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PDB: 71 件
7S77
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Crystal structure of the G391V variant of human PGM-1
分子名称: Phosphoglucomutase-1, SULFATE ION
著者Stiers, K.M, Beamer, L.J.
登録日2021-09-15
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Effects of the T337M and G391V disease-related variants on human phosphoglucomutase 1: structural disruptions large and small.
Acta Crystallogr.,Sect.F, 78, 2022
5VIN
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BU of 5vin by Molmil
Crystal Structure of the R515Q missense variant of human PGM1
分子名称: COBALT (II) ION, GLYCEROL, Phosphoglucomutase-1, ...
著者Stiers, K.M, Beamer, L.J.
登録日2017-04-17
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.60004282 Å)
主引用文献A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics.
Structure, 26, 2018
5VEC
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BU of 5vec by Molmil
Crystal Structure of the R515L missense variant of human PGM1
分子名称: GLYCEROL, MAGNESIUM ION, Phosphoglucomutase-1, ...
著者Stiers, K.M, Beamer, L.J.
登録日2017-04-04
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.20001626 Å)
主引用文献A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics.
Structure, 26, 2018
2FLU
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BU of 2flu by Molmil
Crystal Structure of the Kelch-Neh2 Complex
分子名称: Kelch-like ECH-associated protein 1, Nrf2
著者Li, X, Lo, J, Beamer, L, Hannink, M.
登録日2006-01-06
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Embo J., 25, 2006
1MFZ
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BU of 1mfz by Molmil
Partially refined 2.8 A Crystal structure of GDP-mannose dehydrogenase from P. aeruginosa
分子名称: GDP-mannose 6-dehydrogenase, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER
著者Snook, C.F, Tipton, P.A, Beamer, L.J.
登録日2002-08-14
公開日2003-05-06
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of GDP-mannose dehydrogenase: A key enzyme in alginate biosynthesis of P. aeruginosa
Biochemistry, 42, 2003
1MV8
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BU of 1mv8 by Molmil
1.55 A crystal structure of a ternary complex of GDP-mannose dehydrogenase from Psuedomonas aeruginosa
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, GDP-mannose 6-dehydrogenase, ...
著者Snook, C.F, Tipton, P.A, Beamer, L.J.
登録日2002-09-24
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The crystal structure of GDP-mannose dehydrogenase: A key enzyme in alginate biosynthesis of P. aeruginosa
Biochemistry, 42, 2003
1MUU
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BU of 1muu by Molmil
2.0 A crystal structure of GDP-mannose dehydrogenase
分子名称: GDP-mannose 6-dehydrogenase, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ...
著者Snook, C.F, Tipton, P.A, Beamer, L.J.
登録日2002-09-24
公開日2003-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of GDP-mannose dehydrogenase: A key enzyme of alginate biosynthesis in P. aeruginosa
Biochemistry, 42, 2003
3PDK
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BU of 3pdk by Molmil
crystal structure of phosphoglucosamine mutase from B. anthracis
分子名称: PHOSPHATE ION, Phosphoglucosamine mutase
著者Mehra-Chaudhary, R, Mick, J, Tanner, J.J, Henzl, M, Beamer, L.J.
登録日2010-10-22
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Bacillus anthracis Phosphoglucosamine Mutase, an Enzyme in the Peptidoglycan Biosynthetic Pathway.
J.Bacteriol., 193, 2011
2H5A
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BU of 2h5a by Molmil
Complex of the enzyme PMM/PGM with xylose 1-phosphate
分子名称: 1-O-phosphono-alpha-D-xylopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Regni, C, Shackelford, G.S, Beamer, L.J.
登録日2006-05-25
公開日2006-08-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor.
Acta Crystallogr.,Sect.F, 62, 2006
3C04
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BU of 3c04 by Molmil
Structure of the P368G mutant of PMM/PGM from P. aeruginosa
分子名称: Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Mehra-Chaudhary, R, Beamer, L.J.
登録日2008-01-18
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa.
Biochemistry, 47, 2008
3BKQ
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BU of 3bkq by Molmil
Structure of the P368G mutant of PMM/PGM in complex with its substrate
分子名称: 1-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Mehra-Chaudhary, R, Beamer, L.J.
登録日2007-12-07
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa.
Biochemistry, 47, 2008
3RSM
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BU of 3rsm by Molmil
Crystal structure of S108C mutant of PMM/PGM
分子名称: PHOSPHATE ION, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Akella, A, Anbanandam, A, Kelm, A, Wei, Y, Mehra-Chaudhary, R, Beamer, L, Van Doren, S.
