353D
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![BU of 353d by Molmil](/molmil-images/mine/353d) | CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE | Descriptor: | RNA (5'-R(*AP*UP*CP*CP*CP*CP*CP*GP*UP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*CP*GP*GP*GP*GP*GP*AP*U)-3') | Authors: | Betzel, C, Lorenz, S, Furste, J.P, Bald, R, Zhang, M, Schneider, T.R, Wilson, K.S, Erdmann, V.A. | Deposit date: | 1997-09-29 | Release date: | 1997-11-10 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure. FEBS Lett., 351, 1994
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2CTX
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![BU of 2ctx by Molmil](/molmil-images/mine/2ctx) | THE REFINED CRYSTAL STRUCTURE OF ALPHA-COBRATOXIN FROM NAJA NAJA SIAMENSIS AT 2.4-ANGSTROMS RESOLUTION | Descriptor: | ALPHA-COBRATOXIN | Authors: | Betzel, C, Lange, G, Pal, G.P, Wilson, K.S, Maelicke, A, Saenger, W. | Deposit date: | 1991-09-24 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution. J.Biol.Chem., 266, 1991
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2PRK
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1PEK
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![BU of 1pek by Molmil](/molmil-images/mine/1pek) | STRUCTURE OF THE COMPLEX OF PROTEINASE K WITH A SUBSTRATE-ANALOGUE HEXA-PEPTIDE INHIBITOR AT 2.2 ANGSTROMS RESOLUTION | Descriptor: | D-DAL-ALA-NH2, PEPTIDE PRO-ALA-PRO-PHE, PROTEINASE K | Authors: | Betzel, C, Singh, T.P, Visanji, M, Peters, K, Fittkau, S, Saenger, W, Wilson, K.S. | Deposit date: | 1993-01-19 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution. J.Biol.Chem., 268, 1993
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1IC6
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![BU of 1ic6 by Molmil](/molmil-images/mine/1ic6) | STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION | Descriptor: | CALCIUM ION, NITRATE ION, PROTEINASE K | Authors: | Betzel, C, Gourinath, S, Kumar, P, Kaur, P, Perbandt, M, Eschenburg, S, Singh, T.P. | Deposit date: | 2001-03-30 | Release date: | 2001-04-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution. Biochemistry, 40, 2001
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1SVN
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![BU of 1svn by Molmil](/molmil-images/mine/1svn) | SAVINASE | Descriptor: | CALCIUM ION, SAVINASE (TM) | Authors: | Betzel, C, Klupsch, S, Papendorf, G, Hastrup, S, Branner, S, Wilson, K.S. | Deposit date: | 1995-09-01 | Release date: | 1996-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 A resolution. J.Mol.Biol., 223, 1992
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7NEV
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![BU of 7nev by Molmil](/molmil-images/mine/7nev) | Structure of the hemiacetal complex between the SARS-CoV-2 Main Protease and Leupeptin | Descriptor: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Guenther, S, Reinke, P.Y.A, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H.M, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashhour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Xavier, P.L, Ullah, N, Andaleeb, H, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Zaitsev-Doyle, J.J, Rogers, C, Gieseler, H, Melo, D, Monteiro, D.C.F, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schluenzen, F, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Sun, X, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | Deposit date: | 2021-02-05 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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1EMR
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![BU of 1emr by Molmil](/molmil-images/mine/1emr) | CRYSTAL STRUCTURE OF HUMAN LEUKEMIA INHIBITORY FACTOR (LIF) | Descriptor: | LEUKEMIA INHIBITORY FACTOR | Authors: | Robinson, R.C, Heath, J.K, Hawkins, N, Samal, B, Jones, E.Y, Betzel, C. | Deposit date: | 2000-03-17 | Release date: | 2001-03-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Species Variation in Receptor Binding Site Revealed by the Medium Resolution X-ray Structure of Human Leukemia Inhibitory Factor to be published
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7NFV
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![BU of 7nfv by Molmil](/molmil-images/mine/7nfv) | Structure of SARS-CoV-2 Papain-like protease PLpro | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | Authors: | Srinivasan, V, Gunther, S, Reinke, P, Werner, N, Falke, S, Brognaro, H, Ullah, N, Andaleeb, H, Perbandt, M, Alves Franca, B, Schwinzer, M, Wang, M, Sprenger, J, Lieske, J, Ginn, H, Lane, T.J, Yefanov, O, Gelisio, L, Koua, F, Saouane, S, Tolstikova, A, Groessler, M, Fleckenstein, H, Ewert, W, Trost, F, Lorenzen, K, Schubert, R, Han, H, Schmidt, C, Brings, L, Ehrt, C, Rarey, M, Galchenkova, M, Gevorkov, Y, Li, C, Perk, A, Awel, S, Hinrichs, W, Meents, A, Betzel, C. | Deposit date: | 2021-02-07 | Release date: | 2021-02-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease. Commun Biol, 5, 2022
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1EGP
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4ZXG
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![BU of 4zxg by Molmil](/molmil-images/mine/4zxg) | Ligandin binding site of PfGST | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Glutathione S-transferase, ... | Authors: | Perbandt, M, Eberle, R, Betzel, C. | Deposit date: | 2015-05-20 | Release date: | 2015-06-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High resolution structures of Plasmodium falciparum GST complexes provide novel insights into the dimer-tetramer transition and a novel ligand-binding site. J.Struct.Biol., 191, 2015
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5IN2
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1MEE
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![BU of 1mee by Molmil](/molmil-images/mine/1mee) | THE COMPLEX BETWEEN THE SUBTILISIN FROM A MESOPHILIC BACTERIUM AND THE LEECH INHIBITOR EGLIN-C | Descriptor: | CALCIUM ION, EGLIN C, MESENTERICOPEPTIDASE | Authors: | Dauter, Z, Betzel, C, Wilson, K.S. | Deposit date: | 1991-04-15 | Release date: | 1992-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-C. Acta Crystallogr.,Sect.B, 47, 1991
