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PDB: 4145 件

7YUL
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Crystal structure of human BEND6 BEN domain in complex with DNA
分子名称: BEN domain-containing protein 6, DNA (5'-D(*CP*TP*CP*TP*CP*GP*CP*GP*AP*GP*AP*G)-3'), GLYCOLIC ACID
著者Liu, K, Xiao, Y.Q, Zhang, J, Min, J.R.
登録日2022-08-17
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
J.Biol.Chem., 299, 2023
6CI2
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Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, formyltransferase PseJ
著者Reimer, J.M, Jiang, J, Harb, I, Schmeing, T.M.
登録日2018-02-23
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain.
ACS Chem. Biol., 13, 2018
6R1B
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Crystal structure of UgpB from Mycobacterium tuberculosis in complex with glycerophosphocholine
分子名称: 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, GLYCEROL, MAGNESIUM ION, ...
著者Fenn, J, Nepravishta, R, Guy, C.S, Harrison, J, Angulo, J, Cameron, A.D, Fullam, E.
登録日2019-03-14
公開日2019-09-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.27000213 Å)
主引用文献Structural Basis of Glycerophosphodiester Recognition by theMycobacterium tuberculosisSubstrate-Binding Protein UgpB.
Acs Chem.Biol., 14, 2019
3OBY
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BU of 3oby by Molmil
Crystal structure of Archaeoglobus fulgidus Pelota reveals inter-domain structural plasticity
分子名称: Protein pelota homolog
著者Lee, H.H, Jang, J.Y, Yoon, H.-J, Kim, S.J, Suh, S.W.
登録日2010-08-09
公開日2010-09-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of two archaeal Pelotas reveal inter-domain structural plasticity
Biochem.Biophys.Res.Commun., 399, 2010
6GRP
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BU of 6grp by Molmil
Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P)
分子名称: 3,5,6-trichloro-2-pyridinol, SODIUM ION, Transthyretin
著者Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E.
登録日2018-06-12
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52, 2018
6GNO
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Crystal Structure Of Sea Bream Transthyretin in complex with Tetrabromobisphenol A (TBBPA)
分子名称: 4,4'-propane-2,2-diylbis(2,6-dibromophenol), SULFATE ION, Transthyretin
著者Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E.
登録日2018-05-31
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52, 2018
5FKP
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BU of 5fkp by Molmil
Crystal structure of the mouse CD1d in complex with the p99 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN-PRESENTING GLYCOPROTEIN CD1D1, BETA 2 MICROGLOBULIN, ...
著者Girardi, E, Wang, J, Zajonc, D.M.
登録日2015-10-18
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of an Alpha-Helical Peptide and Lipopeptide Bound to the Non-Classical Mhc Class I Molecule Cd1D
J.Biol.Chem., 291, 2016
5KIP
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BU of 5kip by Molmil
Asymmetric unit for the coat proteins of phage Qbeta
分子名称: Coat protein
著者Gorzelnik, K.V, Cui, Z, Zhang, J.
登録日2016-06-16
公開日2016-10-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Asymmetric cryo-EM structure of the canonical Allolevivirus Q beta reveals a single maturation protein and the genomic ssRNA in situ.
Proc.Natl.Acad.Sci.USA, 113, 2016
6FV6
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BU of 6fv6 by Molmil
Monomer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
分子名称: Aq128
著者Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
登録日2018-03-01
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Monomer structure of Aq128 in the outward-facing state
To Be Published
6FV8
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BU of 6fv8 by Molmil
Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
分子名称: Aq128
著者Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
登録日2018-03-01
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Dimer structure of the MATE family multidrug resistance transporter Aq128 in the outward-facing state
To Be Published
8SOZ
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BU of 8soz by Molmil
Structure of the complex formed by human interleukin-2 and scFv 602
分子名称: 602 single chain fragment variable, Interleukin-2
著者Gould, J.R, Leonard, E.K, Cao, S.D, Spangler, J.B.
登録日2023-04-30
公開日2024-09-04
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Engineered cytokine/antibody fusion proteins improve IL-2 delivery to pro-inflammatory cells and promote antitumor activity.
JCI Insight, 9, 2024
8SOW
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BU of 8sow by Molmil
Structure of the complex formed by human interleukin-2 and scFv F10
分子名称: F10 single chain fragment variable, Interleukin-2
著者Gould, J.R, Leonard, E.K, Cao, S.D, Spangler, J.B.
登録日2023-04-30
公開日2024-09-04
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Engineered cytokine/antibody fusion proteins improve IL-2 delivery to pro-inflammatory cells and promote antitumor activity.
JCI Insight, 9, 2024
4O6X
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BU of 4o6x by Molmil
Crystal structure of human Ankyrin G death domain
分子名称: Ankyrin-3
著者Liu, Y, Zhang, Y, Wang, J.H.
登録日2013-12-24
公開日2014-10-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Crystal structure of human Ankyrin G death domain.
Proteins, 82, 2014
8IG4
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BU of 8ig4 by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with GC376
分子名称: Non-structural protein 11, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zhou, X.L, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
5HRI
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BU of 5hri by Molmil
The crystal structure of AsfvPolX:DNA1 binary complex
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*CP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3', DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ...
著者Chen, Y.Q, Zhang, J, Gan, J.H.
登録日2016-01-23
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of AsfvPolX: 1nt-gap(P) DNA1: dGTP ternary complex.
To Be Published
8IG6
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Crystal structure of MERS main protease in complex with GC376
分子名称: N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, ORF1a
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG7
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BU of 8ig7 by Molmil
Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, P, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG5
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BU of 8ig5 by Molmil
Crystal structure of SARS main protease in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
3MP6
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BU of 3mp6 by Molmil
Complex Structure of Sgf29 and dimethylated H3K4
分子名称: H3K4me2 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Li, J, Wu, M, Ruan, J, Zang, J.
登録日2010-04-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
5HP4
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BU of 5hp4 by Molmil
Crystal structure bacteriohage T5 D15 flap endonuclease (D155K) pseudo-enzyme-product complex with DNA and metal ions
分子名称: CALCIUM ION, DNA (5'-D(*GP*AP*TP*CP*TP*AP*TP*AP*TP*GP*CP*CP*AP*TP*CP*GP*G)-3'), Exodeoxyribonuclease, ...
著者Almalki, F.A, Zhang, J, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.A.
登録日2016-01-20
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
8IG9
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BU of 8ig9 by Molmil
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zou, X.F, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG8
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BU of 8ig8 by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IGB
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BU of 8igb by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Li, W.W, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8INZ
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BU of 8inz by Molmil
Cryo-EM structure of human HCN3 channel in apo state
分子名称: 4-[[(2~{S},4~{a}~{R},6~{S},8~{a}~{S})-6-[(4~{S},5~{R})-4-[(2~{S})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
著者Yu, B, Lu, Q.Y, Li, J, Zhang, J.
登録日2023-03-10
公開日2024-04-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Cryo-EM structure of human HCN3 channel and its regulation by cAMP.
J.Biol.Chem., 300, 2024
7YFG
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BU of 7yfg by Molmil
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日2022-07-08
公開日2023-03-29
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-10-09に公開中

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