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PDB: 119 results

8QJ2
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BU of 8qj2 by Molmil
Structure of active state MC4R in complex with a potent ligand mimicking nanobody
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Busch, A, Jaakola, V.-P, Masiulis, S.
Deposit date:2023-09-12
Release date:2024-09-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of active state MC4R in complex with a potent ligand mimicking nanobody
To Be Published
2X9O
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STRUCTURE OF 15, 16- DIHYDROBILIVERDIN:FERREDOXIN OXIDOREDUCTASE (PebA)
Descriptor: 15,16-DIHYDROBILIVERDIN-FERREDOXIN OXIDOREDUCTASE, BILIVERDINE IX ALPHA
Authors:Busch, A.W.U, Frankenberg-Dinkel, N, Hofmann, E.
Deposit date:2010-03-23
Release date:2011-03-30
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural and Mechanistic Insight Into the Ferredoxin-Mediated Two-Electron Reduction of Bilins.
Biochem.J., 439, 2011
2X9J
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Structure of the Mutant D206N of Phycoerythrobilin Synthase PebS from the Cyanophage P-SSM2 in complex with bound substrate Biliverdin IXA
Descriptor: BILIVERDINE IX ALPHA, PHYCOERYTHROBILIN SYNTHASE
Authors:Busch, A.W.U, Frankenberg-Dinkel, N, Hofmann, E.
Deposit date:2010-03-21
Release date:2010-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Radical Mechanism of Cyanophage Phycoerythrobilin Synthase (Pebs).
Biochem.J., 433, 2011
2X9I
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Structure of the Mutant D105N of Phycoerythrobilin Synthase PebS from the Cyanophage P-SSM2 in complex with bound substrate Biliverdin IXA
Descriptor: BILIVERDINE IX ALPHA, PHYCOBILIN SYNTHASE, SULFATE ION
Authors:Busch, A.W.U, Frankenberg-Dinkel, N, Hofmann, E.
Deposit date:2010-03-20
Release date:2010-11-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Radical Mechanism of Cyanophage Phycoerythrobilin Synthase (Pebs).
Biochem.J., 433, 2011
2LIU
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BU of 2liu by Molmil
NMR structure of holo-ACPI domain from CurA module from Lyngbya majuscula
Descriptor: CurA
Authors:Busche, A.E, Gottstein, D, Hein, C, Ripin, N, Pader, I, Tufar, P, Eisman, E.B, Gu, L, Walsh, C.T, Loehr, F, Sherman, D.H, Guntert, P, Dotsch, V.
Deposit date:2011-09-01
Release date:2011-12-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase.
Acs Chem.Biol., 7, 2012
2LIW
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BU of 2liw by Molmil
NMR structure of HMG-ACPI domain from CurA module from Lyngbya majuscula
Descriptor: 3-HYDROXY-3-METHYL-GLUTARIC ACID, 4'-PHOSPHOPANTETHEINE, CurA
Authors:Busche, A.E, Gottstein, D, Hein, C, Ripin, N, Pader, I, Tufar, P, Eisman, E.B, Gu, L, Walsh, C.T, Loehr, F, Sherman, D.H, Guntert, P, Dotsch, V.
Deposit date:2011-09-01
Release date:2011-12-21
Last modified:2012-03-14
Method:SOLUTION NMR
Cite:Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase.
Acs Chem.Biol., 7, 2012
1RZU
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BU of 1rzu by Molmil
Crystal structure of the glycogen synthase from A. tumefaciens in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase 1
Authors:Buschiazzo, A, Guerin, M.E, Ugalde, J.E, Ugalde, R.A, Shepard, W, Alzari, P.M.
Deposit date:2003-12-29
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.
Embo J., 23, 2004
1W61
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proline racemase in complex with 2 molecules of pyrrole-2-carboxylic acid (holo form)
Descriptor: B-CELL MITOGEN, PYRROLE-2-CARBOXYLATE
Authors:Buschiazzo, A, Alzari, P.
