6A1O
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![BU of 6a1o by Molmil](/molmil-images/mine/6a1o) | Crystal structures of disordered Z-type helices | Descriptor: | DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ... | Authors: | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | Deposit date: | 2018-06-07 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
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9AUR
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![BU of 9aur by Molmil](/molmil-images/mine/9aur) | Crystal structure of loop-closed A21 2'-OMe dumbbell RNA bridged by glycine | Descriptor: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | Authors: | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | Deposit date: | 2024-02-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
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9AUS
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![BU of 9aus by Molmil](/molmil-images/mine/9aus) | Crystal structure of loop-closed dumbbell RNA bridged by glycine | Descriptor: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | Authors: | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | Deposit date: | 2024-02-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
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6EDE
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![BU of 6ede by Molmil](/molmil-images/mine/6ede) | tRNA 2'-phosphotransferase | Descriptor: | Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | Authors: | Shuman, S, Goldgur, Y, Banerjee, A. | Deposit date: | 2018-08-09 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.553 Å) | Cite: | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
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2YLL
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![BU of 2yll by Molmil](/molmil-images/mine/2yll) | Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis | Descriptor: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BETA-N-ACETYLHEXOSAMINIDASE, ... | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2011-06-02 | Release date: | 2011-09-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
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5YPW
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![BU of 5ypw by Molmil](/molmil-images/mine/5ypw) | Crystal structure of IlvN.Val-1b | Descriptor: | Acetolactate synthase isozyme 1 small subunit, VALINE | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | Deposit date: | 2017-11-03 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
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7LFQ
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![BU of 7lfq by Molmil](/molmil-images/mine/7lfq) | Pyrococcus RNA ligase | Descriptor: | DNA (5'-D(*AP*TP*GP*TP*CP*C)-3'), POTASSIUM ION, RNA-splicing ligase RtcB, ... | Authors: | Goldgur, Y, Shuman, S, Banerjee, A. | Deposit date: | 2021-01-18 | Release date: | 2021-03-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of 3'-PO 4 /5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide. Rna, 27, 2021
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5YPY
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![BU of 5ypy by Molmil](/molmil-images/mine/5ypy) | Crystal structure of IlvN. Val-1c | Descriptor: | Acetolactate synthase isozyme 1 small subunit, VALINE | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | Deposit date: | 2017-11-04 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.966 Å) | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
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5YUM
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![BU of 5yum by Molmil](/molmil-images/mine/5yum) | Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs | Descriptor: | Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | Deposit date: | 2017-11-22 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.432 Å) | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
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7KHM
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![BU of 7khm by Molmil](/molmil-images/mine/7khm) | Crystal structure of hDHHS20 bound to palmitoyl CoA | Descriptor: | Isoform 4 of Palmitoyltransferase ZDHHC20, PHOSPHATE ION, Palmitoyl-CoA, ... | Authors: | Lee, C.-J, Banerjee, A. | Deposit date: | 2020-10-21 | Release date: | 2022-02-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase. Proc.Natl.Acad.Sci.USA, 119, 2022
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2YL6
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![BU of 2yl6 by Molmil](/molmil-images/mine/2yl6) | Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis | Descriptor: | 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BETA-N-ACETYLHEXOSAMINIDASE, ... | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2011-05-31 | Release date: | 2011-09-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
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2YL9
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![BU of 2yl9 by Molmil](/molmil-images/mine/2yl9) | INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-N-ACETYLHEXOSAMINIDASE | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2011-06-01 | Release date: | 2011-09-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
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2YL5
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![BU of 2yl5 by Molmil](/molmil-images/mine/2yl5) | Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis | Descriptor: | 1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, MAGNESIUM ION | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2011-05-31 | Release date: | 2011-09-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
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1BE6
