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PDB: 148 件

1Z9O
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1.9 Angstrom Crystal Structure of the Rat VAP-A MSP Homology Domain in Complex with the Rat ORP1 FFAT Motif
分子名称: Oxysterol binding protein, Vesicle-associated membrane protein-associated protein A
著者Kaiser, S.E, Brickner, J.H, Reilein, A.R, Fenn, T.D, Walter, P, Brunger, A.T.
登録日2005-04-03
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of FFAT motif-mediated ER targeting
Structure, 13, 2005
1Z9L
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1.7 Angstrom Crystal Structure of the Rat VAP-A MSP Homology Domain
分子名称: Vesicle-associated membrane protein-associated protein A
著者Kaiser, S.E, Brickner, J.H, Reilein, A.R, Fenn, T.D, Walter, P, Brunger, A.T.
登録日2005-04-03
公開日2005-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of FFAT motif-mediated ER targeting
Structure, 13, 2005
1SFC
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NEURONAL SYNAPTIC FUSION COMPLEX
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PROTEIN (SNAP-25B), PROTEIN (SYNAPTOBREVIN 2), ...
著者Sutton, R.B, Brunger, A.T.
登録日1998-08-24
公開日1998-10-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution.
Nature, 395, 1998
1G17
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CRYSTAL STRUCTURE OF SEC4-GUANOSINE-5'-(BETA,GAMMA)-IMIDOTRIPHOSPHATE
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAS-RELATED PROTEIN SEC4
著者Stroupe, C, Brunger, A.T.
登録日2000-10-10
公開日2000-12-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1G16
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CRYSTAL STRUCTURE OF SEC4-GDP
分子名称: COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, RAS-RELATED PROTEIN SEC4
著者Stroupe, C, Brunger, A.T.
登録日2000-10-10
公開日2000-12-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1JXM
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CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANIDINE, GUANOSINE-5'-MONOPHOSPHATE, ...
著者Tavares, G.A, Panepucci, E.H, Brunger, A.T.
登録日2001-09-07
公開日2002-01-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
9BRZ
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V0-only V-ATPase and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-12
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRY
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V0-only V-ATPase in synaptophysin gene knock-out mouse brain isolated synaptic vesicles
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-12
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
1YTT
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BU of 1ytt by Molmil
YB SUBSTITUTED SUBTILISIN FRAGMENT OF MANNOSE BINDING PROTEIN-A (SUB-MBP-A), MAD STRUCTURE AT 110K
分子名称: MANNOSE-BINDING PROTEIN A, YTTERBIUM (III) ION
著者Burling, F.T, Weis, W.I, Flaherty, K.M, Brunger, A.T.
登録日1995-11-09
公開日1996-06-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Direct observation of protein solvation and discrete disorder with experimental crystallographic phases.
Science, 271, 1996
6GL8
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Crystal structure of Bcl-2 in complex with the novel orally active inhibitor S55746
分子名称: Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2, ~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide
著者Casara, P, Davidson, J, Claperon, A, Le Toumelin-Braizat, G, Vogler, M, Bruno, A, Chanrion, M, Lysiak-Auvity, G, Le Diguarher, T, Starck, J.B, Chen, I, Whitehead, N, Graham, C, Matassova, N, Dokurno, P, Pedder, C, Wang, Y, Qiu, S, Girard, A.M, Schneider, E, Grave, F, Studeny, A, Guasconi, G, Rocchetti, F, Maiga, S, Henlin, J.M, Colland, F, Kraus-Berthier, L, Le Gouill, S, Dyer, M.J.S, Hubbard, R, Wood, M, Amiot, M, Cohen, G.M, Hickman, J.A, Morris, E, Murray, J, Geneste, O.
登録日2018-05-23
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Oncotarget, 9, 2018
9BRU
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Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRT
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Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRA
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Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRR
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BU of 9brr by Molmil
Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRS
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BU of 9brs by Molmil
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRQ
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BU of 9brq by Molmil
Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
5FOZ
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BU of 5foz by Molmil
De novo structure of the binary mosquito larvicide BinAB at pH 10
分子名称: LARVICIDAL TOXIN PROTEIN, SODIUM ION, TOXIN
著者Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S.
登録日2015-11-26
公開日2016-10-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.
Nature, 539, 2016
5G37
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MR structure of the binary mosquito larvicide BinAB at pH 5
分子名称: 41.9 KDA INSECTICIDAL TOXIN, LARVICIDAL TOXIN 51 KDA PROTEIN
著者Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S.
登録日2016-04-24
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.
Nature, 539, 2016
7RZS
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BU of 7rzs by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with L938F mutation
分子名称: SARS-CoV-2 HR1 L938F linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZR
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Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with D936Y mutation
分子名称: SARS-CoV-2 HR1 D936Y linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.27 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZT
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Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with S940F mutation
分子名称: SARS-CoV-2 HR1 S940F linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.35 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZU
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Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with A942S mutation
分子名称: SARS-CoV-2 HR1 A942S linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZQ
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BU of 7rzq by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex
分子名称: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.09 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZV
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Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation
分子名称: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2021-08-27
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
1FZM
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MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日2000-10-03
公開日2001-03-28
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001

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