5J9B
| Crystal structure of peroxiredoxin Asp f3 | Descriptor: | peroxiredoxin Asp f3 | Authors: | Bzymek, K.P, Williams, J.C, Hong, T.B, Bagramyan, K, Kalkum, M. | Deposit date: | 2016-04-08 | Release date: | 2016-09-21 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus. Sci Rep, 6, 2016
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3UEP
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5T1K
| Cetuximab Fab in complex with CQFDA(Ph)2STRRLKC | Descriptor: | CETUXIMAB FAB HEAVY CHAIN, CETUXIMAB FAB LIGHT CHAIN, CQFDA(PH)2STRRLKC PEPTIDE, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-08-19 | Release date: | 2016-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5T1M
| Cetuximab Fab in complex with CQYDLSTRRLKC | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CETUXIMAB FAB HEAVY CHAIN, CETUXIMAB FAB LIGHT CHAIN, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-08-19 | Release date: | 2016-10-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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2ANP
| Functional Glutamate 151 to Histidine mutant of the aminopeptidase from Aeromonas Proteolytica. | Descriptor: | SODIUM ION, ZINC ION, leucyl aminopeptidase | Authors: | Bzymek, K.P, Moulin, A, Swierczek, S.I, Ringe, D, Petsko, G.A, Holz, R.C. | Deposit date: | 2005-08-11 | Release date: | 2005-10-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic, Spectroscopic, and X-ray Crystallographic Characterization of the Functional E151H Aminopeptidase from Aeromonas proteolytica. Biochemistry, 44, 2005
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5J9C
| Crystal structure of peroxiredoxin Asp f3 C31S/C61S variant | Descriptor: | MAGNESIUM ION, peroxiredoxin Asp f3 | Authors: | Bzymek, K.P, Williams, J.C, Hong, T.B, Bagramyan, K, Kalkum, M. | Deposit date: | 2016-04-08 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.956 Å) | Cite: | The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus. Sci Rep, 6, 2016
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5IV2
| Cetuximab Fab in complex with Arg9Cir meditope variant | Descriptor: | Cetuximab Fab, heavy chain, light chain, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-03-18 | Release date: | 2016-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.481 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5IVZ
| Cetuximab Fab in complex with Arg8Cir meditope variant | Descriptor: | Cetuximab Fab, heavy chain, light chain, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-03-21 | Release date: | 2016-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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4IOI
| Meditope-enabled trastuzumab in complex with CQFDLSTRRLKC | Descriptor: | Immunoglobulin G-binding protein A, Protein L, Trastuzumab heavy chain, ... | Authors: | Bzymek, K.P, Zer, C, Avery, K.N, Williams, J.C. | Deposit date: | 2013-01-07 | Release date: | 2013-10-09 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KAQ
| Structure of rituximab Fab | Descriptor: | Rituximab heavy chain, Rituximab light chain | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2013-04-22 | Release date: | 2014-12-24 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structure of rituximab To be Published
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5ESQ
| Cetuximab Fab in complex with cyclic beta-alanine-linked meditope | Descriptor: | Cetuximab Fab heavy chain, Cetuximab Fab light chain, Cyclic beta-alanine-linked meditope, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2015-11-16 | Release date: | 2016-06-15 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5ETU
| Cetuximab Fab in complex with L5E meditope variant | Descriptor: | Cetuximab Fab heavy chain, Cetuximab Fab light chain, L5E meditope variant, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2015-11-18 | Release date: | 2016-10-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5EUK
| Cetuximab Fab in complex with F3H meditope variant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2015-11-18 | Release date: | 2016-10-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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6AU5
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6AYN
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6AZK
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6AXP
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6BAH
| Trastuzumab Fab v3 with 5-diphenyl meditope variant | Descriptor: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ... | Authors: | Bzymek, K.P, King, J.D, Williams, J.C. | Deposit date: | 2017-10-12 | Release date: | 2018-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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6AZL
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6BAE
| Trastuzumab Fab v3 in complex with CQFDLSTRRLKC | Descriptor: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | Authors: | Bzymek, K.P, King, J.D, Williams, J.C. | Deposit date: | 2017-10-12 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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6B9Z
| Trastuzumab Fab v3 | Descriptor: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | Authors: | Bzymek, K.P, King, J.D, Williams, J.C. | Deposit date: | 2017-10-11 | Release date: | 2018-09-05 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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6B9Y
| Trastuzumab Fab v3 in complex with 5-phenyl meditope variant | Descriptor: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | Authors: | Bzymek, K.P, King, J.D, Williams, J.C. | Deposit date: | 2017-10-11 | Release date: | 2018-09-05 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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5TH2
| Cetuximab Fab in complex with L5Q meditope variant | Descriptor: | L5Q meditope, PHOSPHATE ION, cetuximab Fab, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-09-28 | Release date: | 2016-10-26 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5U5F
| MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT IN COMPLEX WITH (Ac) CQFDA(PH)2STRRLRCGGSK | Descriptor: | 5-DIPHENYL LONG MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB FAB HEAVY CHAIN, ... | Authors: | Bzymek, K.P, Avery, K.N, Zer, C, Williams, J.C. | Deposit date: | 2016-12-06 | Release date: | 2018-03-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Meditope Enabled Trastuzumab I83E Variant In Complex With (Ac)Cqfda(Ph)2Strrlrcggsk To Be Published
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5T1L
| Cetuximab Fab in complex with CQA(Ph)2DLSTRRLKC peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CETUXIMAB FAB HEAVY CHAIN, CETUXIMAB FAB LIGHT CHAIN, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2016-08-19 | Release date: | 2016-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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