5ESQ
Cetuximab Fab in complex with cyclic beta-alanine-linked meditope
Summary for 5ESQ
| Entry DOI | 10.2210/pdb5esq/pdb |
| Related | 1YY8 4GW1 4HEK |
| Descriptor | Cetuximab Fab light chain, Cetuximab Fab heavy chain, Cyclic beta-alanine-linked meditope, ... (5 entities in total) |
| Functional Keywords | antibody, anti-egfr, immune system |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 6 |
| Total formula weight | 97413.50 |
| Authors | Bzymek, K.P.,Williams, J.C. (deposition date: 2015-11-16, release date: 2016-06-15, Last modification date: 2017-12-13) |
| Primary citation | Bzymek, K.P.,Ma, Y.,Avery, K.A.,Horne, D.A.,Williams, J.C. Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72:434-442, 2016 Cited by PubMed: 27303895DOI: 10.1107/S2053230X16007202 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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