1OAS
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![BU of 1oas by Molmil](/molmil-images/mine/1oas) | O-ACETYLSERINE SULFHYDRYLASE FROM SALMONELLA TYPHIMURIUM | Descriptor: | O-ACETYLSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Burkhard, P, Rao, G.S.J, Hohenester, E, Schnackerz, K.D, Cook, P.F, Jansonius, J.N. | Deposit date: | 1999-01-29 | Release date: | 2000-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium. J.Mol.Biol., 283, 1998
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1FCJ
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![BU of 1fcj by Molmil](/molmil-images/mine/1fcj) | CRYSTAL STRUCTURE OF OASS COMPLEXED WITH CHLORIDE AND SULFATE | Descriptor: | CHLORIDE ION, O-ACETYLSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Burkhard, P, Tai, C, Jansonius, J.N, Cook, P.F. | Deposit date: | 2000-07-18 | Release date: | 2000-10-18 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound. J.Mol.Biol., 303, 2000
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1JS6
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![BU of 1js6 by Molmil](/molmil-images/mine/1js6) | Crystal Structure of DOPA decarboxylase | Descriptor: | DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | Deposit date: | 2001-08-16 | Release date: | 2001-10-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nat.Struct.Biol., 8, 2001
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1JS3
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![BU of 1js3 by Molmil](/molmil-images/mine/1js3) | Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa | Descriptor: | CARBIDOPA, DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | Deposit date: | 2001-08-16 | Release date: | 2001-10-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nat.Struct.Biol., 8, 2001
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1HQJ
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![BU of 1hqj by Molmil](/molmil-images/mine/1hqj) | |
1D7M
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![BU of 1d7m by Molmil](/molmil-images/mine/1d7m) | COILED-COIL DIMERIZATION DOMAIN FROM CORTEXILLIN I | Descriptor: | CORTEXILLIN I | Authors: | Burkhard, P, Kammerer, R.A, Steinmetz, M.O, Bourenkov, G.P, Aebi, U. | Deposit date: | 1999-10-19 | Release date: | 2000-03-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges. Structure Fold.Des., 8, 2000
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1D6S
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![BU of 1d6s by Molmil](/molmil-images/mine/1d6s) | CRYSTAL STRUCTURE OF THE K41A MUTANT OF O-ACETYLSERINE SULFHYDRYLASE COMPLEXED IN EXTERNAL ALDIMINE LINKAGE WITH METHIONINE | Descriptor: | METHIONINE, O-ACETYLSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Burkhard, P, Tai, C.H, Ristroph, C.M, Cook, P.F, Jansonius, J.N. | Deposit date: | 1999-10-15 | Release date: | 2000-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium. J.Mol.Biol., 291, 1999
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1KYC
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1D6O
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![BU of 1d6o by Molmil](/molmil-images/mine/1d6o) | NATIVE FKBP | Descriptor: | AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), SULFATE ION | Authors: | Burkhard, P, Taylor, P, Walkinshaw, M.D. | Deposit date: | 1999-10-15 | Release date: | 1999-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
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1D7J
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![BU of 1d7j by Molmil](/molmil-images/mine/1d7j) | FKBP COMPLEXED WITH 4-HYDROXY-2-BUTANONE | Descriptor: | 4-HYDROXY-2-BUTANONE, AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), ... | Authors: | Burkhard, P, Taylor, P, Walkinshaw, M.D. | Deposit date: | 1999-10-18 | Release date: | 1999-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
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1D7I
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![BU of 1d7i by Molmil](/molmil-images/mine/1d7i) | FKBP COMPLEXED WITH METHYL METHYLSULFINYLMETHYL SULFIDE (DSS) | Descriptor: | AMMONIUM ION, METHYL METHYLSULFINYLMETHYL SULFIDE, PROTEIN (FK506-BINDING PROTEIN), ... | Authors: | Burkhard, P, Taylor, P, Walkinshaw, M.D. | Deposit date: | 1999-10-18 | Release date: | 1999-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
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1D7H
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![BU of 1d7h by Molmil](/molmil-images/mine/1d7h) | FKBP COMPLEXED WITH DMSO | Descriptor: | AMMONIUM ION, DIMETHYL SULFOXIDE, PROTEIN (FK506-BINDING PROTEIN), ... | Authors: | Burkhard, P, Taylor, P, Walkinshaw, M.D. | Deposit date: | 1999-10-18 | Release date: | 1999-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
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2XHE
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![BU of 2xhe by Molmil](/molmil-images/mine/2xhe) | Crystal structure of the Unc18-syntaxin 1 complex from Monosiga brevicollis | Descriptor: | SYNTAXIN1, UNC18 | Authors: | Burkhardt, P, Stegmann, C.M, Wahl, M.C, Fasshauer, D. | Deposit date: | 2010-06-14 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Primordial Neurosecretory Apparatus Identified in the Choanoflagellate Monosiga Brevicollis. Proc.Natl.Acad.Sci.USA, 108, 2011
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3G1E
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![BU of 3g1e by Molmil](/molmil-images/mine/3g1e) | X-ray crystal structure of coil 1A of human vimentin | Descriptor: | Vimentin | Authors: | Meier, M, Padilla, G.P, Herrmann, H, Wedig, T, Hergt, M, Patel, T.R, Stetefeld, J, Aebi, U, Burkhard, P. | Deposit date: | 2009-01-29 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J.Mol.Biol., 390, 2009
