登録日 | 1996-08-03 | 公開日 | 1997-02-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the single-stranded DNA binding protein of the filamentous Pseudomonas phage Pf3: similarity to other proteins binding to single-stranded nucleic acids. EMBO J., 14, 1995
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6SPV
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4EHX
| Crystal structure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. | 登録日 | 2012-04-04 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
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4D4O
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