6UO6

Crystal Structure of the R422Q missense variant of human PGM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoglucomutase-1	polymer	585	64162.7	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880) In PDB	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4		water	water		18.0	625	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	initiating methionine
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Gln 422	Arg 422	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128325.3
Non-Polymers*	Number of molecules	10
	Total formula weight	817.1
All*	Total formula weight	129142.4

*Water molecules are not included.