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PDB: 11 件

3IAE
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BU of 3iae by Molmil
Structure of benzaldehyde lyase A28S mutant with benzoylphosphonate
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION
著者Brandt, G.S, Petsko, G.A, Ringe, D, McLeish, M.J.
登録日2009-07-13
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition.
J.Am.Chem.Soc., 132, 2010
3IAF
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BU of 3iaf by Molmil
Structure of benzaldehyde lyase A28S mutant with monomethyl benzoylphosphonate
分子名称: Benzaldehyde lyase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Brandt, G.S, Petsko, G.A, Ringe, D, McLeish, M.J.
登録日2009-07-13
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition.
J.Am.Chem.Soc., 132, 2010
3D7K
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BU of 3d7k by Molmil
Crystal structure of benzaldehyde lyase in complex with the inhibitor MBP
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION
著者Brandt, G.S.
登録日2008-05-21
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester
Biochemistry, 47, 2008
3F6E
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BU of 3f6e by Molmil
Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION
著者Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F.
登録日2008-11-05
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Biochemistry, 48, 2009
3F6B
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BU of 3f6b by Molmil
Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor PAA
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION
著者Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F.
登録日2008-11-05
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Biochemistry, 48, 2009
3FSJ
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BU of 3fsj by Molmil
Crystal structure of benzoylformate decarboxylase in complex with the inhibitor MBP
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, CALCIUM ION
著者Brandt, G.S, Kenyon, G.L, McLeish, M.J, Jordan, F, Petsko, G.A, Ringe, D.
登録日2009-01-09
公開日2009-01-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor.
Biochemistry, 48, 2009
6DSS
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BU of 6dss by Molmil
Re-refinement of P. falciparum orotidine 5'-monophosphate decarboxylase
分子名称: Orotidine 5'-monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
著者Brandt, G.S, Novak, W.R.P.
登録日2018-06-14
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase provides a clearer picture of an important malarial drug target.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6DSQ
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BU of 6dsq by Molmil
Re-refinement of P. falciparum orotidine 5'-monophosphate decarboxylase
分子名称: Orotidine 5'-monophosphate decarboxylase
著者Brandt, G.S, Novak, W.R.P.
登録日2018-06-14
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase provides a clearer picture of an important malarial drug target.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6DSR
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BU of 6dsr by Molmil
Re-refinement of P. falciparum orotidine 5'-monophosphate decarboxylase
分子名称: Orotidine 5'-monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
著者Brandt, G.S, Novak, W.R.P.
登録日2018-06-14
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase provides a clearer picture of an important malarial drug target.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6PX2
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BU of 6px2 by Molmil
Acropora millepora GAPDH
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
著者Brandt, G.S, Fields, P.A.
登録日2019-07-24
公開日2019-12-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Thermal stability and structure of glyceraldehyde-3-phosphate dehydrogenase from the coral Acropora millepora.
Rsc Adv, 11, 2021
5T1J
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BU of 5t1j by Molmil
Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet
分子名称: DNA, T-box transcription factor TBX21
著者Liu, C.F, Brandt, G.S, Hoang, Q, Hwang, E.S, Naumova, N, Lazarevic, V, Dekker, J, Glimcher, L.H, Ringe, D, Petsko, G.A.
登録日2016-08-19
公開日2016-10-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.947 Å)
主引用文献Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.
Proc.Natl.Acad.Sci.USA, 113, 2016

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件を2024-06-12に公開中

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