登録日2011-05-02
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Solution NMR of a 463-residue phosphohexomutase: domain 4 mobility, substates, and phosphoryl transfer defect.
Biochemistry, 51, 2012
1P5D
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BU of 1p5d by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
分子名称: 1-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase, ZINC ION
著者Regni, C, Tipton, P.A, Beamer, L.J.
登録日2003-04-25
公開日2004-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1P5G
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BU of 1p5g by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase, ZINC ION
著者Regni, C, Tipton, P.A, Beamer, L.J.
登録日2003-04-26
公開日2004-01-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1PCJ
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BU of 1pcj by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
分子名称: 1-O-phosphono-alpha-D-mannopyranose, Phosphomannomutase, ZINC ION
著者Regni, C, Tipton, P.A, Beamer, L.J.
登録日2003-05-16
公開日2004-01-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1PCM
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BU of 1pcm by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
分子名称: 6-O-phosphono-alpha-D-mannopyranose, Phosphomannomutase, ZINC ION
著者Regni, C, Tipton, P.A, Beamer, L.J.
登録日2003-05-16
公開日2004-01-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
2FKF
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BU of 2fkf by Molmil
Phosphomannomutase/Phosphoglucomutase from Pseudomonas aeruginosa with alpha-D-glucose 1,6-bisphosphate bound
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Regni, C.A, Beamer, L.J.
登録日2006-01-04
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.
J.Biol.Chem., 281, 2006
2FKM
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BU of 2fkm by Molmil
PMM/PGM S108D mutant with alpha-d-glucose 1,6-bisphosphate bound
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Regni, C.A, Beamer, L.J.
登録日2006-01-04
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.
J.Biol.Chem., 281, 2006
6UXJ
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BU of 6uxj by Molmil
Structure of serine hydroxymethyltransferase 8 from Glycine max cultivar Essex complexed with PLP-glycine and 5-formyltetrahydrofolate
分子名称: 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ...
著者Korasick, D.A, Tanner, J.J, Beamer, L.J.
登録日2019-11-07
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode.
J.Biol.Chem., 295, 2020
5HSH
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BU of 5hsh by Molmil
Crystal structure of the G291R mutant of human phosphoglucomutase 1
分子名称: Phosphoglucomutase-1, SULFATE ION
著者Stiers, K.M, Beamer, L.J.
登録日2016-01-25
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency.
J.Mol.Biol., 428, 2016
5VBI
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BU of 5vbi by Molmil
Crystal Structure of the R515W missense variant of human PGM1
分子名称: GLYCEROL, MAGNESIUM ION, Phosphoglucomutase-1, ...
著者Stiers, K.M, Beamer, L.J.
登録日2017-03-29
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75000083 Å)
主引用文献A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics.
Structure, 26, 2018
5VG7
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BU of 5vg7 by Molmil
Crystal Structure of the R503Q missense variant of human PGM1
分子名称: GLYCEROL, MAGNESIUM ION, Phosphoglucomutase-1, ...
著者Stiers, K.M, Beamer, L.J.
登録日2017-04-10
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95000327 Å)
主引用文献A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics.
Structure, 26, 2018
6UXL
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BU of 6uxl by Molmil
Structure of serine hydroxymethyltransferase 8 from Glycine max cultivar Forrest complexed with PLP-Glycine
分子名称: N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], Serine hydroxymethyltransferase
著者Korasick, D.A, Tanner, J.J, Beamer, L.J.
登録日2019-11-07
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode.
J.Biol.Chem., 295, 2020
3NA5
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BU of 3na5 by Molmil
Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of several human pathogens.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Phosphoglucomutase
著者Mehra-Chaudhary, R, Beamer, L.J.
登録日2010-06-01
公開日2011-02-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Proteins, 79, 2011
1K2Y
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BU of 1k2y by Molmil
Crystal Structure of Phosphomannomutase/Phosphoglucomutase S108A mutant from P. aeruginosa
分子名称: L(+)-TARTARIC ACID, ZINC ION, phosphomannomutase
著者Regni, C, Tipton, P.A, Beamer, L.J.
登録日2001-09-30
公開日2002-02-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of PMM/PGM: an enzyme in the biosynthetic pathway of P. aeruginosa virulence factors.
Structure, 10, 2002

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