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PDB: 113 件
1GT6
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S146A mutant of Thermomyces (Humicola) lanuginosa lipase complex with oleic acid
分子名称: Lipase, OLEIC ACID
著者Brzozowski, A.M, Yapoudjian, S, Ivanova, M.G, Patkar, S.A, Vind, J, Svendsen, A, Verger, R.
登録日2002-01-11
公開日2003-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Binding of Thermomyces (Humicola) lanuginosa lipase to the mixed micelles of cis-parinaric acid/NaTDC.
Eur.J.Biochem., 269, 2002
1GZY
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BU of 1gzy by Molmil
Human Insulin-like growth factor; In-house data
分子名称: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
著者Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z.
登録日2002-06-10
公開日2002-07-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1ERR
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BU of 1err by Molmil
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE
分子名称: ESTROGEN RECEPTOR, RALOXIFENE
著者Brzozowski, A.M, Pike, A.C.W.
登録日1997-09-08
公開日1998-09-16
最終更新日2013-05-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature, 389, 1997
1GZZ
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Human Insulin-like growth factor; Hamburg data
分子名称: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
著者Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z.
登録日2002-06-10
公開日2002-07-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1E3X
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Native structure of chimaeric amylase from B. amyloliquefaciens and B. licheniformis at 1.92A
分子名称: ALPHA-AMYLASE, CALCIUM ION, SODIUM ION
著者Brzozowski, A.M, Lawson, D.M, Turkenburg, J.P, Bisgaard-Frantzen, H, Svendsen, A, Borchert, T.V, Dauter, Z, Wilson, K.S, Davies, G.J.
登録日2000-06-26
公開日2001-06-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Analysis of a Chimeric Bacterial Alpha-Amylase. High Resolution Analysis of Native and Ligand Complexes
Biochemistry, 39, 2000
1GZR
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Human Insulin-like growth factor; ESRF data
分子名称: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
著者Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z.
登録日2002-05-28
公開日2002-07-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1H02
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BU of 1h02 by Molmil
Human Insulin-like growth factor; SRS Daresbury data
分子名称: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
著者Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z.
登録日2002-06-11
公開日2002-07-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
3W12
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BU of 3w12 by Molmil
Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alpha-CT peptide(704-719) and FAB 83-7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
著者Lawrence, M.C, Smith, B.J, Brzozowsk, A.M.
登録日2012-11-06
公開日2013-01-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4.301 Å)
主引用文献How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
6A3H
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BU of 6a3h by Molmil
2-DEOXY-2-FLURO-B-D-CELLOTRIOSYL/ENZYME INTERMEDIATE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.6 ANGSTROM RESOLUTION
分子名称: ENDOGLUCANASE, GLYCEROL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose
著者Davies, G.J, Varrot, A, Dauter, M, Brzozowski, A.M, Schulein, M, Mackenzie, L, Withers, S.G.
登録日1998-07-22
公開日1999-07-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.
Biochemistry, 37, 1998
1M6C
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BU of 1m6c by Molmil
V68N MYOGLOBIN WITH CO
分子名称: CARBON MONOXIDE, PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE
著者Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J.
登録日1998-08-12
公開日1998-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
1MDN
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WILD TYPE MYOGLOBIN WITH CO
分子名称: PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE
著者Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J.
登録日1998-08-12
公開日1998-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
1M6M
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BU of 1m6m by Molmil
V68N MET MYOGLOBIN
分子名称: PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE
著者Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J.
登録日1998-08-13
公開日1998-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
1MNO
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BU of 1mno by Molmil
V68N MYOGLOBIN OXY FORM
分子名称: OXYGEN MOLECULE, PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE
著者Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J.
登録日1998-08-13
公開日1998-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
4V4F
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BU of 4v4f by Molmil
The structure of the trp RNA-binding attenuation protein (TRAP) bound to a RNA molecule containing UAGAU repeats
分子名称: 5'-R(*UP*AP*GP*AP*UP)-3', TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN
著者Hopcroft, N.H, Manfredo, A, Wendt, A.L, Brzozowski, A.M, Gollnick, P, Antson, A.A.
登録日2003-12-08
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Interaction of RNA with Trap: The Role of Triplet Repeats and Separating Spacer Nucleotides
J.Mol.Biol., 338, 2004
2CC0
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BU of 2cc0 by Molmil
Family 4 carbohydrate esterase from Streptomyces lividans in complex with acetate
分子名称: ACETATE ION, ACETYL-XYLAN ESTERASE, ZINC ION
著者Taylor, E.J, Gloster, T.M, Turkenburg, J.P, Vincent, F, Brzozowski, A.M, Dupont, C, Shareck, F, Centeno, M.S.J, Prates, J.A.M, Puchart, V, Ferreira, L.M.A, Fontes, C.M.G.A, Biely, P, Davies, G.J.
