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PDB: 2172 results

2YEK
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Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GSK525762 (IBET)
Descriptor: 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide, BROMODOMAIN-CONTAINING PROTEIN 2, SULFATE ION
Authors:Chung, C.W.
Deposit date:2011-03-25
Release date:2011-06-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
J.Med.Chem., 54, 2011
2YN0
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tau55 histidine phosphatase domain
Descriptor: PHOSPHATE ION, TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT
Authors:Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W.
Deposit date:2012-10-11
Release date:2013-04-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Iiic.
J.Biol.Chem., 288, 2013
1I6M
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1.7 HIGH RESOLUTION EXPERIMENTAL PHASES FOR TRYPTOPHANYL-TRNA SYNTHETASE COMPLEXED WITH TRYPTOPHANYL-5'AMP
Descriptor: AMMONIUM ION, GLYCEROL, SULFATE ION, ...
Authors:Retailleau, P, Carter, C.W.
Deposit date:2001-03-02
Release date:2001-11-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP.
Acta Crystallogr.,Sect.D, 57, 2001
1J98
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The 1.2 Angstrom Structure of Bacillus subtilis LuxS
Descriptor: AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION
Authors:Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2001-05-24
Release date:2001-06-06
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A Structure of a Novel Quorum-Sensing Protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1K9G
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Crystal Structure of the Complex of Cryptolepine-d(CCTAGG)2
Descriptor: 5'-D(*CP*CP*TP*AP*GP*G)-3', 5-METHYL-5H-INDOLO[3,2-B]QUINOLINE
Authors:Lisgarten, J.N, Coll, M, Portugal, J, Wright, C.W, Aymami, J.
Deposit date:2001-10-29
Release date:2001-11-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites.
Nat.Struct.Biol., 9, 2002
1K79
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Ets-1(331-440)+GGAA duplex
Descriptor: C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3')
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1KSO
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CRYSTAL STRUCTURE OF APO S100A3
Descriptor: S100 CALCIUM-BINDING PROTEIN A3
Authors:Mittl, P.R, Fritz, G, Sargent, D.F, Richmond, T.J, Heizmann, C.W, Grutter, M.G.
Deposit date:2002-01-14
Release date:2002-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal-free MIRAS phasing: structure of apo-S100A3.
Acta Crystallogr.,Sect.D, 58, 2002
1JQW
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THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Autoinducer-2 production protein luxS, ZINC ION
Authors:Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2001-08-09
Release date:2001-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1JVI
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THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX
Descriptor: (2S)-2-amino-4-[[(2S,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methylsulfanyl]butanoic acid, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Autoinducer-2 production protein luxS, ...
Authors:Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2001-08-30
Release date:2001-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1KG1
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NMR structure of the NIP1 elicitor protein from Rhynchosporium secalis
Descriptor: Necrosis Inducing Protein 1
Authors:Van't Slot, K.A, Van den Burg, H.A, Kloks, C.P, Hilbers, C.W, Knogge, W, Papavoine, C.H.
Deposit date:2001-11-26
Release date:2003-11-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure of the Plant Disease Resistance-triggering Protein NIP1 from the Fungus Rhynchosporium secalis Shows a Novel beta-Sheet Fold.
J.Biol.Chem., 278, 2003
1I6K
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1.7 HIGH RESOLUTION EXPERIMENTAL PHASES FOR TRYPTOPHANYL-TRNA SYNTHETASE COMPLEXED WITH TRYPTOPHANYL-5'AMP
Descriptor: AMMONIUM ION, GLYCEROL, SULFATE ION, ...
Authors:Retailleau, P, Carter, C.W.
Deposit date:2001-03-02
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP.
Acta Crystallogr.,Sect.D, 57, 2001
1I6L
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BU of 1i6l by Molmil
1.7 HIGH RESOLUTION EXPERIMENTAL PHASES FOR TRYPTOPHANYL-TRNA SYNTHETASE COMPLEXED WITH TRYPTOPHANYL-5'AMP
Descriptor: AMMONIUM ION, GLYCEROL, SULFATE ION, ...
Authors:Retailleau, P, Carter, C.W.
Deposit date:2001-03-02
Release date:2001-11-07
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP.
Acta Crystallogr.,Sect.D, 57, 2001
1K7A
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Ets-1(331-440)+GGAG duplex
Descriptor: C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3')
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K5J
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The Crystal Structure of Nucleoplasmin-Core
Descriptor: Nucleoplasmin Core
Authors:Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W.
