4KMN
 
 | | Structure of cIAP1-BIR3 and inhibitor | | 分子名称: | (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, Baculoviral IAP repeat-containing protein 2, PHOSPHATE ION, ... | | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | | 登録日 | 2013-05-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.523 Å) | | 主引用文献 | Structure of cIAP1-BIR3 and inhibitor
To be Published
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7YFH
 | | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | 著者 | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | | 登録日 | 2022-07-08 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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3JB3
 | | Atomic model of cytoplasmic polyhedrosis virus with SAM, GTP and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Capsid protein VP1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Yu, X.K, Jiang, J.S, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-07-06 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A putative ATPase mediates RNA transcription and capping in a dsRNA virus.
Elife, 4, 2015
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7YKD
 | | Cryo-EM structure of the human chemerin receptor 1 complex with the C-terminal nonapeptide of chemerin | | 分子名称: | CHOLESTEROL, Chemerin-like receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Chen, G, Liao, Q, Ye, R.D, Wang, J. | | 登録日 | 2022-07-22 | | 公開日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5V5L
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4FJZ
 | | Crystal structure of PI3K-gamma in complex with pyrrolo-pyridine inhibitor 63 | | 分子名称: | 1'-[7-fluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-yl]-6'-(morpholin-4-yl)-1',2,2',3,5,6-hexahydrospiro[pyran-4,3'-pyrrolo[3,2-b]pyridine], Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | | 登録日 | 2012-06-12 | | 公開日 | 2012-10-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors
J.Med.Chem., 55, 2012
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5UN9
 | | The crystal structure of human O-GlcNAcase in complex with Thiamet-G | | 分子名称: | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, Protein O-GlcNAcase | | 著者 | Li, B, Jiang, J. | | 登録日 | 2017-01-30 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
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4PLX
 | | Crystal structure of the triple-helical stability element at the 3' end of MALAT1 | | 分子名称: | Core ENE hairpin and A-rich tract from MALAT1 | | 著者 | Brown, J.A, Bulkley, D, Wang, J, Valenstein, M.L, Yario, T.A, Steitz, T.A, Steitz, J.A. | | 登録日 | 2014-05-19 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.
Nat.Struct.Mol.Biol., 21, 2014
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4BEV
 | | ATPase crystal structure with bound phosphate analogue | | 分子名称: | COPPER EFFLUX ATPASE, MAGNESIUM ION, TRIFLUOROMAGNESATE | | 著者 | Mattle, D, Drachmann, N.D, Liu, X.Y, Gourdon, P, Pedersen, B.P, Morth, P, Wang, J, Nissen, P. | | 登録日 | 2013-03-12 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.583 Å) | | 主引用文献 | ATPase Crystal Structure with Bound Phosphate Analogue
To be Published
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6BLI
 | | RSV G peptide bound to Fab CB002.5 | | 分子名称: | CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G | | 著者 | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | 登録日 | 2017-11-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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3V7Q
 | | Crystal structure of B. subtilis YlxQ at 1.55 A resolution | | 分子名称: | CITRIC ACID, POTASSIUM ION, Probable ribosomal protein ylxQ | | 著者 | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | | 登録日 | 2011-12-21 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops.
Rna, 18, 2012
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3VAD
 | | Crystal structure of I170F mutant branched-chain alpha-ketoacid dehydrogenase kinase in complex with 3,6-dichlorobenzo[b]thiophene-2-carboxylic acid | | 分子名称: | 3,6-dichloro-1-benzothiophene-2-carboxylic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ahmed, K, Gui, W.J, Tso, S.C, Chuang, J.L, Wynn, R.M, Chuang, D.T. | | 登録日 | 2011-12-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Crystal structure of I170F mutant branched-chain alpha-ketoacid dehydrogenase kinase in complex with 3,6-dichlorobenzo[b]thiophene-2-carboxylic acid
To be Published
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2JTK
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3K6U
 | | M. acetivorans Molybdate-Binding Protein (ModA) in Unliganded Open Form | | 分子名称: | Solute-binding protein MA_0280 | | 著者 | Chan, S, Giuroiu, I, Chernishof, I, Sawaya, M.R, Chiang, J, Gunsalus, R.P, Arbing, M.A, Perry, L.J. | | 登録日 | 2009-10-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans
Acta Crystallogr.,Sect.F, 66, 2010
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3V6P
 | | Crystal structure of the DNA-binding domain of dHax3, a TAL effector | | 分子名称: | dHax3 | | 著者 | Deng, D, Yan, C.Y, Pan, X.J, Wang, J.W, Shi, Y.G, Yan, N. | | 登録日 | 2011-12-20 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors
Science, 2012
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7E2B
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7XIO
 | | Crystal structure of TYR from Ralstonia | | 分子名称: | PHOSPHATE ION, Polyphenol oxidase | | 著者 | Sun, D.Y, Cui, P.P, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Zhang, J, Li, X, Zeng, Z.X. | | 登録日 | 2022-04-13 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of TYR from Ralstonia
To Be Published
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4FJY
 | | Crystal structure of PI3K-gamma in complex with quinoline-indoline inhibitor 24f | | 分子名称: | 4-[3,3-dimethyl-6-(morpholin-4-yl)-2,3-dihydro-1H-indol-1-yl]-7-fluoro-3-methyl-2-(pyridin-3-yl)quinoline, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | | 登録日 | 2012-06-12 | | 公開日 | 2012-10-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors
J.Med.Chem., 55, 2012
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2A3R
 | | Crystal Structure of Human Sulfotransferase SULT1A3 in Complex with Dopamine and 3-Phosphoadenosine 5-Phosphate | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, L-DOPAMINE, Monoamine-sulfating phenol sulfotransferase | | 著者 | Lu, J.H, Li, H.T, Liu, M.C, Zhang, J.P, Li, M, An, X.M, Chang, W.R. | | 登録日 | 2005-06-26 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate
Biochem.Biophys.Res.Commun., 335, 2005
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4KMP
 | | Structure of XIAP-BIR3 and inhibitor | | 分子名称: | (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], E3 ubiquitin-protein ligase XIAP, ZINC ION | | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | | 登録日 | 2013-05-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of XIAP-BIR3 and inhibitor
To be Published
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6BLH
 | | RSV G central conserved region bound to Fab CB017.5 | | 分子名称: | 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ... | | 著者 | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | 登録日 | 2017-11-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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1NPE
 | | Crystal structure of Nidogen/Laminin Complex | | 分子名称: | CADMIUM ION, Laminin gamma-1 chain, nidogen | | 著者 | Takagi, J, Yang, Y.T, Liu, J.-H, Wang, J.-H, Springer, T.A. | | 登録日 | 2003-01-17 | | 公開日 | 2003-08-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Complex between nidogen and laminin fragments reveals a paradigmatic
beta-propeller interface
Nature, 424, 2003
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7YFI
 | | Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and glutamate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | 著者 | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | | 登録日 | 2022-07-08 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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3SCX
 | | RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the Presence of Ca2+ | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ... | | 著者 | Wang, M, Wang, J, Konigsberg, W.H. | | 登録日 | 2011-06-08 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
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3SIQ
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