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PDB: 19 件

6EZC
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Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
6EI8
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BU of 6ei8 by Molmil
Crystal structure of human tRNA-dihydrouridine (20) synthase dsRBD F359A mutant
分子名称: SULFATE ION, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2017-09-18
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand.
Biochemistry, 58, 2019
4WFS
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BU of 4wfs by Molmil
Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ...
著者Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D.
登録日2014-09-17
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res., 43, 2015
4WFT
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BU of 4wft by Molmil
Crystal structure of tRNA-dihydrouridine(20) synthase dsRBD domain
分子名称: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D.
登録日2014-09-17
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res., 43, 2015
7TQB
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BU of 7tqb by Molmil
Crystal structure of monoclonal S9.6 Fab bound to DNA-RNA hybrid
分子名称: DNA, FAB S9.6 Heavy Chain, FAB S9.6 Light Chain, ...
著者Bou-Nader, C, Zhang, J.
登録日2022-01-26
公開日2022-03-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of R-loop recognition by the S9.6 monoclonal antibody.
Nat Commun, 13, 2022
6EI9
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BU of 6ei9 by Molmil
Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Bou-Nader, C, Hamdane, D.
登録日2017-09-18
公開日2018-01-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario.
Nucleic Acids Res., 46, 2018
6EZB
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BU of 6ezb by Molmil
Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ...
著者Bou-Nader, C, Bregeon, D, Pecqueur, L, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
6EZA
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BU of 6eza by Molmil
Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
7TQA
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BU of 7tqa by Molmil
Crystal Structure of monoclonal S9.6 Fab
分子名称: Fab S9.6 heavy chain, Fab S9.6 light chain, GLYCEROL, ...
著者Bou-Nader, C, Zhang, J.
登録日2022-01-26
公開日2022-03-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.328 Å)
主引用文献Structural basis of R-loop recognition by the S9.6 monoclonal antibody.
Nat Commun, 13, 2022
9C9R
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BU of 9c9r by Molmil
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain, F1090C/G1326S variant
分子名称: non-specific serine/threonine protein kinase
著者Bou-Nader, C, Bahmanjah, S, Zhang, J.
登録日2024-06-14
公開日2024-08-21
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
9C9Q
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BU of 9c9q by Molmil
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain
分子名称: non-specific serine/threonine protein kinase
著者Bou-Nader, C, Bahmanjah, S, Zhang, J.
登録日2024-06-14
公開日2024-08-21
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
7MRL
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BU of 7mrl by Molmil
Structure of HIV-1 matrix domain bound to human tRNALys3
分子名称: HIV-1 matrix domain, MAGNESIUM ION, tRNA Lys3
著者Bou-Nader, C, Zhang, J.
登録日2021-05-07
公開日2021-08-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization.
Cell Host Microbe, 29, 2021
7NDZ
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BU of 7ndz by Molmil
ThyX reconstituted with N5-carbinolamine flavin
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ...
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2021-02-02
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An enzymatic activation of formaldehyde for nucleotide methylation.
Nat Commun, 12, 2021
7NDW
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BU of 7ndw by Molmil
ThyX-FADH2 soaked with 20 mM Formaldehyde
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ...
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2021-02-02
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An enzymatic activation of formaldehyde for nucleotide methylation.
Nat Commun, 12, 2021
5OC5
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BU of 5oc5 by Molmil
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD K419A-K420A mutant
分子名称: CHLORIDE ION, GLYCEROL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-nader, C, Pecqueur, L, Hamdane, D.
登録日2017-06-29
公開日2018-12-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Nucleic Acids Res., 47, 2019
5NL1
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BU of 5nl1 by Molmil
Shigella IpaA-VBS3/TBS in complex with the Talin VBS1 domain 488-512
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Invasin IpaA, ...
著者Bou-Nader, C, Pecqueur, L, Valencia-Gallardo, C, Fontecave, M, Tran Van Nhieu, G.
登録日2017-04-03
公開日2018-05-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
Cell Rep, 26, 2019
5OC4
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BU of 5oc4 by Molmil
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant
分子名称: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ...
著者Bou-nader, C, Pecqueur, L, Hamdane, D.
登録日2017-06-29
公開日2018-12-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Nucleic Acids Res., 47, 2019
5OC6
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BU of 5oc6 by Molmil
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD in complex with a 22 nucleotide dsRNA
分子名称: RNA, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-nader, C, Pecqueur, L, Hamdane, D.
登録日2017-06-29
公開日2018-12-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Nucleic Acids Res., 47, 2019
6OL3
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BU of 6ol3 by Molmil
Crystal structure of an adenovirus virus-associated RNA
分子名称: Adenovirus Virus-Associated (VA) RNA I apical and central domains, POTASSIUM ION
著者Hood, I.V, Gordon, J.M, Bou-Nader, C, Henderson, F.V, Bahmanjah, S, Zhang, J.
登録日2019-04-15
公開日2019-07-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Crystal structure of an adenovirus virus-associated RNA.
Nat Commun, 10, 2019

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件を2024-11-06に公開中

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