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![BU of 1be6 by Molmil](/molmil-images/mine/1be6) | TRANS-CINNAMOYL-SUBTILISIN IN ANHYDROUS ACETONITRILE | Descriptor: | ACETONITRILE, CALCIUM ION, PHENYLETHYLENECARBOXYLIC ACID, ... | Authors: | Schmitke, J.L, Stern, L.J, Klibanov, A.M. | Deposit date: | 1998-05-20 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water. Proc.Natl.Acad.Sci.USA, 95, 1998
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5CLM
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![BU of 5clm by Molmil](/molmil-images/mine/5clm) | 1,4-Oxazine BACE1 inhibitors | Descriptor: | Beta-secretase 1, CHLORIDE ION, IODIDE ION, ... | Authors: | Rombouts, F, Tresadern, G, Delgado, O, Martinez Lamenca, C, Van Gool, M, Garcia-Molina, A, Alonso De Diego, S, Oehlrich, D, Prokopcova, H, Alonso, J.M, Austin, N, Borghys, H, Van Brandt, S, Surkyn, M, De Cleyn, M, Vos, A, Alexander, R, MacDonald, G, Moechars, D, Trabanco, A, Gijsen, H. | Deposit date: | 2015-07-16 | Release date: | 2015-09-30 | Last modified: | 2015-11-04 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | 1,4-Oxazine beta-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads. J.Med.Chem., 58, 2015
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5W7I
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![BU of 5w7i by Molmil](/molmil-images/mine/5w7i) | X-ray structure of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide | Descriptor: | Palmitoyltransferase ZDHHC17, Snap25b-111-120 | Authors: | Verardi, R, Kim, J.-S, Ghirlando, R, Banerjee, A. | Deposit date: | 2017-06-20 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 25, 2017
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5W7J
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![BU of 5w7j by Molmil](/molmil-images/mine/5w7j) | X-ray structure of the E89A variant of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide | Descriptor: | Palmitoyltransferase ZDHHC17, Snap25b-111-120 | Authors: | Verardi, R, Kim, J.-S, Ghirlando, R, Banerjee, A. | Deposit date: | 2017-06-20 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 25, 2017
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4MF3
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![BU of 4mf3 by Molmil](/molmil-images/mine/4mf3) | Crystal Structure of Human GRIK1 complexed with a 6-(tetrazolyl)aryl decahydroisoquinoline antagonist | Descriptor: | (3S,4aS,6S,8aR)-6-[3-chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydroisoquinoline-3-carboxylic acid, Glutamate receptor ionotropic, kainate 1 | Authors: | Martinez-Perez, J.A, Iyengar, S, Shannon, H.E, Bleakman, D, Alt, A, Clawson, D.K, Arnold, B.M, Bell, M.G, Bleisch, T.J, Castano, A.M, Del Prado, M, Dominguez, E, Escribano, A.M, Filla, S.A, Ho, K.H, Hudziak, K.J, Jones, C.K, Katofiasc, M.A, Mateo, A, Mathes, B.M, Mattiuz, E.L, Ogden, A.M.L, Phebus, L.A, Simmons, R.M.A, Stack, D.R, Stratford, R.E, Winter, M.A, Wu, Z, Ornstein, P.L. | Deposit date: | 2013-08-27 | Release date: | 2014-05-07 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy. Bioorg.Med.Chem.Lett., 23, 2013
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5VJV
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![BU of 5vjv by Molmil](/molmil-images/mine/5vjv) | Rhizobiales-like phosphatase 2 | Descriptor: | PHOSPHATE ION, Rhizobiales-like phosphatase 2, ZINC ION | Authors: | Ng, K.K.S, Labandera, A, Moorhead, G. | Deposit date: | 2017-04-20 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the preference of the Arabidopsis thalianaphosphatase RLPH2 for tyrosine-phosphorylated substrates. Sci Signal, 11, 2018
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5VJW
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![BU of 5vjw by Molmil](/molmil-images/mine/5vjw) | |
2YL8
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![BU of 2yl8 by Molmil](/molmil-images/mine/2yl8) | Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, BETA-N-ACETYLHEXOSAMINIDASE, ... | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2011-05-31 | Release date: | 2011-09-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
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1AF4
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![BU of 1af4 by Molmil](/molmil-images/mine/1af4) | CRYSTAL STRUCTURE OF SUBTILISIN CARLSBERG IN ANHYDROUS DIOXANE | Descriptor: | 1,4-DIETHYLENE DIOXIDE, CALCIUM ION, SUBTILISIN CARLSBERG | Authors: | Schmitke, J.L, Stern, L.J, Klibanov, A.M. | Deposit date: | 1997-03-21 | Release date: | 1997-06-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of subtilisin Carlsberg in anhydrous dioxane and its comparison with those in water and acetonitrile. Proc.Natl.Acad.Sci.USA, 94, 1997
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1BQB
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![BU of 1bqb by Molmil](/molmil-images/mine/1bqb) | AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE | Descriptor: | CALCIUM ION, PROTEIN (AUREOLYSIN), ZINC ION | Authors: | Medrano, F.J, Banbula, A, Potempa, J, Travis, J, Bode, W. | Deposit date: | 1998-07-14 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution. Structure, 6, 1998
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5TO6
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![BU of 5to6 by Molmil](/molmil-images/mine/5to6) | Structure of the TPR oligomerization domain | Descriptor: | Nucleoprotein TPR | Authors: | Pal, K, Bandyopadhyay, A, Xu, Q, Zhou, X.E, Melcher, K, Xu, H.E. | Deposit date: | 2016-10-16 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases. Structure, 25, 2017
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7KW9
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![BU of 7kw9 by Molmil](/molmil-images/mine/7kw9) | NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis in complex with NAD+ | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase | Authors: | Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R. | Deposit date: | 2020-11-30 | Release date: | 2021-10-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity. Nucleic Acids Res., 49, 2021
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