登録日2006-01-10
公開日2006-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Activity of Two Metal-Ion Dependent Acetyl Xylan Esterases Involved in Plant Cell Wall Degradation Reveals a Close Similarity to Peptidoglycan Deacetylases
J.Biol.Chem., 281, 2006
2C71
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The structure of a family 4 acetyl xylan esterase from Clostridium thermocellum in complex with a magnesium ion.
分子名称: GLYCOSIDE HYDROLASE, FAMILY 11:CLOSTRIDIUM CELLULOSOME ENZYME, DOCKERIN TYPE I:POLYSACCHARIDE, ...
著者Taylor, E.J, Turkenburg, P.J, Vincent, F, Brzozowski, A.M, Gloster, T.M, Dupont, C, Shareck, F, Centeno, M.S.J, Prates, J.A.M, Ferreira, L.M.A, Fontes, C.M.G.A, Biely, P, Davies, G.J.
登録日2005-11-17
公開日2006-01-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structure and Activity of Two Metal-Ion Dependent Acetyl Xylan Esterases Involved in Plant Cell-Wall Degradation Reveals a Close Similarity to Peptidoglycan Deacetylases.
J.Biol.Chem., 281, 2006
2C79
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The structure of a family 4 acetyl xylan esterase from Clostridium thermocellum in complex with a colbalt ion.
分子名称: COBALT (II) ION, GLYCOSIDE HYDROLASE, FAMILY 11:CLOSTRIDIUM CELLULOSOME ENZYME, ...
著者Taylor, E.J, Turkenburg, P.J, Vincent, F, Brzozowski, A.M, Gloster, T.M, Dupont, C, Shareck, F, Centeno, M.S.J, Prates, J.A.M, Ferreira, L.M.A, Fontes, C.M.G.A, Biely, P, Davies, G.J.
登録日2005-11-18
公開日2006-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure and Activity of Two Metal-Ion Dependent Acetyl Xylan Esterases Involved in Plant Cell Wall Degradation Reveals a Close Similarity to Peptidoglycan Deacetylases.
J.Biol.Chem., 281, 2006
7A3H
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BU of 7a3h by Molmil
NATIVE ENDOGLUCANASE CEL5A CATALYTIC CORE DOMAIN AT 0.95 ANGSTROMS RESOLUTION
分子名称: ENDOGLUCANASE, ETHANOL, GLYCEROL
著者Davies, G.J, Varrot, A, Dauter, M, Brzozowski, A.M, Schulein, M, Mackenzie, L, Withers, S.G.
登録日1998-08-05
公開日1999-08-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.
Biochemistry, 37, 1998
8CLS
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BU of 8cls by Molmil
Drosophila melanogaster insulin receptor ectodomain in complex with DILP5
分子名称: Insulin-like receptor, Probable insulin-like peptide 5, Probable insulin-like peptide 5 A chain
著者Viola, C.M, Brzozowski, A.M, Shafi, T.
登録日2023-02-17
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans.
Nat Commun, 14, 2023
3A3H
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BU of 3a3h by Molmil
CELLOTRIOSE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHERANS AT 1.6 A RESOLUTION
分子名称: ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Davies, G.J, Brzozowski, A.M, Andersen, K, Schulein, M.
登録日1998-02-01
公開日1999-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.
Biochemistry, 37, 1998
4TGL
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BU of 4tgl by Molmil
CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
分子名称: DIETHYL PHOSPHONATE, TRIACYL-GLYCEROL ACYLHYDROLASE
著者Derewenda, U, Brzozowski, A.M, Lawson, D, Derewenda, Z.S.
登録日1991-07-29
公開日1993-07-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
3TGL
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT
分子名称: TRIACYL-GLYCEROL ACYLHYDROLASE
著者Brady, L, Brzozowski, A.M, Derewenda, Z.S, Dodson, E.J, Dodson, G.G, Tolley, S.P, Turkenburg, J.P, Christiansen, L, Huge-Jensen, B, Norskov, L, Thim, L.
登録日1991-07-29
公開日1993-07-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
5A3H
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BU of 5a3h by Molmil
2-DEOXY-2-FLURO-B-D-CELLOBIOSYL/ENZYME INTERMEDIATE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.8 ANGSTROMS RESOLUTION
分子名称: ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose
著者Davies, G.J, Varrot, A, Dauter, M, Brzozowski, A.M, Schulein, M, Mackenzie, L, Withers, S.G.
登録日1998-07-23
公開日1999-07-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.
Biochemistry, 37, 1998
7TAA
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BU of 7taa by Molmil
FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE
分子名称: CALCIUM ION, MODIFIED ACARBOSE HEXASACCHARIDE, TAKA AMYLASE
著者Davies, G.J, Brzozowski, A.M.
登録日1997-10-06
公開日1998-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 A resolution.
Biochemistry, 36, 1997
1QKM
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HUMAN OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PARTIAL AGONIST GENISTEIN
分子名称: ESTROGEN RECEPTOR BETA, GENISTEIN
著者Pike, A.C.W, Brzozowski, A.M, Carlquist, M.
登録日1999-07-27
公開日2000-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist
Embo J., 18, 1999

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