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1X8Y
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![BU of 1x8y by Molmil](/molmil-images/mine/1x8y) | Human lamin coil 2B | Descriptor: | Lamin A/C | Authors: | Strelkov, S.V, Schumacher, J, Burkhard, P, Aebi, U, Herrmann, H. | Deposit date: | 2004-08-19 | Release date: | 2004-11-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins J.Mol.Biol., 343, 2004
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1GK6
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![BU of 1gk6 by Molmil](/molmil-images/mine/1gk6) | Human vimentin coil 2B fragment linked to GCN4 leucine zipper (Z2B) | Descriptor: | VIMENTIN | Authors: | Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P. | Deposit date: | 2001-08-08 | Release date: | 2002-03-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly. Embo J., 21, 2002
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2XV5
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![BU of 2xv5 by Molmil](/molmil-images/mine/2xv5) | Human lamin A coil 2B fragment | Descriptor: | LAMIN-A/C | Authors: | Kapinos, L.E, Burkhard, P, Aebi, U, Herrmann, H, Strelkov, S.V. | Deposit date: | 2010-10-22 | Release date: | 2011-03-09 | Last modified: | 2019-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Simultaneous Formation of Right- and Left-Handed Anti-Parallel Coiled-Coil Interfaces by a Coil2 Fragment of Human Lamin A. J.Mol.Biol., 408, 2011
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1GK4
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![BU of 1gk4 by Molmil](/molmil-images/mine/1gk4) | HUMAN VIMENTIN COIL 2B FRAGMENT (CYS2) | Descriptor: | ACETATE ION, VIMENTIN | Authors: | Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P. | Deposit date: | 2001-08-08 | Release date: | 2002-03-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly. Embo J., 21, 2002
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1L4X
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![BU of 1l4x by Molmil](/molmil-images/mine/1l4x) | Octameric de novo designed peptide | Descriptor: | CHLORIDE ION, MAGNESIUM ION, SIN-ASP-GLU-LEU-GLU-ARG-ALA-ILE-ARG-GLU-LEU-ALA-ALA-ARG-ILE-LYS-NH2 | Authors: | Meier, M, Lustig, A, Aebi, U, Burkhard, P. | Deposit date: | 2002-03-06 | Release date: | 2002-11-13 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide J.STRUCT.BIOL., 137, 2002
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2JC3
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![BU of 2jc3 by Molmil](/molmil-images/mine/2jc3) | Structure of O-Acetylserine Sulfhydrylase B from Salmonella Typhimurium | Descriptor: | O-ACETYLSERINE SULFHYDRYLASE B, PYRIDOXAL-5'-PHOSPHATE | Authors: | Chattopadhyay, A, Rabeh, W.M, Speroni, F, Meier, M, Ivaninskii, S, Mozzarelli, A, Burkhard, P, Cook, P.F. | Deposit date: | 2006-12-19 | Release date: | 2007-01-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure, Mechanism, and Conformational Dynamics of O-Acetylserine Sulfhydrylase from Salmonella Typhimurium: Comparison of a and B Isozymes. Biochemistry, 46, 2007
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1GK7
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![BU of 1gk7 by Molmil](/molmil-images/mine/1gk7) | HUMAN VIMENTIN COIL 1A FRAGMENT (1A) | Descriptor: | SULFATE ION, VIMENTIN | Authors: | Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P. | Deposit date: | 2001-08-08 | Release date: | 2002-03-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly. Embo J., 21, 2002
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1JBQ
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![BU of 1jbq by Molmil](/molmil-images/mine/1jbq) | STRUCTURE OF HUMAN CYSTATHIONINE BETA-SYNTHASE: A UNIQUE PYRIDOXAL 5'-PHOSPHATE DEPENDENT HEMEPROTEIN | Descriptor: | CYSTATHIONINE BETA-SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Meier, M, Janosik, M, Kery, V, Kraus, J.P, Burkhard, P. | Deposit date: | 2001-06-06 | Release date: | 2001-08-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein. EMBO J., 20, 2001
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1DV8
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![BU of 1dv8 by Molmil](/molmil-images/mine/1dv8) | CRYSTAL STRUCTURE OF THE CARBOHYDRATE RECOGNITION DOMAIN OF THE H1 SUBUNIT OF THE ASIALOGLYCOPROTEIN RECEPTOR | Descriptor: | ASIALOGLYCOPROTEIN RECEPTOR 1, CALCIUM ION, CHLORIDE ION | Authors: | Meier, M, Bider, M.D, Malashkevich, V.N, Spiess, M, Burkhard, P. | Deposit date: | 2000-01-20 | Release date: | 2000-07-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the carbohydrate recognition domain of the H1 subunit of the asialoglycoprotein receptor. J.Mol.Biol., 300, 2000
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3C98
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![BU of 3c98 by Molmil](/molmil-images/mine/3c98) | Revised structure of the munc18a-syntaxin1 complex | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | Authors: | Hattendorf, D.A, Misura, K.M, Burkhardt, P, Scheller, R.H, Fasshauer, D, Weis, W.I. | Deposit date: | 2008-02-15 | Release date: | 2008-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide Embo J., 27, 2008
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4JEU
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![BU of 4jeu by Molmil](/molmil-images/mine/4jeu) | Crystal Structure of Munc18a and Syntaxin1 with native N-terminus complex | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | Authors: | Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I. | Deposit date: | 2013-02-27 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation. Proc.Natl.Acad.Sci.USA, 110, 2013
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