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PDB: 74 件

8FSD
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P130R mutant of soybean SHMT8 in complex with PLP-glycine and formylTHF
分子名称: 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ...
著者Beamer, L.J, Korasick, D.A.
登録日2023-01-09
公開日2023-10-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance.
Febs J., 291, 2024
9CE6
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Key structural role for the conserved cis-proline of soybean serine hydroxymethyltransferase
分子名称: Serine hydroxymethyltransferase
著者Beamer, L.J, Samarakoon, V.
登録日2024-06-26
公開日2024-10-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Key structural role of a conserved cis-proline revealed by the P285S variant of soybean serine hydroxymethyltransferase 8.
Biochem.J., 481, 2024
9CG8
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BU of 9cg8 by Molmil
CRYSTAL STRUCTURE OF THE P285S VARIANT OF SERINE HYDROXYMETHYLTRANSFERASE 8 FROM SOYBEAN CULTIVAR FORREST
分子名称: Serine hydroxymethyltransferase
著者Beamer, L.J, Samarakoon, V, Owuocha, L.F.
登録日2024-06-28
公開日2024-10-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Key structural role of a conserved cis-proline revealed by the P285S variant of soybean serine hydroxymethyltransferase 8.
Biochem.J., 481, 2024
5JN5
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BU of 5jn5 by Molmil
Crystal structure of the D263Y missense variant of human PGM1
分子名称: CALCIUM ION, Phosphoglucomutase-1, SULFATE ION
著者Beamer, L.J, Stiers, K.M.
登録日2016-04-29
公開日2017-02-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Asp263 missense variants perturb the active site of human phosphoglucomutase 1.
FEBS J., 284, 2017
5EPC
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BU of 5epc by Molmil
Crystal structure of wild-type human phosphoglucomutase 1
分子名称: GLYCEROL, MAGNESIUM ION, Phosphoglucomutase-1, ...
著者Beamer, L.J.
登録日2015-11-11
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency.
J.Mol.Biol., 428, 2016
5F9C
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BU of 5f9c by Molmil
Crystal structure of the G121R mutant of human phosphoglucomutase 1
分子名称: GLYCEROL, MAGNESIUM ION, Phosphoglucomutase-1, ...
著者Beamer, L.J.
登録日2015-12-09
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency.
J.Mol.Biol., 428, 2016
1LMB
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BU of 1lmb by Molmil
REFINED 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR-OPERATOR COMPLEX
分子名称: DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR)
著者Beamer, L.J, Pabo, C.O.
登録日1991-11-05
公開日1991-11-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8 A crystal structure of the lambda repressor-operator complex.
J.Mol.Biol., 227, 1992
3OLP
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BU of 3olp by Molmil
Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of multiple human pathogens
分子名称: MAGNESIUM ION, PHOSPHATE ION, Phosphoglucomutase
著者Beamer, L.J, Mehra-Chaudhary, R.
登録日2010-08-26
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Proteins, 79, 2011
1BP1
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BU of 1bp1 by Molmil
CRYSTAL STRUCTURE OF BPI, THE HUMAN BACTERICIDAL PERMEABILITY-INCREASING PROTEIN
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN
著者Beamer, L.J, Carroll, S.F, Eisenberg, D.
登録日1997-04-08
公開日1997-09-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution.
Science, 276, 1997
6UO6
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BU of 6uo6 by Molmil
Crystal Structure of the R422Q missense variant of human PGM1
分子名称: MAGNESIUM ION, Phosphoglucomutase-1, SULFATE ION
著者Beamer, L.J, Stiers, K.M.
登録日2019-10-14
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A missense variant remote from the active site impairs stability of human phosphoglucomutase 1.
J. Inherit. Metab. Dis., 43, 2020
2H4L
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BU of 2h4l by Molmil
Complex of PMM/PGM with ribose 1-phosphate
分子名称: 1-O-phosphono-alpha-D-ribofuranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
著者Beamer, L.J.
登録日2006-05-24
公開日2006-08-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor.
Acta Crystallogr.,Sect.F, 62, 2006
5TR2
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BU of 5tr2 by Molmil
Crystal structure of the D263G missense variant of human PGM1
分子名称: CALCIUM ION, GLYCEROL, Phosphoglucomutase-1, ...
著者Beamer, L.J, Stiers, K.M.
登録日2016-10-25
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Asp263 missense variants perturb the active site of human phosphoglucomutase 1.
FEBS J., 284, 2017
6MNV
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BU of 6mnv by Molmil
Crystal structure of X. citri phosphoglucomutase in complex with CH2FG1P
分子名称: 1-deoxy-1-fluoro-2-O-phosphono-alpha-D-gluco-hept-2-ulopyranose, MAGNESIUM ION, Phosphomannomutase/phosphoglucomutase, ...
著者Beamer, L, Stiers, K.
登録日2018-10-03
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Inhibitory Evaluation of alpha PMM/PGM fromPseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study.
J.Org.Chem., 84, 2019
6MLF
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BU of 6mlf by Molmil
Crystal structure of X. citri phosphoglucomutase in complex with 6-fluoro glucose 1-phosphate
