4NS4
 
 | | Crystal structure of cold-active estarase from Psychrobacter cryohalolentis K5T | | 分子名称: | Alpha/beta hydrolase fold protein | | 著者 | Boyko, K.M, Petrovskaya, L.E, Gorbacheva, M.A, Korgenevsky, D.A, Novototskaya-Vlasova, K.A, Rivkina, E.M, Dolgikh, D.A, Kirpichnikov, M.P, Lipkin, A.V, Popov, V.O. | | 登録日 | 2013-11-28 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Three-dimentional structure of an esterse from Psychrobacter cryohalolentis K5T provides clues to unusual thermostability of a cold-active enzyme
To be Published
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1CK7
 | | GELATINASE A (FULL-LENGTH) | | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN (GELATINASE A), ... | | 著者 | Morgunova, E, Tuuttila, A, Bergmann, U, Isupov, M, Lindqvist, Y, Schneider, G, Tryggvason, K. | | 登録日 | 1999-04-28 | | 公開日 | 1999-08-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed.
Science, 284, 1999
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1EAK
 | | Catalytic domain of proMMP-2 E404Q mutant | | 分子名称: | 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, INHIBITOR PEPTIDE, ... | | 著者 | Bergmann, U, Tuuttila, A, Tryggvason, K, Morgunova, E. | | 登録日 | 2001-07-12 | | 公開日 | 2002-08-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Crystal Structure of Human Mmp-2 Reveals a New P
To be Published
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1GXD
 | | proMMP-2/TIMP-2 complex | | 分子名称: | 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, METALLOPROTEINASE INHIBITOR 2, ... | | 著者 | Morgunova, E, Tuuttila, A, Bergmann, U, Tryggvason, K. | | 登録日 | 2002-04-02 | | 公開日 | 2002-07-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Insight Into the Complex Formation of Latent Matrix Metalloproteinase 2 with Tissue Inhibitor of Metalloproteinase 2
Proc.Natl.Acad.Sci.USA, 99, 2002
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8TN9
 | | Structural architecture of the acidic region of the B domain of coagulation factor V | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor V | | 著者 | Mohammed, B.M, Basore, K, Summers, B, Pelc, L.A, Di Cera, E. | | 登録日 | 2023-08-01 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural architecture of the acidic region of the B domain of coagulation factor V.
J.Thromb.Haemost., 22, 2024
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2OYA
 | | Crystal structure analysis of the dimeric form of the SRCR domain of mouse MARCO | | 分子名称: | Macrophage receptor MARCO, SULFATE ION | | 著者 | Ojala, J.R.M, Pikkarainen, T, Tuuttila, A, Sandalova, T, Tryggvason, K. | | 登録日 | 2007-02-21 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition.
J.Biol.Chem., 282, 2007
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8FPT
 | | STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | | 分子名称: | Alpha-synuclein | | 著者 | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | | 登録日 | 2023-01-05 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Biorxiv, 2023
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8G3G
 | | CryoEM structure of yeast recombination mediator Rad52 | | 分子名称: | DNA repair and recombination protein RAD52 | | 著者 | Deveryshetty, J, Basore, K, Rau, M, Fitzpatrick, J.A.J, Antony, E. | | 登録日 | 2023-02-07 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
Nat Commun, 14, 2023
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8UF7
 | | Cryo-EM structure of POmAb, a Type-I anti-prothrombin antiphospholipid antibody, bound to kringle-1 of human prothrombin | | 分子名称: | POmAb Heavy Chain, POmAb Light Chain, Prothrombin | | 著者 | Kumar, S, Summers, B, Basore, K, Pozzi, N. | | 登録日 | 2023-10-03 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure and functional basis of prothrombin recognition by a type I antiprothrombin antiphospholipid antibody.
Blood, 143, 2024
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4PP7
 | | Highly Potent and Selective 3-N-methylquinazoline-4(3H)-one Based Inhibitors of B-RafV600E Kinase | | 分子名称: | N-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | 著者 | Wenglowsky, S, Ren, L, Grina, J, Hansen, J.D, Laird, E.R, Moreno, D, Dinkel, V, Gloor, S.L, Hastings, G, Rana, S, Rasor, K, Sturgis, H.L, Voegtli, W.C, Vigers, G.P.A, Willis, B, Mathieu, S, Rudolph, J. | | 登録日 | 2014-02-26 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
Bioorg.Med.Chem.Lett., 24, 2014
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