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PDB: 123 件

1CHJ
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STRUCTURAL STUDIES OF THE ROLES OF RESIDUES 82 AND 85 AT THE INTERACTIVE FACE OF CYTOCHROME C
分子名称: CYTOCHROME C, HEME C, SULFATE ION
著者Lo, T.P, Brayer, G.D.
登録日1994-06-01
公開日1994-12-20
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of the roles of residues 82 and 85 at the interactive face of cytochrome c.
Biochemistry, 34, 1995
1CTY
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MUTATION OF TYROSINE-67 IN CYTOCHROME C SIGNIFICANTLY ALTERS THE LOCAL HEME ENVIRONMENT
分子名称: CYTOCHROME C, HEME C, SULFATE ION
著者Berghuis, A.M, Brayer, G.D.
登録日1993-02-15
公開日1993-07-15
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mutation of tyrosine-67 to phenylalanine in cytochrome c significantly alters the local heme environment.
J.Mol.Biol., 235, 1994
1HV1
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DISSECTING ELECTROSTATIC INTERACTIONS AND THE PH-DEPENDENT ACTIVITY OF A FAMILY 11 GLYCOSIDASE
分子名称: ENDO-1,4-BETA-XYLANASE
著者Joshi, M.D, Sidhu, G, Nielsen, J.E, Brayer, G.D, Withers, S.G, McIntosh, L.P.
登録日2001-01-05
公開日2001-09-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
Biochemistry, 40, 2001
1CHH
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STRUCTURAL STUDIES OF THE ROLES OF RESIDUES 82 AND 85 AT THE INTERACTIVE FACE OF CYTOCHROME C
分子名称: CYTOCHROME C, HEME C, SULFATE ION
著者Lo, T.P, Brayer, G.D.
登録日1994-06-01
公開日1994-12-20
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural studies of the roles of residues 82 and 85 at the interactive face of cytochrome c.
Biochemistry, 34, 1995
1YTC
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BU of 1ytc by Molmil
THERMODYNAMIC CYCLES AS PROBES OF STRUCTURE-FUNCTION RELATIONSHIPS IN UNFOLDED PROTEINS
分子名称: HEME C, SULFATE ION, YEAST ISO-2 CYTOCHROME C
著者Luo, Y, Brayer, G.D.
登録日1995-07-03
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamic cycles as probes of structure in unfolded proteins.
Biochemistry, 35, 1996
1YMB
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BU of 1ymb by Molmil
HIGH RESOLUTION STUDY OF THE THREE-DIMENSIONAL STRUCTURE OF HORSE HEART METMYOGLOBIN
分子名称: METMYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Evans, S.V, Brayer, G.D.
登録日1993-09-27
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution study of the three-dimensional structure of horse heart metmyoglobin.
J.Mol.Biol., 213, 1990
3BAX
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BU of 3bax by Molmil
N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Azide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
著者Maurus, R, Brayer, G.D.
登録日2007-11-08
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAW
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Human pancreatic alpha-amylase complexed with azide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
著者Maurus, R, Brayer, G.D.
登録日2007-11-08
公開日2008-03-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAK
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N298S mutant of Human Pancreatic Alpha-Amylase in complex with nitrate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
著者Fredriksen, J.R, Maurus, R, Brayer, G.D.
登録日2007-11-08
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAY
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N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
著者Fredriksen, J.R, Maurus, R, Brayer, G.D.
登録日2007-11-08
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAJ
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Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
著者Fredriksen, J.R, Maurus, R, Brayer, G.D.
登録日2007-11-07
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAI
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Human Pancreatic Alpha Amylase with Bound Nitrate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
著者Fredriksen, J.R, Maurus, R, Brayer, G.D.
登録日2007-11-07
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
1SGC
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BU of 1sgc by Molmil
THE 1.8 ANGSTROMS STRUCTURE OF THE COMPLEX BETWEEN CHYMOSTATIN AND STREPTOMYCES GRISEUS PROTEASE A. A MODEL FOR SERINE PROTEASE CATALYTIC TETRAHEDRAL INTERMEDIATES
分子名称: CHYMOSTATIN A, PROTEINASE A
著者Delbaere, L.T.J, Brayer, G.D.
登録日1986-04-18
公開日1986-07-14
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates.
J.Mol.Biol., 183, 1985
5TUN
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BU of 5tun by Molmil
Crystal structure of uninhibited human Cathepsin K at 1.62 Angstrom resolution
分子名称: Cathepsin K
著者Aguda, A.H, Kruglyak, N, Nguyen, N.T, Law, S, Bromme, D, Brayer, G.D.
登録日2016-11-06
公開日2017-01-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib.
Biochem. J., 474, 2017
1U30
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In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing maltosyl-alpha (1,4)-D-gluconhydroximo-1,5-lactam
分子名称: (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ...
著者Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2004-07-20
公開日2004-09-07
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors.
J.Biol.Chem., 279, 2004
1KB3
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Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ...
著者Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2001-11-05
公開日2002-05-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
5U3A
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Ultra High Resolution Crystal Structure of Human Pancreatic Alpha Amylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Caner, S, Brayer, G.D.
登録日2016-12-01
公開日2017-12-06
最終更新日2022-04-27
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic alpha-Amylase.
Acs Chem.Biol., 14, 2019
1U33
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In situ extension as an approach for identifying novel alpha-amylase inhibitors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4'-O-METHYL-MALTOSYL-ALPHA (1,4)-(Z, 3S,4S,5R,6R)-3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-PIPERIDIN-2-ONE, ...
著者Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2004-07-20
公開日2004-09-07
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors.
J.Biol.Chem., 279, 2004
1HRC
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HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF HORSE HEART CYTOCHROME C
分子名称: CYTOCHROME C, HEME C
著者Luo, Y, Brayer, G.D.
登録日1994-08-16
公開日1994-11-01
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution three-dimensional structure of horse heart cytochrome c.
J.Mol.Biol., 214, 1990
1U2Y
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In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam
分子名称: (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ...
著者Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2004-07-20
公開日2004-09-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors.
J.Biol.Chem., 279, 2004
1RAP
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THE STRUCTURE AND FUNCTION OF OMEGA LOOP A REPLACEMENTS IN CYTOCHROME C
分子名称: PROTOPORPHYRIN IX CONTAINING FE, REP A2 ISO-1-CYTOCHROME C, SULFATE ION
著者Murphy, M.E.P, Brayer, G.D.
登録日1992-08-25
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure and function of omega loop A replacements in cytochrome c.
Protein Sci., 2, 1993
1YEA
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STRUCTURE DETERMINATION AND ANALYSIS OF YEAST ISO-2-CYTOCHROME C AND A COMPOSITE MUTANT PROTEIN
分子名称: CYTOCHROME C, HEME C, SULFATE ION
著者Murphy, M.E.P, Brayer, G.D.
登録日1991-10-29
公開日1993-10-31
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination and analysis of yeast iso-2-cytochrome c and a composite mutant protein.
J.Mol.Biol., 227, 1992
1XCX
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Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-6)-beta-D-glucopyranose, Alpha-amylase, ...
著者Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D.
登録日2004-09-03
公開日2004-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005
1XCW
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Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-amylase, ...
著者Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D.
登録日2004-09-03
公開日2004-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005
1XD0
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Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, Alpha-amylase, ...
著者Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D.
登録日2004-09-03
公開日2004-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005

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