分子名称: 6-deoxy-6-fluoro-1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase
著者Beamer, L, Stiers, K.
登録日2018-09-27
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inhibitory Evaluation of alpha PMM/PGM fromPseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study.
J.Org.Chem., 84, 2019
6MLW
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BU of 6mlw by Molmil
Crystal structure of X. citri phosphoglucomutase in complex with 2-fluoro mannosyl-1-methyl-phosphonic acid
分子名称: 2,6-anhydro-5,7-dideoxy-5-fluoro-7-phosphono-D-glycero-D-manno-heptitol, MAGNESIUM ION, Phosphoglucomutase
著者Beamer, L, Stiers, K.
登録日2018-09-28
公開日2019-07-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Inhibitory Evaluation of alpha PMM/PGM fromPseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study.
J.Org.Chem., 84, 2019
6MLH
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BU of 6mlh by Molmil
Crystal structure of X. citri phosphoglucomutase in complex with GLUCOPYRANOSYL-1-METHYL-PHOSPHONIC ACID
分子名称: (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol, MAGNESIUM ION, Phosphoglucomutase
著者Beamer, L, Stiers, K.
登録日2018-09-27
公開日2019-07-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Inhibitory Evaluation of alpha PMM/PGM fromPseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study.
J.Org.Chem., 84, 2019
6N1E
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BU of 6n1e by Molmil
Crystal structure of X. citri phosphoglucomutase in complex with 1-methyl-glucose 6-phosphate
分子名称: 1-deoxy-7-O-phosphono-alpha-D-gluco-hept-2-ulopyranose, MAGNESIUM ION, Phosphomannomutase/phosphoglucomutase
著者Beamer, L.J, Stiers, K.M.
登録日2018-11-08
公開日2019-05-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d-Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition.
Acs Omega, 4, 2019
1U6D
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BU of 1u6d by Molmil
Crystal structure of the Kelch domain of human Keap1
分子名称: kelch-like ECH-associated protein 1
著者Li, X, Zhang, D, Hannink, M, Beamer, L.J.
登録日2004-07-29
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the kelch domain of human keap1
J.Biol.Chem., 279, 2004
1EWF
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BU of 1ewf by Molmil
THE 1.7 ANGSTROM CRYSTAL STRUCTURE OF BPI
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN
著者Kleiger, G, Beamer, L.J, Grothe, R, Mallick, P, Eisenberg, D.
登録日2000-04-25
公開日2000-06-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 1.7 A crystal structure of BPI: a study of how two dissimilar amino acid sequences can adopt the same fold.
J.Mol.Biol., 299, 2000
8DOM
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BU of 8dom by Molmil
Structure of the N358Y single variant ofserine hydroxymethyltransferase 8 from Glycine max cultivar Essex complexed with PLP
分子名称: 1,2-ETHANEDIOL, Serine hydroxymethyltransferase
著者Korasick, D.A, Beamer, L.J.
登録日2022-07-13
公開日2023-07-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance.
Febs J., 291, 2024
8TQF
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BU of 8tqf by Molmil
Crystal structure of Soybean SHMT8 in complex with PLP-glycine and diglutamylated 5-formyltetrahydrofolate
分子名称: 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6R)-2-amino-5-formyl-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-glutamic acid, ...
著者Owuocha, L.F, Beamer, L.J.
登録日2023-08-07
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural insights into high affinity binding of polyglutamylated tetrahydrofolate to soybean serine hydroxymethyltransferase
To Be Published
3NA5
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BU of 3na5 by Molmil
Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of several human pathogens.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Phosphoglucomutase
著者Mehra-Chaudhary, R, Beamer, L.J.
登録日2010-06-01
公開日2011-02-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Proteins, 79, 2011
4MRQ
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BU of 4mrq by Molmil
Crystal Structure of wild-type unphosphorylated PMM/PGM
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, ...
著者Lee, Y, Beamer, L.
登録日2013-09-17
公開日2014-01-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Promotion of enzyme flexibility by dephosphorylation and coupling to the catalytic mechanism of a phosphohexomutase.
J.Biol.Chem., 289, 2014
1ZGK
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BU of 1zgk by Molmil
1.35 angstrom structure of the Kelch domain of Keap1
分子名称: Kelch-like ECH-associated protein 1
著者Li, X, Bottoms, C.A, Hannink, M, Beamer, L.J.
登録日2005-04-21
公開日2005-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1.
Acta Crystallogr.,Sect.D, 61, 2005
4IL8
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BU of 4il8 by Molmil
Crystal structure of an H329A mutant of p. aeruginosa PMM/PGM
分子名称: GLYCEROL, MAGNESIUM ION, Phosphomannomutase/phosphoglucomutase
著者Lee, Y, Mehra-Chaudhary, R, Furdui, C, Beamer, L.
登録日2012-12-29
公開日2013-08-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of an essential active-site residue in the alpha-D-phosphohexomutase enzyme superfamily.
Febs J., 280, 2013

 

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