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PDB: 566 results

3SGC
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BU of 3sgc by Molmil
Crystal Structure of Apo Aminoglycoside-2''-Phosphotransferase Type IVa
Descriptor: APH(2'')-Id
Authors:Shi, K, Houston, D.R, Berghuis, A.M.
Deposit date:2011-06-14
Release date:2011-06-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2''-Phosphotransferase IVa Highlight the Diversity in Substrate Binding Modes among Aminoglycoside Kinases.
Biochemistry, 50, 2011
4NFI
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BU of 4nfi by Molmil
Crystal structure of human FPPS in complex with magnesium and JDS05120
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid)
Authors:Park, J, De Schutter, J.W, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2013-10-31
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS ONE, 12, 2017
3SFM
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BU of 3sfm by Molmil
Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2
Authors:Yachnin, B.J, Berghuis, A.M.
Deposit date:2011-06-13
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure.
Acta Crystallogr.,Sect.F, 67, 2011
4NFJ
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BU of 4nfj by Molmil
Crystal structure of human FPPS in complex with magnesium, JDS05120, and sulfate
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, SULFATE ION, ...
Authors:Park, J, De Schutter, J.W, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2013-10-31
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS ONE, 12, 2017
3SG8
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BU of 3sg8 by Molmil
Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type IVa Tobramycin Complex
Descriptor: APH(2'')-Id, CHLORIDE ION, TOBRAMYCIN
Authors:Shi, K, Houston, D.R, Berghuis, A.M.
Deposit date:2011-06-14
Release date:2011-06-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2''-Phosphotransferase IVa Highlight the Diversity in Substrate Binding Modes among Aminoglycoside Kinases.
Biochemistry, 50, 2011
4NFK
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BU of 4nfk by Molmil
Crystal structure of human FPPS in complex with nickel, JDS05120, and sulfate
Descriptor: Farnesyl pyrophosphate synthase, NICKEL (II) ION, SULFATE ION, ...
Authors:Park, J, De schutter, J.W, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2013-10-31
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS ONE, 12, 2017
4DTA
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BU of 4dta by Molmil
Crystal Structure of F95M Aminoglycoside-2''-Phosphotransferase Type IVa in Complex with Adenosine
Descriptor: ADENOSINE, APH(2'')-Id
Authors:Shi, K, Berghuis, A.M.
Deposit date:2012-02-20
Release date:2012-03-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases.
J.Biol.Chem., 287, 2012
4DT9
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BU of 4dt9 by Molmil
Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type IVa in Complex with Guanosine
Descriptor: APH(2'')-Id, GUANOSINE
Authors:Shi, K, Berghuis, A.M.
Deposit date:2012-02-20
Release date:2012-03-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases.
J.Biol.Chem., 287, 2012
4PVY
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BU of 4pvy by Molmil
Crystal structure of human FPPS in complex with [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid)
Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Rodionov, D, Park, J, De Schutter, J.W, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2014-03-18
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS ONE, 12, 2017
3VFI
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BU of 3vfi by Molmil
Crystal Structure of a Metagenomic Thioredoxin
Descriptor: thioredoxin
Authors:Craig, T.K, Gardberg, A, Lorimer, D.D, Burgin Jr, A.B, Segall, A, Rohwer, F.
Deposit date:2012-01-09
Release date:2013-01-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of a Metagenomic Thioredoxin
To be Published
4PVX
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BU of 4pvx by Molmil
Crystal structure of human FPPS in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)
Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Rodionov, D, Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2014-03-18
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS ONE, 12, 2017
4H5C
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BU of 4h5c by Molmil
Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2012-09-18
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
4H5E
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BU of 4h5e by Molmil
Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate
Descriptor: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ...
Authors:Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2012-09-18
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
4H5D
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BU of 4h5d by Molmil
Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
Deposit date:2012-09-18
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
3OTO
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BU of 3oto by Molmil
Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
Descriptor: 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G.
Deposit date:2010-09-13
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
3Q2J
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BU of 3q2j by Molmil
Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex
Descriptor: Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE
Authors:Fong, D.H, Xiong, B, Hwang, J, Berghuis, A.M.
Deposit date:2010-12-20
Release date:2011-05-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1501 Å)
Cite:Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Plos One, 6, 2011

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数据于2024-07-24公开中

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