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PDB: 18 件
2PYJ
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Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex)
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-d(ACACGTAAGCAGTC)-3', ...
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-16
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PY5
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Phi29 DNA polymerase complexed with single-stranded DNA
分子名称: 1,2-ETHANEDIOL, 5'-d(GGACTTT)-3', DNA polymerase
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-15
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PYL
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Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex)
分子名称: 1,2-ETHANEDIOL, 5'-d(CTGACGAATGTACA)-3', 5'-d(GACTGCTTAC(2DA))-3', ...
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-16
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
5V4R
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BU of 5v4r by Molmil
Crystal structure of LARP1-unique domain DM15 bound to m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1
著者Berman, A.J, Lahr, R.M.
登録日2017-03-10
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
5V87
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Crystal structure of LARP1-unique domain DM15 bound to m7GpppC
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate
著者Berman, A.J, Lahr, R.M.
登録日2017-03-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
5V7C
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BU of 5v7c by Molmil
Crystal structure of LARP1-unique domain DM15 bound 5'TOP RNA sequence
分子名称: La-related protein 1, RNA (5'-R(*CP*UP*UP*UP*UP*CP*CP*G)-3')
著者Berman, A.J, Lahr, R.M, Al-Ashtal, H.A.
登録日2017-03-20
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
2PZS
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BU of 2pzs by Molmil
Phi29 DNA polymerase complexed with primer-template DNA (post-translocation binary complex)
分子名称: 5'-d(CTAACACGTAAGCAGTC)-3', 5'-d(GACTGCTTAC)-3', DNA polymerase
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-18
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
6PW3
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BU of 6pw3 by Molmil
LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, La-related protein 1, MAGNESIUM ION
著者Lahr, R.M, Berman, A.J.
登録日2019-07-22
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Structure, 27, 2019
4ZC4
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BU of 4zc4 by Molmil
Crystal structure of LARP1-unique domain DM15
分子名称: La-related protein 1, SULFATE ION
著者Lahr, R.M, Berman, A.J.
登録日2015-04-15
公開日2015-08-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
Nucleic Acids Res., 43, 2015
8DHU
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BU of 8dhu by Molmil
Crystal structure of LARP-DM15 from Drosophila melanogaster bound to m7GpppC
分子名称: La-related protein 1, MAGNESIUM ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate
著者Nguyen, E, Berman, A.J.
登録日2022-06-28
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution
To Be Published
8DIO
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BU of 8dio by Molmil
Crystal structure of LARP1-DM15 from Danio rerio bound to m7GpppC
分子名称: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, La ribonucleoprotein 1, translational regulator, ...
著者Nguyen, E, Berman, A.J.
登録日2022-06-29
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution
To Be Published
5C0V
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BU of 5c0v by Molmil
Structure of the LARP1-unique domain DM15
分子名称: La-related protein 1, SULFATE ION
著者Lahr, R.M, Berman, A.J.
登録日2015-06-12
公開日2015-08-05
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
Nucleic Acids Res., 43, 2015
2V4E
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BU of 2v4e by Molmil
A non-cytotoxic DsRed variant for whole-cell labeling
分子名称: RED FLUORESCENT PROTEIN DRFP583
著者Strack, R.L, Strongin, D.E, Bhattacharyya, D, Tao, W, Berman, A, Broxmeyer, H.E, Keenan, R.J, Glick, B.S.
登録日2008-09-20
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Noncytotoxic Dsred Variant for Whole-Cell Labeling.
Nat.Methods, 5, 2008
1XI1
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BU of 1xi1 by Molmil
Phi29 DNA polymerase ssDNA complex, monoclinic crystal form
分子名称: 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Correction of X-ray intensities from single crystals containing lattice-translocation defects
Acta Crystallogr.,Sect.D, 61, 2005
1XHX
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BU of 1xhx by Molmil
Phi29 DNA Polymerase, orthorhombic crystal form
分子名称: DNA polymerase, MAGNESIUM ION, SULFATE ION
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
1XHZ
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BU of 1xhz by Molmil
Phi29 DNA polymerase, orthorhombic crystal form, ssDNA complex
分子名称: 5'-D(*TP*TP*TP*TP*T)-3', DNA polymerase
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
2F8O
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BU of 2f8o by Molmil
A Native to Amyloidogenic Transition Regulated by a Backbone Trigger
分子名称: Beta-2-microglobulin
著者Eakin, C.M, Berman, A.J, Miranker, A.D.
登録日2005-12-02
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A native to amyloidogenic transition regulated by a backbone trigger.
Nat.Struct.Mol.Biol., 13, 2006
2EX3
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BU of 2ex3 by Molmil
Bacteriophage phi29 DNA polymerase bound to terminal protein
分子名称: DNA polymerase, DNA terminal protein, LEAD (II) ION
著者Kamtekar, S, Berman, A.J, Wang, J, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2005-11-07
公開日2006-03-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition
Embo J., 25, 2006

219869

件を2024-05-15に公開中

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