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PDB: 157 件
4OAY
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BldD CTD-c-di-GMP complex
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G.
登録日2014-01-06
公開日2014-11-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014
4OAZ
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BldD CTD-c-di-GMP complex
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative DNA-binding protein
著者Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G.
登録日2014-01-06
公開日2014-11-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014
4NL3
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Crystal Structure of Listeria monocytogenes Hfq in complex with U6 RNA
分子名称: 5'-R(*UP*UP*UP*UP*UP*U)-3', Protein hfq
著者Kovach, A.R, Brennan, R.G.
登録日2013-11-13
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
Rna, 20, 2014
4PUR
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Crystal structure of MglA from Francisella tularensis
分子名称: D-MALATE, Macrophage growth locus, subunit A
著者Cuthbert, B.J, Schumacher, M.A, Brennan, R.G.
登録日2014-03-13
公開日2015-06-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA).
Plos One, 10, 2015
4NOY
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Crystal structure of Listeria monocytogenes Hfq F43W
分子名称: Protein Hfq, S-1,2-PROPANEDIOL
著者Canty, J.T, Kovach, A.R, Brennan, R.G.
登録日2013-11-20
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
Rna, 20, 2014
5DXN
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Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2
分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXI
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Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ...
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXF
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Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain
分子名称: trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.563 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXL
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Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 1
分子名称: trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.573 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DX9
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Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans
分子名称: 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXO
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Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3
分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F6F
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S. aureus MepR G34R Mutant
分子名称: MarR family regulatory protein
著者Newman, C.E, Birukou, I, Brennan, R.G.
登録日2015-12-05
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献S. aureus MepR G34R Mutant
To Be Published
1JFS
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
分子名称: 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR
著者Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
登録日2001-06-21
公開日2002-02-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JFT
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
分子名称: 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ...
著者Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
登録日2001-06-21
公開日2002-02-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JBG
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Crystal Structure of MtaN, the Bacillus subtilis Multidrug Transporter Activator, N-terminus
分子名称: transcription activator of multidrug-efflux transporter genes mta
著者Godsey, M.H, Neyfakh, A.A, Brennan, R.G.
登録日2001-06-04
公開日2001-11-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of MtaN, a global multidrug transporter gene activator.
J.Biol.Chem., 276, 2001
1JLS
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STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE URACIL/CPR 2 MUTANT C128V
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PHOSPHATE ION, ...
著者Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ullman, B, Brennan, R.G.
登録日2001-07-16
公開日2002-01-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JT0
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Crystal structure of a cooperative QacR-DNA complex
分子名称: HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, QACA operator, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-20
公開日2002-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
EMBO J., 21, 2002
1JTX
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Crystal structure of the multidrug binding transcriptional regulator QacR bound to crystal violet
分子名称: CRYSTAL VIOLET, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-22
公開日2001-12-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JUS
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Crystal structure of the multidrug binding transcriptional repressor QacR bound to rhodamine 6G
分子名称: HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, RHODAMINE 6G, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-27
公開日2001-12-12
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JTY
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Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium
分子名称: ETHIDIUM, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-22
公開日2001-12-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JUM
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Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine
分子名称: BERBERINE, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-24
公開日2001-12-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1KQ1
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1.55 A Crystal structure of the pleiotropic translational regulator, Hfq
分子名称: ACETIC ACID, Host Factor for Q beta
著者Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G.
登録日2002-01-03
公開日2002-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
1KQ2
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Crystal Structure of an Hfq-RNA Complex
分子名称: 5'-R(*AP*UP*UP*UP*UP*UP*G)-3', Host factor for Q beta
著者Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G.
登録日2002-01-03
公開日2002-07-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
1LIJ
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STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP
分子名称: 2-RIBOFURANOSYL-3-IODO-2,3-DIHYDRO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, CHLORIDE ION, MAGNESIUM ION, ...
著者Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G.
登録日2002-04-17
公開日2002-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
1LIK
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STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE
分子名称: ADENOSINE, CHLORIDE ION, SULFATE ION, ...
著者Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G.
登録日2002-04-17
公開日2002-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000

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