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PDB: 6 件

5IT5
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Thermus thermophilus PilB core ATPase region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP binding motif-containing protein PilF, MAGNESIUM ION, ...
著者Mancl, J, Robinson, H, Black, W, Yang, Z, Schubot, F.
登録日2016-03-16
公開日2016-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.648 Å)
主引用文献Crystal Structure of a Type IV Pilus Assembly ATPase: Insights into the Molecular Mechanism of PilB from Thermus thermophilus.
Structure, 24, 2016
8BN8
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METTL3-METTL14 heterodimer bound to the SAM competitive small molecule inhibitor STM3006
分子名称: 2-[[4-(6-bromanyl-2~{H}-indazol-4-yl)-1,2,3-triazol-1-yl]methyl]-6-[(4,4-dimethylpiperidin-1-yl)methyl]imidazo[1,2-a]pyridine, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit
著者Pilka, E.S, Thomas, B, Blackaby, W, Hardick, D, Feeney, K, Ridgill, M, Rotty, B, Rausch, O.
登録日2022-11-13
公開日2023-09-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.213 Å)
主引用文献Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Cancer Discov, 13, 2023
4A7J
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Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance
分子名称: HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5
著者Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E.
登録日2011-11-14
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance
Nat.Struct.Mol.Biol., 19, 2012
7O2I
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METTL3-METTL14 heterodimer bound to the SAM competitive small molecule inhibitor STM2457
分子名称: DIMETHYL SULFOXIDE, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, ...
著者Pilka, E.S, Blackaby, W, Hardick, D, Harper, C, Hewstone, D, Ridgill, M, Rotty, B, Rausch, O.
登録日2021-03-30
公開日2021-04-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Nature, 593, 2021
1SGL
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The three-dimensional structure and X-ray sequence reveal that trichomaglin is a novel S-like ribonuclease
分子名称: SULFATE ION, trichomaglin
著者Gan, J.-H, Yu, L, Wu, J, Xu, H, Choudhary, J.S, Blackstock, W.P, Liu, W.-Y, Xia, Z.-X.
登録日2004-02-24
公開日2004-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The three-dimensional structure and X-ray sequence reveal that trichomaglin is a novel S-like ribonuclease.
Structure, 12, 2004
7TZL
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The DH dehydratase domain of AlnB
分子名称: 3-oxoacyl-[acyl-carrier-protein] reductase
著者Swain, K, Blackson, W, Wang, B, Zhao, H, Nannenga, B.L.
登録日2022-02-16
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The programming of alpha,beta-polyene biosynthesis by a bacterial iterative type I polyketide synthase
To Be Published

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件を2024-10-09に公開中

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