6UO6

Crystal Structure of the R422Q missense variant of human PGM1

Summary for 6UO6

• Entry DOI: 10.2210/pdb6uo6/pdb
• Related: 5epc
• Descriptor: Phosphoglucomutase-1, MAGNESIUM ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: isomerase, enzyme, missense variant
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 129142.44

Authors

Beamer, L.J.,Stiers, K.M. (deposition date: 2019-10-14, release date: 2020-03-04, Last modification date: 2023-10-11)

• Primary citation: Stiers, K.M.,Hansen, R.P.,Daghlas, B.A.,Mason, K.N.,Zhu, J.S.,Jakeman, D.L.,Beamer, L.J.; A missense variant remote from the active site impairs stability of human phosphoglucomutase 1.; J. Inherit. Metab. Dis., 43:861-870, 2020; PubMed: 32057119; DOI: 10.1002/jimd.12222

Experimental method

X-RAY DIFFRACTION (2.15 Å)