1BOW
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![BU of 1bow by Molmil](/molmil-images/mine/1bow) | MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR (APO FORM) | Descriptor: | MANGANESE (II) ION, MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR | Authors: | Zheleznova, E.E, Markham, P.N, Neyfakh, A.A, Brennan, R.G. | Deposit date: | 1998-08-06 | Release date: | 1999-08-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Cell(Cambridge,Mass.), 96, 1999
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2BOW
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![BU of 2bow by Molmil](/molmil-images/mine/2bow) | MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR IN COMPLEX WITH A LIGAND, TETRAPHENYLPHOSPHONIUM | Descriptor: | MANGANESE (II) ION, MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR, SULFATE ION, ... | Authors: | Zheleznova, E.E, Markham, P.N, Neyfakh, A.A, Brennan, R.G. | Deposit date: | 1998-08-06 | Release date: | 1999-08-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Cell(Cambridge,Mass.), 96, 1999
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3RJP
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![BU of 3rjp by Molmil](/molmil-images/mine/3rjp) | |
2BSQ
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![BU of 2bsq by Molmil](/molmil-images/mine/2bsq) | FitAB bound to DNA | Descriptor: | IR36, FORWARD STRAND, REVERSE STRAND, ... | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | Deposit date: | 2005-05-23 | Release date: | 2006-08-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Fitab from Neisseria Gonorrhoeae Bound to DNA Reveals a Tetramer of Toxin-Antitoxin Heterodimers Containing Pin Domains and Ribbon-Helix-Helix Motifs. J.Biol.Chem., 281, 2006
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3T03
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![BU of 3t03 by Molmil](/molmil-images/mine/3t03) | Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16 | Descriptor: | (5Z)-5-(5-bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | Authors: | Rajagopalan, S, Webb, P, Baxter, J.D, Brennan, R.G, Phillips, K.J. | Deposit date: | 2011-07-19 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | GQ-16, a novel peroxisome proliferator-activated receptor (PPAR gamma) ligand, promotes insulin sensitization without weight gain. J.Biol.Chem., 287, 2012
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3TPE
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![BU of 3tpe by Molmil](/molmil-images/mine/3tpe) | The phipa p3121 structure | Descriptor: | Serine/threonine-protein kinase HipA | Authors: | Schumacher, M.A, Link, T, Brennan, R.G. | Deposit date: | 2011-09-07 | Release date: | 2012-10-03 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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3TPD
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![BU of 3tpd by Molmil](/molmil-images/mine/3tpd) | Structure of pHipA, monoclinic form | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Serine/threonine-protein kinase HipA | Authors: | schumacher, M.A, link, T, Brennan, R.G. | Deposit date: | 2011-09-07 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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2EV0
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![BU of 2ev0 by Molmil](/molmil-images/mine/2ev0) | Bacillus subtilis manganese transport regulator (MNTR) bound to cadmium | Descriptor: | CADMIUM ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-30 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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2DTZ
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![BU of 2dtz by Molmil](/molmil-images/mine/2dtz) | |
3BT9
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![BU of 3bt9 by Molmil](/molmil-images/mine/3bt9) | |
2EV5
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![BU of 2ev5 by Molmil](/molmil-images/mine/2ev5) | Bacillus subtilis manganese transport regulator (MNTR) bound to calcium | Descriptor: | CALCIUM ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-31 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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3BTI
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![BU of 3bti by Molmil](/molmil-images/mine/3bti) | |
3TPT
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![BU of 3tpt by Molmil](/molmil-images/mine/3tpt) | Structure of HipA(D309Q) bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | schumacher, M.A, link, T, Brennan, R.G. | Deposit date: | 2011-09-08 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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2EV6
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![BU of 2ev6 by Molmil](/molmil-images/mine/2ev6) | Bacillus subtilis manganese transport regulator (MNTR) bound to zinc | Descriptor: | CITRATE ANION, GLYCEROL, Transcriptional regulator mntR, ... | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-31 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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2F5E
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![BU of 2f5e by Molmil](/molmil-images/mine/2f5e) | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AB conformation, pH 6.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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3BTC
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![BU of 3btc by Molmil](/molmil-images/mine/3btc) | |
3BTJ
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![BU of 3btj by Molmil](/molmil-images/mine/3btj) | |
3BTL
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![BU of 3btl by Molmil](/molmil-images/mine/3btl) | |
2F5F
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![BU of 2f5f by Molmil](/molmil-images/mine/2f5f) | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 8.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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3TPV
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![BU of 3tpv by Molmil](/molmil-images/mine/3tpv) | Structure of pHipA bound to ADP | Descriptor: | ADENINE, SULFATE ION, Serine/threonine-protein kinase HipA | Authors: | Schumacher, M.A, Link, T.M, Brennan, R.G. | Deposit date: | 2011-09-08 | Release date: | 2012-10-03 | Last modified: | 2012-10-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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2F5C
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![BU of 2f5c by Molmil](/molmil-images/mine/2f5c) | Bacillus subtilis Manganese transport regulator (MNTR) bound to manganese, hexagonal crystal form | Descriptor: | MANGANESE (II) ION, SULFATE ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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2F5D
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![BU of 2f5d by Molmil](/molmil-images/mine/2f5d) | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 6.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
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5HVO
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![BU of 5hvo by Molmil](/molmil-images/mine/5hvo) | Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A | Descriptor: | (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE | Authors: | Miao, Y, Brennan, R.G. | Deposit date: | 2016-01-28 | Release date: | 2017-05-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.467 Å) | Cite: | Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design. MBio, 8, 2017
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5HK0
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![BU of 5hk0 by Molmil](/molmil-images/mine/5hk0) | |
5HUS
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![BU of 5hus by Molmil](/molmil-images/mine/5hus) | |