5V4R
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5V87
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![BU of 5v87 by Molmil](/molmil-images/mine/5v87) | Crystal structure of LARP1-unique domain DM15 bound to m7GpppC | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | 著者 | Berman, A.J, Lahr, R.M. | 登録日 | 2017-03-21 | 公開日 | 2017-04-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs. Elife, 6, 2017
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5V7C
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2PZS
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![BU of 2pzs by Molmil](/molmil-images/mine/2pzs) | Phi29 DNA polymerase complexed with primer-template DNA (post-translocation binary complex) | 分子名称: | 5'-d(CTAACACGTAAGCAGTC)-3', 5'-d(GACTGCTTAC)-3', DNA polymerase | 著者 | Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2007-05-18 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
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2PYL
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![BU of 2pyl by Molmil](/molmil-images/mine/2pyl) | Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex) | 分子名称: | 1,2-ETHANEDIOL, 5'-d(CTGACGAATGTACA)-3', 5'-d(GACTGCTTAC(2DA))-3', ... | 著者 | Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2007-05-16 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
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2PY5
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![BU of 2py5 by Molmil](/molmil-images/mine/2py5) | Phi29 DNA polymerase complexed with single-stranded DNA | 分子名称: | 1,2-ETHANEDIOL, 5'-d(GGACTTT)-3', DNA polymerase | 著者 | Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2007-05-15 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
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2PYJ
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![BU of 2pyj by Molmil](/molmil-images/mine/2pyj) | Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex) | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-d(ACACGTAAGCAGTC)-3', ... | 著者 | Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2007-05-16 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases Embo J., 26, 2007
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4ZC4
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5C0V
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![BU of 5c0v by Molmil](/molmil-images/mine/5c0v) | Structure of the LARP1-unique domain DM15 | 分子名称: | La-related protein 1, SULFATE ION | 著者 | Lahr, R.M, Berman, A.J. | 登録日 | 2015-06-12 | 公開日 | 2015-08-05 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence. Nucleic Acids Res., 43, 2015
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8DHU
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![BU of 8dhu by Molmil](/molmil-images/mine/8dhu) | Crystal structure of LARP-DM15 from Drosophila melanogaster bound to m7GpppC | 分子名称: | La-related protein 1, MAGNESIUM ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | 著者 | Nguyen, E, Berman, A.J. | 登録日 | 2022-06-28 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution To Be Published
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8DIO
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6PW3
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1XI1
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![BU of 1xi1 by Molmil](/molmil-images/mine/1xi1) | Phi29 DNA polymerase ssDNA complex, monoclinic crystal form | 分子名称: | 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2004-09-21 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Correction of X-ray intensities from single crystals containing lattice-translocation defects Acta Crystallogr.,Sect.D, 61, 2005
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1XHX
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![BU of 1xhx by Molmil](/molmil-images/mine/1xhx) | Phi29 DNA Polymerase, orthorhombic crystal form | 分子名称: | DNA polymerase, MAGNESIUM ION, SULFATE ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2004-09-21 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29 Mol.Cell, 16, 2004
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1XHZ
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![BU of 1xhz by Molmil](/molmil-images/mine/1xhz) | Phi29 DNA polymerase, orthorhombic crystal form, ssDNA complex | 分子名称: | 5'-D(*TP*TP*TP*TP*T)-3', DNA polymerase | 著者 | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2004-09-21 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29 Mol.Cell, 16, 2004
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2F8O
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2EX3
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![BU of 2ex3 by Molmil](/molmil-images/mine/2ex3) | Bacteriophage phi29 DNA polymerase bound to terminal protein | 分子名称: | DNA polymerase, DNA terminal protein, LEAD (II) ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2005-11-07 | 公開日 | 2006-03-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition Embo J., 25, 2006
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