Deposit date:2001-10-10
Release date:2001-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.
Mol.Cell, 8, 2001
1K78
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Pax5(1-149)+Ets-1(331-440)+DNA
Descriptor: C-ets-1 Protein, Paired Box Protein Pax5, Pax5/Ets Binding Site on the mb-1 promoter
Authors:Garvie, C.W, Hagman, J, Wolberger, C.
Deposit date:2001-10-18
Release date:2002-01-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1LU4
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1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS
Descriptor: SOLUBLE SECRETED ANTIGEN MPT53
Authors:Goulding, C.W, Apostol, M.I, Gleiter, S, Parseghian, A, Bardwell, J, Gennaro, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-21
Release date:2003-10-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Gram-positive DsbE Proteins Function Differently from Gram-negative DsbE Homologs: A STRUCTURE TO FUNCTION ANALYSIS OF DsbE FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 279, 2004
1L6P
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N-terminal of DsbD (residues 20-144) from E. coli.
Descriptor: Thiol:disulfide interchange protein dsbD
Authors:Goulding, C.W, Sawaya, M.R, Parseghian, A.
Deposit date:2002-03-12
Release date:2002-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD.
Biochemistry, 41, 2002
1L7I
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Crystal Structure of the anti-ErbB2 Fab2C4
Descriptor: SULFATE ION, chimera of Fab2C4: "humanized" murine monoclonal antibody
Authors:Vajdos, F.F, Adams, C.W, Breece, T.N, Presta, L.G, de Vos, A.M, Sidhu, S.S.
Deposit date:2002-03-15
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
J.Mol.Biol., 320, 2002
1LA4
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Solution Structure of SGTx1
Descriptor: SGTx1
Authors:Lee, C.W, Roh, S.H, Kim, S, Endoh, H, Kodera, Y, Maeda, T, Swartz, K.J, Kim, J.I.
Deposit date:2002-03-28
Release date:2003-11-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating
Biochemistry, 43, 2004
1IE6
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SOLUTION STRUCTURE OF IMPERATOXIN A
Descriptor: IMPERATOXIN A
Authors:Lee, C.W, Takeuchi, K, Takahashi, H, Sato, K, Shimada, I, Kim, D.H, Kim, J.I.
Deposit date:2001-04-07
Release date:2003-06-10
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Molecular basis of the high-affinity activation of type 1 ryanodine receptors by imperatoxin A.
Biochem.J., 377, 2004
1LU8
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Solution structure of GsMTx-4
Descriptor: venom toxin peptide MTx4
Authors:Jung, H.J, Lee, C.W, Earm, Y.E, Kim, J.I.
Deposit date:2002-05-22
Release date:2004-01-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of GsMTx-4, a peptide blocker of cation-selective stretch-activated channels
To be Published
1LMI
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1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63
Descriptor: Immunogenic protein MPT63/MPB63
Authors:Goulding, C.W, Parseghian, A, Sawaya, M.R, Cascio, D, Apostol, M, Gennaro, M.L, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-01
Release date:2002-12-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution
Protein Sci., 11, 2002
1LQB
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Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex
Descriptor: Elongin B, Elongin C, Hypoxia-inducible factor 1 ALPHA, ...
Authors:Hon, W.C, Wilson, M.I, Harlos, K, Claridge, T.D, Schofield, C.J, Pugh, C.W, Maxwell, P.H, Ratcliffe, P.J, Stuart, D.I, Jones, E.Y.
Deposit date:2002-05-09
Release date:2002-07-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
Nature, 417, 2002
1MJP
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METHIONINE APOREPRESSOR MUTANT (Q44K) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR
Descriptor: CONSENSUS OPERATOR DUPLEX, METHIONINE REPRESSOR
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-29
Release date:1999-08-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJL
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METHIONINE REPRESSOR MUTANT (Q44K) COMPLEX WITH THE COREPRESSOR SAM (S-ADENOSYL METHIONINE) FROM ESCHERICHIA COLI
Descriptor: METHIONINE REPRESSOR PROTEIN METJ, S-ADENOSYLMETHIONINE
Authors:Garvie, C.W, Phillips, S.E.V.
Deposit date:1998-01-26
Release date:1998-04-29
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic studies of the methionine repressor-operator complex and the oc31 42kDa repressor
Thesis, University of Leeds, 1997

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