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8CJ4
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![BU of 8cj4 by Molmil](/molmil-images/mine/8cj4) | Crystal structure of ClpP from Staphylococcus epidermidis, tetradecamer | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit | Authors: | Alves Franca, B, Rohde, H, Betzel, C. | Deposit date: | 2023-02-12 | Release date: | 2024-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds. Sci Rep, 14, 2024
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2TEC
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![BU of 2tec by Molmil](/molmil-images/mine/2tec) | MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT | Descriptor: | CALCIUM ION, EGLIN C, THERMITASE | Authors: | Gros, P, Betzel, C, Dauter, Z, Wilson, K.S, Hol, W.G.J. | Deposit date: | 1990-10-26 | Release date: | 1992-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content. J.Mol.Biol., 210, 1989
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4FYU
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![BU of 4fyu by Molmil](/molmil-images/mine/4fyu) | Crystal structure of Thioredoxin from Wuchereria bancrofti at 2.0 Angstrom | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Thioredoxin | Authors: | Yousef, N, Prabhu, P, Ahmed, A, Iqbal, S, Betzel, C. | Deposit date: | 2012-07-05 | Release date: | 2013-08-07 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Thioredoxin from Wuchereria bancrofti at 2.0 Angstrom TO BE PUBLISHED
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4G8J
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![BU of 4g8j by Molmil](/molmil-images/mine/4g8j) | X-ray Structure of Uridine Phosphorylease from Vibrio cholerae Complexed with Thymidine at 2.12 A Resolution | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Lashkov, A.A, Gabdoulkhakov, A.G, Prokofev, I.I, Sotnichenko, S.E, Betzel, C, Mikhailov, A.M. | Deposit date: | 2012-07-23 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.119 Å) | Cite: | X-ray structure of uridine phosphorylease from Vibrio cholerae complexed with thymidine To be Published
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3M7Q
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![BU of 3m7q by Molmil](/molmil-images/mine/3m7q) | Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean sea anemone stichodactyla helianthus in complex with bovine pancreatic trypsin | Descriptor: | Cationic trypsin, Kunitz-type proteinase inhibitor SHPI-1, PHOSPHATE ION | Authors: | Garcia-Fernandez, R, Redecke, L, Pons, T, Perbandt, M, Gil, D, Talavera, A, Gonzalez, Y, de los angeles Chavez, M, Betzel, C. | Deposit date: | 2010-03-17 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor. J.Struct.Biol., 180, 2012
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2G58
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![BU of 2g58 by Molmil](/molmil-images/mine/2g58) | Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution | Descriptor: | (PHQ)IARS, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | Authors: | Prem Kumar, R, Singh, N, Somvanshi, R.K, Ethayathulla, A.S, Dey, S, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2006-02-22 | Release date: | 2006-03-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution To be Published
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2G5L
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![BU of 2g5l by Molmil](/molmil-images/mine/2g5l) | Streptavidin in complex with Nanotag | Descriptor: | (FME)(ASP)(VAL)(GLU)(ALA)(TRP)(LEU), GLYCEROL, SULFATE ION, ... | Authors: | Perbandt, M, Bruns, O, Vallazza, M, Lamla, T, Betzel, C, Erdmann, V.A. | Deposit date: | 2006-02-23 | Release date: | 2007-02-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | High resolution structure of Streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif To be Published
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8C5W
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![BU of 8c5w by Molmil](/molmil-images/mine/8c5w) | Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis in complex with Cefotaxime | Descriptor: | CEFOTAXIME, C3' cleaved, open, ... | Authors: | Schwinzer, M, Brognaro, H, Rohde, H, Betzel, C. | Deposit date: | 2023-01-10 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure and Dynamics of the Penicillin-Binding Protein 3 from Staphylococcus Epidermidis Native and in Complex with Cefotaxime and Vaborbactam Int J Appl Biol Pharm, 2023
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8C5B
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8C5O
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2R9K
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![BU of 2r9k by Molmil](/molmil-images/mine/2r9k) | Crystal Structure of Misteltoe Lectin I in Complex with Phloretamide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-hydroxyphenyl)propanamide, ... | Authors: | Meyer, A, Rypniewski, W, Celewicz, L, Erdmann, V.A, Voelter, W, Betzel, C. | Deposit date: | 2007-09-13 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The mistletoe lectin I--phloretamide structure reveals a new function of plant lectins. Biochem.Biophys.Res.Commun., 364, 2007
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439D
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![BU of 439d by Molmil](/molmil-images/mine/439d) | 5'-R(*CP*UP*GP*GP*GP*CP*GP*G)-3', 5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3' | Descriptor: | BARIUM ION, RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), RNA (5'-R(*CP*UP*GP*GP*GP*CP*GP*G)-3') | Authors: | Perbandt, M, Lorenz, S, Vallazza, M, Erdmann, V.A, Betzel, C. | Deposit date: | 1999-01-05 | Release date: | 2001-09-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of an RNA duplex with an unusual G.C pair in wobble-like conformation at 1.6 A resolution. Acta Crystallogr.,Sect.D, 57, 2001
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