Deposit date:2004-08-11
Release date:2006-02-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure,Catalytic Mechanism and Mitogenic Properties of Trypanosoma Cruzi Proline Racemase
Proc.Natl.Acad.Sci.USA, 103, 2006
5K0W
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BU of 5k0w by Molmil
Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica
Descriptor: CHLORIDE ION, Class B carbapenemase GOB-18, GLYCEROL, ...
Authors:Buschiazzo, A, Larrieux, N, Vila, A.J, Lisa, M.N, Moran-Barrio, J.
Deposit date:2016-05-17
Release date:2016-08-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.
Antimicrob.Agents Chemother., 60, 2016
1W62
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BU of 1w62 by Molmil
proline racemase in complex with one molecule of pyrrole-2-carboxylic acid (hemi form)
Descriptor: PYRROLE-2-CARBOXYLATE, Proline racemase A
Authors:Buschiazzo, A, Alzari, P.
Deposit date:2004-08-12
Release date:2006-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
3M8O
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BU of 3m8o by Molmil
Human IgA1 Fab fragment
Descriptor: CHLORIDE ION, GLYCEROL, IMMUNOGLOBULIN A1 HEAVY CHAIN, ...
Authors:Buschiazzo, A, Trajtenberg, F, Correa, A, Oppezzo, P, Pritsch, O, Dighiero, G.
Deposit date:2010-03-18
Release date:2011-03-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation
Acta Crystallogr.,Sect.D, 69, 2013
3B69
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BU of 3b69 by Molmil
T cruzi Trans-sialidase complex with benzoylated NANA derivative
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-acetamido-9-(benzoylamino)-3,5,9-trideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, ...
Authors:Buschiazzo, A.
Deposit date:2007-10-28
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:A new generation of specific Trypanosoma cruzi trans-sialidase inhibitors.
Angew.Chem.Int.Ed.Engl., 47, 2008
1RZV
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BU of 1rzv by Molmil
Crystal structure of the glycogen synthase from Agrobacterium tumefaciens (non-complexed form)
Descriptor: Glycogen synthase 1
Authors:Buschiazzo, A, Guerin, M.E, Ugalde, J.E, Ugalde, R.A, Shepard, W, Alzari, P.M.
Deposit date:2003-12-29
Release date:2004-08-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.
Embo J., 23, 2004
2F41
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Crystal structure of FapR- a global regulator of fatty acid biosynthesis in B. subtilis
Descriptor: Transcription factor fapR
Authors:Buschiazzo, A, Guerin, M.E, Alzari, P.M.
Deposit date:2005-11-22
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of lipid biosynthesis regulation in Gram-positive bacteria.
Embo J., 25, 2006
1MS1
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BU of 1ms1 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MR5
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BU of 1mr5 by Molmil
Orthorhombic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-18
Release date:2003-03-18
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS8
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BU of 1ms8 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS3
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BU of 1ms3 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS4
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BU of 1ms4 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS9
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BU of 1ms9 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose
Descriptor: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme of Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MZ5
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Trypanosoma rangeli sialidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase
Authors:Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M.
Deposit date:2002-10-05
Release date:2002-10-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of sialyltransferase activity in trypanosomal sialidases
Embo J., 19, 2000
1MS5
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BU of 1ms5 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, soaked with N-acetylneuraminyl-a-2,3-thio-galactoside (NA-S-Gal)
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS0
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BU of 1ms0 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)and lactose
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MZ6
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BU of 1mz6 by Molmil
Trypanosoma rangeli sialidase in complex with the inhibitor DANA
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase
Authors:Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M.
Deposit date:2002-10-05
Release date:2002-10-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of sialyltransferase activity in trypanosomal sialidases
Embo J., 19, 2000
2F3X
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BU of 2f3x by Molmil
Crystal structure of FapR (in complex with effector)- a global regulator of fatty acid biosynthesis in B. subtilis
Descriptor: MALONYL-COENZYME A, Transcription factor fapR
Authors:Buschiazzo, A, Guerin, M.E, Alzari, P.M.
Deposit date:2005-11-22
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of lipid biosynthesis regulation in Gram-positive bacteria.
Embo J., 25, 2006

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